Publications,References

The histone variant composition of centromeres is controlled by the...
Published: August, 2014

Abstract: Correct chromosome segregation requires a unique chromatin environment at centromeres and in their vicinity. Here, we address how the deposition of... Read more »

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Antibody

Active CREB1 Promotes a Malignant TGFβ2 Autocrine Loop in Glioblast...
Published: August, 2014

Abstract: In advanced cancer, including glioblastoma, the TGFβ pathway acts as an oncogenic factor. Some tumors exhibit aberrantly high TGFβ activity, and th... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Human cytomegalovirus pUL79 is an elongation factor of RNA polymera...
Published: August, 2014

Abstract: In this study, we have identified a unique mechanism in which human cytomegalovirus (HCMV) protein pUL79 acts as an elongation factor to direct cel... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Regulation of broad by the Notch pathway affects timing of follicle...
Published: August, 2014

Abstract: During Drosophila oogenesis, activation of Notch signaling in the follicular epithelium (FE) around stage 6 of oogenesis is essential for entry int... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Source tracking of an anthrax outbreak in northeastern China using ...
Published: July, 2014

Abstract: Anthrax is caused by Bacillus anthracis, an etiological agent behind zoonotic diseases worldwide. B. anthracis is also one of the most dangerous bi... Read more »

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DNA shearing Bioruptor

Inhibition of euchromatic histone methyltransferase 1 and 2 sensiti...
Published: July, 2014

Abstract: BACKGROUND: H3K9 methylation is one of the essential histone post-translational modifications for heterochromatin formation and transcriptional rep... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

SOX2 is a cancer-specific regulator of tumour initiating potential ...
Published: July, 2014

Abstract: Although the principles that balance stem cell self-renewal and differentiation in normal tissue homeostasis are beginning to emerge, it is still u... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Lipid peroxidation product 4-hydroxy-2-nonenal modulates base excis...
Published: July, 2014

Abstract: Oxidative-stress-driven lipid peroxidation (LPO) is involved in the pathogenesis of several human diseases, including cancer. LPO products react wi... Read more »

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Bioruptor Cell Lysis Western Blot Enzymatic Assay

Identification of proteins associated with RNA polymerase III using...
Published: July, 2014

Abstract: To identify the proteins associated with the RNA polymerase III (Pol III) machinery in exponentially growing yeast cells, we developed our own tand... Read more »

Long noncoding RNA modulates alternative splicing regulators in Ara...
Published: July, 2014

Abstract: Alternative splicing (AS) of pre-mRNA represents a major mechanism underlying increased transcriptome and proteome complexity. Here, we show that t... Read more »

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IP-Star IP-Star Compact

Interlocked loops trigger lineage specification and stable fates in...
Published: July, 2014

Abstract: Multipotent precursors are plastic cells that generate different, stable fates at the correct number, place and time, to allow tissue and organ for... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chr...
Published: July, 2014

Abstract: Although great advances have been made in the treatment of pediatric acute lymphoblastic leukemia, up to one of five patients will relapse, and the... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone deacetylase 4 promotes ubiquitin-dependent proteasomal degr...
Published: July, 2014

Abstract: Phthalates, phthalic acid esters, are widely used as plasticizers to produce polymeric materials in industrial production of plastics and daily con... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

H19 and MEST gene expression and histone modification in blastocyst...
Published: July, 2014

Abstract: Vitrification of embryos is a routine procedure in many IVF laboratories. The effect of vitrification on gene expression and some modifications of ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit

Epigenetics and the Evolution of Darwin's Finches.
Published: July, 2014

Abstract: The prevailing theory for the molecular basis of evolution involves genetic mutations that ultimately generate the heritable phenotypic variation o... Read more »

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Antibody

AhR and Arnt differentially regulate NF-κB signaling and chemokine ...
Published: July, 2014

Abstract: BACKGROUND: The aryl hydrocarbon receptor (AhR) has gradually emerged as a regulator of inflammation in the lung and other tissues. AhR may interac... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR HighCell ChIP kit

Concerted activities of distinct H4K20 methyltransferases at DNA do...
Published: July, 2014

Abstract: Although selective binding of 53BP1 to dimethylated histone H4 lysine 20 (H4K20me2) at DNA double-strand breaks (DSBs) is a necessary and pivotal d... Read more »

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Bioruptor Chromatin Shearing

DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide.
Published: July, 2014

Abstract: Genomic DNA is under constant assault by endogenous and exogenous DNA damaging agents. DNA breakage can represent a major threat to genome integrit... Read more »

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DNA shearing Bioruptor

Homozygous missense variant in the human CNGA3 channel causes cone-...
Published: July, 2014

Abstract: We assessed a large consanguineous Pakistani family (PKAB157) segregating early onset low vision problems. Funduscopic and electroretinographic eva... Read more »

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DNA shearing Bioruptor

Genome-Wide Characterization of Light-Regulated Genes in Neurospora...
Published: July, 2014

Abstract: The filamentous fungus Neurospora crassa responds to light in complex ways. To thoroughly study the transcriptional response of this organism to li... Read more »

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DNA shearing Bioruptor

DAB2IP regulates cancer stem cell phenotypes through modulating ste...
Published: July, 2014

Abstract: Cancer stem cell (CSC), the primary source of cancer-initiating population, is involved in cancer recurrence and drug-resistant phenotypes. This st... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Activating germline mutations in STAT3 cause early-onset multi-orga...
Published: July, 2014

Abstract: Monogenic causes of autoimmunity provide key insights into the complex regulation of the immune system. We report a new monogenic cause of autoimmu... Read more »

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DNA shearing Bioruptor

Changes in histone methylation and acetylation during microspore re...
Published: July, 2014

Abstract: In response to stress treatments, microspores can be reprogrammed to become totipotent cells that follow an embryogenic pathway producing haploid a... Read more »

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Antibody

Loss of neuronal 3D chromatin organization causes transcriptional a...
Published: July, 2014

Abstract: The interior of the neuronal cell nucleus is a highly organized three-dimensional (3D) structure where regions of the genome that are linearly mill... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody

An AUG Codon Conserved for Protein Function Rather than Translation...
Published: July, 2014

Abstract: Elk1 belongs to the ternary complex (TCF) subfamily of the ETS-domain transcription factors. Several studies have implicated an important function ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Eaf5/7/3 form a functionally independent NuA4 submodule linked to R...
Published: July, 2014

Abstract: The NuA4 histone acetyltransferase complex is required for gene regulation, cell cycle progression, and DNA repair. Dissection of the 13-subunit co... Read more »

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Bioruptor Chromatin Shearing

Genomic organization and evolution of double minutes/homogeneously ...
Published: July, 2014

Abstract: The mechanism for generating double minutes chromosomes (dmin) and homogeneously staining regions (hsr) in cancer is still poorly understood. Throu... Read more »

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DNA shearing Bioruptor

Development of a lentivirus vector-based assay for non-destructive ...
Published: July, 2014

Abstract: Cell-to-cell fusion can be quantified by endowing acceptor and donor cells with latent reporter genes/proteins and activators of these genes/protei... Read more »

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Antibody

PHD and TFIIS-Like Domains of the Bye1 Transcription Factor Determi...
Published: July, 2014

Abstract: The BYpass of Ess1 (Bye1) protein is a putative S. cerevisiae transcription factor homologous to the human cancer-associated PHF3/DIDO family of pr... Read more »

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Antibody

The active enhancer network operated by liganded RXR supports angio...
Published: July, 2014

Abstract: RXR signaling is predicted to have a major impact in macrophages, but neither the biological consequence nor the genomic basis of its ligand activa... Read more »

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