Publications,References

Rapid and highly efficient mammalian cell engineering via Cas9 prot...
Published: August, 2015

Abstract: CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. ... Read more »

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Antibody CRISPR Cas9 (C15200203)

LXR-Mediated ABCA1 Expression and Function Are Modulated by High Gl...
Published: August, 2015

Abstract: High cholesterol and diabetes are major risk factors for atherosclerosis. Regression of atherosclerosis is mediated in part by the Liver X Receptor... Read more »

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Article alert

Comparative analysis of anti-viral transcriptomics reveals novel ef...
Published: August, 2015

Abstract: BACKGROUND: Comparative analysis of genome-wide expression profiles are increasingly being used to study virus-specific host interactions. In or... Read more »

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IP-Star Compact

Runx1 Transcription Factor Is Required for Myoblasts Proliferation ...
Published: August, 2015

Abstract: Following myonecrosis, muscle satellite cells proliferate, differentiate and fuse, creating new myofibers. The Runx1 transcription factor is not ex... Read more »

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Article alert

Polycomb RING1A- and RING1B-dependent histone H2A monoubiquitylatio...
Published: August, 2015

Abstract: The functions of polycomb products extend beyond their well-known activity as transcriptional regulators to include genome duplication processes. P... Read more »

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Antibody

C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers duri...
Published: August, 2015

Abstract: Highlights C/EBPα activates two classes of prospective myeloid enhancers in B cells Pre-existing enhancers are bound by PU.1 and be... Read more »

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Antibody

Prenatal Exposure to DEHP Affects Spermatogenesis and Sperm DNA Met...
Published: August, 2015

Abstract: Di-(2-ethylhexyl)phtalate (DEHP) is a plasticizer with endocrine disrupting properties found ubiquitously in the environment and altering reproduct... Read more »

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MethylCap

Genome-wide hydroxymethylcytosine pattern changes in response to ox...
Published: August, 2015

Abstract: The TET enzymes convert methylcytosine to the newly discovered base hydroxymethylcytosine. While recent reports suggest that TETs may play a role... Read more »

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Antibody

Acetylations of Ftz-F1 and histone H4K5 are required for the fine-t...
Published: August, 2015

Abstract: The molting during Drosophila development is tightly regulated by the ecdysone hormone. Several steps of the ecdysone biosynthesis have been alread... Read more »

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Bioruptor Chromatin Shearing

Acetylation of intragenic histones on HPV16 correlates with enhance...
Published: August, 2015

Abstract: We report that many histone modifications are unevenly distributed over the HPV16 genome in cervical cancer cells as well as in HPV16-immortalized ... Read more »

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DNA shearing Bioruptor Chromatin Shearing

Folic acid administration inhibits amyloid β-peptide accumulation i...
Published: August, 2015

Abstract: Alzheimer's disease (AD) is associated with malnutrition, altered one-carbon metabolism and increased hippocampal amyloid-β peptide (Aβ) ... Read more »

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Bioruptor Cell Lysis

Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates tran...
Published: August, 2015

Abstract: Smooth muscle-22α (SM22α), encoded by transgelin (TAGLN), is expressed in mesenchymal lineage cells, including myofibroblasts and smoot... Read more »

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Bioruptor Chromatin Shearing

The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human...
Published: August, 2015

Abstract: UNLABELLED: The human interferon-inducible IFI16 protein, an innate immune sensor of intracellular DNA, was recently demonstrated to act as a restr... Read more »

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Bioruptor Chromatin Shearing

Condensin targets and reduces unwound DNA structures associated wit...
Published: July, 2015

Abstract: Chromosome condensation is a hallmark of mitosis in eukaryotes and is a prerequisite for faithful segregation of genetic material to daughter cells... Read more »

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Antibody

Non-coding recurrent mutations in chronic lymphocytic leukaemia.
Published: July, 2015

Abstract: Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations determining the clinicobiological behaviour are not full... Read more »

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Antibody

Deciphering the principles that govern mutually exclusive expressio...
Published: July, 2015

Abstract: The product of the Plasmodium falciparum genes clag3.1 and clag3.2 plays a fundamental role in malaria parasite biology by determining solute trans... Read more »

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Antibody

Evaluation of Methyl-Binding Domain Based Enrichment Approaches Rev...
Published: July, 2015

Abstract: Methyl-binding domain (MBD) enrichment followed by deep sequencing (MBD-seq), is a robust and cost efficient approach for methylome-wide associatio... Read more »

Arterial endothelial methylome: differential DNA methylation in ath...
Published: July, 2015

Abstract: BACKGROUND: Atherosclerosis is a heterogeneously distributed disease of arteries in which the endothelium plays an important central role. Spati... Read more »

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MagMeDIP kit

The complex pattern of epigenomic variation between natural yeast s...
Published: July, 2015

Abstract: BACKGROUND: Epigenomic studies on humans and model species have revealed substantial inter-individual variation in histone modification profiles... Read more »

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Antibody

The oncofusion protein FUS-ERG targets key hematopoietic regulators...
Published: July, 2015

Abstract: The ETS transcription factor ERG has been implicated as a major regulator of both normal and aberrant hematopoiesis. In acute myeloid leukemias har... Read more »

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Antibody

Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in ...
Published: July, 2015

Abstract: Endothelial to mesenchymal transition (EndMT) was originally described in heart development where the endocardial endothelial cells that line the a... Read more »

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tum...
Published: July, 2015

Abstract: Sox9 is a transcription factor expressed in most solid tumors. However, the molecular mechanisms underlying Sox9 function during tumorigenesis rema... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

DNA methylation directs functional maturation of pancreatic β cells
Published: July, 2015

Abstract: Pancreatic β cells secrete insulin in response to postprandial increases in glucose levels to prevent hyperglycemia and inhibit insulin secret... Read more »

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Antibody

Regulation of the expression of claudin 23 by the enhancer of zeste...
Published: July, 2015

Abstract: Altered epigenetic mechanisms, similar to gene mutations, contribute to the pathogenesis and molecular heterogeneity of neoplasms, including colore... Read more »

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Bioruptor Chromatin Shearing Bioruptor Plus

Transcription factor p63 bookmarks and regulates dynamic enhancers ...
Published: July, 2015

Abstract: The transcription factor p63 plays a pivotal role in keratinocyte proliferation and differentiation in the epidermis. However, how p63 regulates ep... Read more »

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Antibody

GCDCA down-regulates gene expression by increasing Sp1 binding to t...
Published: July, 2015

Abstract: During the course of cholestatic liver diseases, the toxic effect of bile acids accumulation has been related to the decreased expression of endoth... Read more »

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Bioruptor Cell Lysis

An Insulator Element Located at the Cyclin B1 Interacting Protein 1...
Published: June, 2015

Abstract: Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by ... Read more »

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LowCell ChIP kit

Histone H3.3 is required for endogenous retroviral element silencin...
Published: June, 2015

Abstract: Transposable elements comprise roughly 40% of mammalian genomes. They have an active role in genetic variation, adaptation and evolution through th... Read more »

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Bioruptor Chromatin Shearing

Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively rep...
Published: June, 2015

Abstract: The chromatin-modifying enzyme lysine-specific demethylase 1, KDM1A/LSD1 is involved in maintaining the undifferentiated, malignant phenotype of ne... Read more »

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Bioruptor Chromatin Shearing

Cistrome of the aldosterone-activated mineralocorticoid receptor in...
Published: June, 2015

Abstract: Aldosterone exerts its effects mainly by activating the mineralocorticoid receptor (MR), a transcription factor that regulates gene expression thro... Read more »

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HighCell ChIP kit

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