Publications,References

Epigenetic role of CCAAT box-binding transcription factor NF-Y on I...
Published: October, 2015

Abstract: Nuclear factor Y (NF-Y) is a histone substitute protein that specifically binds to the CCAAT box of the target genes and thereby promotes their reg... Read more »

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Article alert

A gene expression signature identifying transient DNMT1 depletion a...
Published: October, 2015

Abstract: Many human tumors show aberrant activation of a group of germline-specific genes, termed cancer-germline (CG) genes, several of which appear to exe... Read more »

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Antibody Article alert

Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Do...
Published: October, 2015

Abstract: α-synuclein, a protein enriched in Lewy bodies and highly implicated in neurotoxicity in Parkinson's disease, is distributed both at nerve te... Read more »

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Antibody

Optimized method for methylated DNA immuno-precipitation
Published: October, 2015

Abstract: Methylated DNA immunoprecipitation (MeDIP) is one of the most widely used methods to evaluate DNA methylation on a whole genome scale, and involves... Read more »

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Antibody

Loss of EZH2 results in precocious mammary gland development and ac...
Published: October, 2015

Abstract: Establishment and differentiation of mammary alveoli during pregnancy are controlled by prolactin through the transcription factors STAT5A and STAT... Read more »

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Antibody

A geminivirus-based guide RNA delivery system for CRISPR/Cas9 media...
Published: October, 2015

Abstract: CRISPR/Cas has emerged as potent genome editing technology and has successfully been applied in many organisms, including several plant species. Ho... Read more »

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Antibody CRISPR Cas9 (C15200203)

The genetic association of RUNX3 with ankylosing spondylitis can be...
Published: October, 2015

Abstract: The authors sought to identify the functional basis for the genetic association of single nucleotide polymorphisms (SNP), upstream of the RUNX3 pro... Read more »

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Antibody Article alert

VEGF-mediated cell survival in non-small-cell lung cancer: implicat...
Published: October, 2015

Abstract: AIMS: To evaluate the potential therapeutic utility of histone deacetylase inhibitors (HDACi) in targeting VEGF receptors in non-small-cell lung... Read more »

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Antibody

Loss of BAP1 function leads to EZH2-dependent transformation
Published: October, 2015

Abstract: The tumor suppressors BAP1 and ASXL1 interact to form a polycomb deubiquitinase complex that removes monoubiquitin from histone H2A lysine 119 (H2A... Read more »

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IP-Star Compact

ClpX stimulates the mitochondrial unfolded protein response (UPRmt)...
Published: October, 2015

Abstract: Proteostasis is crucial for life and maintained by cellular chaperones and proteases. One major mitochondrial protease is the ClpXP complex, which ... Read more »

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Antibody

Arabidopsis CMT3 activity is positively regulated by AtSIZ1-mediate...
Published: October, 2015

Abstract: The activities of mammalian DNA and histone methyltransferases are regulated by post-translational modifications such as phosphorylation and sumoyl... Read more »

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Antibody

∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in L...
Published: October, 2015

Abstract: Aberrant DNA methylation is a hallmark of cancer but mechanisms contributing to the abnormality remain elusive. We have previously shown that ∆DNMT... Read more »

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MethylCap

Disruption of KMT2D perturbs germinal center B cell development and...
Published: October, 2015

Abstract: Mutations in the gene encoding the KMT2D (or MLL2) methyltransferase are highly recurrent and occur early during tumorigenesis in diffuse large B c... Read more »

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Antibody

Polycomb repressive complex PRC1 spatially constrains the mouse emb...
Published: October, 2015

Abstract: The Polycomb repressive complexes PRC1 and PRC2 maintain embryonic stem cell (ESC) pluripotency by silencing lineage-specifying developmental regul... Read more »

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Antibody

The mycotoxin aflatoxin B1 stimulates Epstein–Barr virus-induced B-...
Published: September, 2015

Abstract: Although Epstein–Barr virus (EBV) infection is widely distributed, certain EBV-driven malignancies are geographically restricted. EBV-associa... Read more »

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Article alert

Assessment of global and gene-specific DNA methylation in rat liver...
Published: September, 2015

Abstract: Altered expression of tumor suppressor genes and oncogenes, which is regulated in part at the level of DNA methylation, is an important event invol... Read more »

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Article alert

Endothelial Msx1 transduces hemodynamic changes into an arteriogeni...
Published: September, 2015

Abstract: Collateral remodeling is critical for blood flow restoration in peripheral arterial disease and is triggered by increasing fluid shear stress in pr... Read more »

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Antibody

Regulatory role of PAK1 and CtBP1 in muscle chromatin
Published: September, 2015

Abstract: Researchers in this article showed that the co-repressor CtBP1 is present on the myogenin promoter with repressive histone marks. They found that p... Read more »

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Deep sequencing and de novo assembly of the mouse oocyte transcript...
Published: September, 2015

Abstract: BACKGROUND: Previously, a role was demonstrated for transcription in the acquisition of DNA methylation at imprinted control regions in oocytes.... Read more »

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Antibody

The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replicatio...
Published: September, 2015

Abstract: Human papillomaviruses (HPV) regulate their differentiation-dependent life cycles by activating a number of cellular pathways, such as the DNA dama... Read more »

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A high-resolution imaging approach to investigate chromatin archite...
Published: September, 2015

Abstract: We present ChromATin, a quantitative high-resolution imaging approach for investigating chromatin organization in complex tissues. This method ... Read more »

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Antibody

The MEF2-HDAC axis controls proliferation of mammary epithelial cel...
Published: September, 2015

Abstract: The MEF2-HDAC axis is a master regulator of different developmental programs and adaptive responses in adults. In this manuscript we have investiga... Read more »

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Article alert

Transcription Factor Repertoire of Homeostatic Eosinophilopoiesis
Published: September, 2015

Abstract: The production of mature eosinophils (Eos) is a tightly orchestrated process with the aim to sustain normal Eos levels in tissues while also mainta... Read more »

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IP-Star

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Ca...
Published: September, 2015

Abstract: RATIONALE: In chronic heart failure, increased adrenergic activation contributes to structural remodeling and altered gene expression. Although ad... Read more »

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Antibody

High cortisol in 5-year-old children causes loss of DNA methylation...
Published: September, 2015

Abstract: BACKGROUND: Childhood stress leads to increased risk of many adult diseases, such as major depression and cardiovascular disease. Studies show t... Read more »

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MagMeDIP kit

Immunohistochemical Detection of Oxidized Forms of 5-Methylcytosine...
Published: September, 2015

Abstract: DNA methylation (5-methylcytosine, 5mC) is a major epigenetic modification of the eukaryotic genome associated with gene repression. Ten-eleven tra... Read more »

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Antibody 5mC (C15200081)

Genome-wide p63-regulated gene expression in differentiating epider...
Published: September, 2015

Abstract: The transcription factor p63 is a key regulator in epidermal keratinocyte proliferation and differentiation. However, the role of p63 in gene regul... Read more »

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Antibody

Chromatin assembly factor CAF-1 represses priming of plant defence ...
Published: September, 2015

Abstract: Plants have evolved efficient defence systems against pathogens that often rely on specific transcriptional responses. Priming is part of the defen... Read more »

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Antibody

The Epigenome of Schistosoma mansoni Provides Insight about How Cer...
Published: August, 2015

Abstract: BACKGROUND: Chromatin structure can control gene expression and can define specific transcription states. For example, bivalent methylation of h... Read more »

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Antibody

Spatiotemporal control of estrogen-responsive transcription in ERα-...
Published: August, 2015

Abstract: Recruitment of transcription machinery to target promoters for aberrant gene expression has been well studied, but underlying control directed by d... Read more »

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Antibody

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