Publications,References

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease ...
Published: February, 2016

Abstract: In Graves' disease (GD), a combination of genetic, epigenetic and environmental factors causes an autoimmune response to the thyroid gland, charact... Read more »

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IP-Star

Protocol for Methylated DNA Immunoprecipitation (MeDIP) Analysis
Published: February, 2016

Abstract: DNA methylation is a fundamental epigenetic mechanism for silencing gene expression by either modifying chromatin structure to a repressive state o... Read more »

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Antibody 5mC (C15200081)

TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CT...
Published: February, 2016

Abstract: Intragenic 5-methylcytosine and CTCF mediate opposing effects on pre-mRNA splicing: CTCF promotes inclusion of weak upstream exons through RNA poly... Read more »

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Antibody

The Nuclear Ribonucleoprotein SmD1 Interplays with Splicing, RNA Qu...
Published: February, 2016

Abstract: RNA quality control (RQC) eliminates aberrant RNAs based on their atypical structure, whereas posttranscriptional gene silencing (PTGS) eliminates ... Read more »

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IP-Star Compact

The dual specificity phosphatase 2 gene is hypermethylated in human...
Published: February, 2016

Abstract: Dual specificity phosphatases are a class of tumor-associated proteins involved in the negative regulation of the MAP kinase pathway. Downregulatio... Read more »

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Antibody

Diagenode® Premium RRBS technology: cost-effective DNA methylation ...
Published: January, 2016

Abstract: Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis in any vertebrate species. The assay benefits from... Read more »

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Premium RRBS Kit

DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylati...
Published: January, 2016

Abstract: While phosphorus in the form of inorganic or organic phosphate is critically involved in most cellular functions, high plasma levels of inorganic p... Read more »

DNMT3L enables accumulation and inheritance of epimutations in tran...
Published: January, 2016

Abstract: DNMT3L is an important epigenetic regulator in mammals, integrating DNA methylation and histone modification based epigenetic circuits. Here we sho... Read more »

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IP-Star

Rapid immunoprecipitation mass spectrometry of endogenous proteins ...
Published: January, 2016

Abstract: Rapid immunoprecipitation mass spectrometry of endogenous protein (RIME) is a method that allows the study of protein complexes, in particular chro... Read more »

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Bioruptor Bioruptor Plus

RNA biochemistry. Transcriptome-wide distribution and function of R...
Published: January, 2016

Abstract: Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs... Read more »

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Antibody

Transcriptome-wide distribution and function of RNA hydroxymethylcy...
Published: January, 2016

Abstract: Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs... Read more »

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Antibody

Chromatin Immunoprecipitation Assay for the Identification of Arabi...
Published: January, 2016

Abstract: Intricate gene regulatory networks orchestrate biological processes and developmental transitions in plants. Selective transcriptional activation a... Read more »

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Bioruptor Antibody

De novo DNA methylation drives 5hmC accumulation in mouse zygotes
Published: January, 2016

Abstract: Zygotic epigenetic reprogramming entails genome-wide DNA demethylation that is accompanied by Tet methylcytosine dioxygenase 3 (Tet3)-driven oxidat... Read more »

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Antibody 5mC (C15200081)

Analysis of EZH2: micro-RNA network in low and high grade astrocyti...
Published: January, 2016

Abstract: Enhancer of Zeste homologue2 (EZH2) is an epigenetic regulator that functions as oncogene in astrocytic tumors, however, EZH2 regulation remains li... Read more »

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Bioruptor LowCell ChIP kit True MicroChIP kit Article alert

The chloroplastic DEVH-box RNA helicase INCREASED SIZE EXCLUSION LI...
Published: January, 2016

Abstract: INCREASED SIZE EXCLUSION LIMIT 2 (ISE2) encodes a putative DEVH-box RNA helicase originally identified through a genetic screening for Arabidopsis ... Read more »

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IP-Star Compact

The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcript...
Published: January, 2016

Abstract: The interplay between methylation and demethylation of histone lysine residues is an essential component of gene expression regulation and there is... Read more »

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Antibody

Regulation of miR-200c/141 expression by intergenic DNA-looping and...
Published: January, 2016

Abstract: The miR-200 family members have been implicated in stress responses and ovarian tumorigenesis. Here, we find that miR-200c/141 transcription is int... Read more »

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MagMeDIP kit

DOT1L Activity Promotes Proliferation and Protects Cortical Neural ...
Published: January, 2016

Abstract: Growing evidence suggests that the lysine methyltransferase DOT1L/KMT4 has important roles in proliferation, survival, and differentiation of stem ... Read more »

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Antibody

Identification and validation of WISP1 as an epigenetic regulator o...
Published: January, 2016

Abstract: Lymph node (LN) metastasis is the most important prognostic factor in oral squamous cell carcinoma (OSCC) patients. However, in approximately one t... Read more »

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MethylCap

Molecular basis and functional significance of Angiotensin II-induc...
Published: January, 2016

Abstract: Delineation of mechanisms underlying the regulation of fibrosis-related genes in the heart is an important clinical goal as cardiac fibrosis is a m... Read more »

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LowCell ChIP kit

Functional characterization of the hGRαT556I causing Chrousos syndrome
Published: January, 2016

Abstract: BACKGROUND: Chrousos syndrome is a rare pathologic condition characterized by generalized, partial resistance of target tissues to glucocorticoids... Read more »

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Antibody

DNA methylation in an engineered heart tissue model of cardiac hype...
Published: January, 2016

Abstract: DNA methylation affects transcriptional regulation and constitutes a drug target in cancer biology. In cardiac hypertrophy, DNA methylation may con... Read more »

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MethylCap

MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation...
Published: January, 2016

Abstract: Protein kinase C δ (PKCδ) and p38δ are key proteins in a cascade that stimulates keratinocyte differentiation. This cascade activ... Read more »

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LowCell ChIP kit

Transducin-like enhancer of split-1 is expressed and functional in ...
Published: December, 2015

Abstract: Macrophages display heterogeneous phenotypes, including the classical M1 proinflammatory and the alternative M2 anti-inflammatory polarization stat... Read more »

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Bioruptor Chromatin Shearing Article alert

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through...
Published: December, 2015

Abstract: Targeted therapies designed to exploit specific molecular pathways in aggressive cancers are an exciting area of current research. Mixed Lineage Le... Read more »

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Antibody

Epigenome-wide effects of vitamin D and their impact on the transcr...
Published: December, 2015

Abstract: The physiological functions of vitamin D are mediated by its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) activating the transcription ... Read more »

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Bioruptor Article alert

Standardizing chromatin research: a simple and universal method for...
Published: December, 2015

Abstract: Here we demonstrate that harmonization of ChIP-seq workflows across cell types and conditions is possible when obtaining chromatin from proper... Read more »

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Bioruptor H3K4me3 (C15410003) IP-Star Compact H3K27me3 (C15410195) Article alert

cChIP-seq: a robust small-scale method for investigation of histone...
Published: December, 2015

Abstract: Background ChIP-seq is highly utilized for mapping histone modifications that are informative about gene regulation and genome annotations. For ... Read more »

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Antibody

Embryonic transcription is controlled by maternally defined chromat...
Published: December, 2015

Abstract: Histone-modifying enzymes are required for cell identity and lineage commitment, however little is known about the regulatory origins of the epigen... Read more »

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Antibody

Reversion to an embryonic alternative splicing program enhances leu...
Published: December, 2015

Abstract: Formative research suggests that a human embryonic stem cell-specific alternative splicing gene regulatory network, which is repressed by Musclebli... Read more »

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Antibody

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