Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Automating ChIP-seq Experiments to Generate Epigenetic Profiles on ...
Published: October, 2014

Abstract: Chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) is a technique of choice for studying protein-DNA interactions. ChI... Read more »

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IP-Star
MeDIP-on-Chip for Methylation Profiling
Published: October, 2014

Abstract: DNA methylation is an important regulatory step in gene expression. Knowledge of the alterations in DNA methylation at a whole genome scale improve... Read more »

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DNA shearing Bioruptor
Chromatin features of plant telomeric sequences at terminal versus ...
Published: October, 2014

Abstract: Epigenetic mechanisms are involved in regulation of crucial cellular processes in eukaryotic organisms. Data on the epigenetic features of plant te... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
White matter tract and glial-associated changes in 5-hydroxymethylc...
Published: October, 2014

Abstract: White matter abnormalities due to age-related cerebrovascular alterations is a common pathological hallmark associated with functional impairment i... Read more »

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Antibody
Inactivation of Phaeodactylum tricornutum urease gene using transcr...
Published: October, 2014

Abstract: Diatoms are unicellular photosynthetic algae with promise for green production of fuels and other chemicals. Recent genome-editing techniques have ... Read more »

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Bioruptor Cell Lysis Western Blot
Notch signaling regulates myogenic regenerative capacity of murine ...
Published: October, 2014

Abstract: Somatic stem cells hold attractive potential for the treatment of muscular dystrophies (MDs). Mesoangioblasts (MABs) constitute a myogenic subset o... Read more »

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DNA shearing Bioruptor
HDAC6-ubiquitin interaction controls the duration of HSF1 activatio...
Published: October, 2014

Abstract: After heat-shock, HSF1 controls a major cellular transcriptional response involving the activation of early (Hsp70) and late (Hsp25) heat shock gen... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
cAMP Responsive Element Binding Protein (CREB) and cAMP Co-regulate...
Published: October, 2014

Abstract: To regenerate damaged axons, neurons must express a cassette of regeneration-associated genes (RAGs) that increases intrinsic growth capacity and c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
Comparative Study of Seven Commercial Kits for Human DNA Extraction...
Published: October, 2014

Abstract: Human genomic DNA extracted from urine could be an interesting tool for large-scale public health studies involving characterization of genetic var... Read more »

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Master Mix
Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter...
Published: October, 2014

Abstract: Epigenetic mechanisms regulate programmed gene expression during prenatal neurogenesis and serve as a mediator between genetics and environment in ... Read more »
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial c...
Published: October, 2014

Abstract: The RAS/ERK pathway is commonly activated in carcinomas and promotes oncogenesis by altering transcriptional programs. However, the array of cis-re... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Cellular uptake behaviour, photothermal therapy performance, and cy...
Published: October, 2014

Abstract: With the development of Au nanorods for a number of biomedical applications, understanding their cellular responses has become increasingly importa... Read more »

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Bioruptor Cell Lysis
Validation of a sensitive DNA walking strategy to characterise unau...
Published: October, 2014

Abstract: To identify unauthorised GMOs in food and feed matrices, an integrated approach has recently been developed, targetting pCAMBIA family vectors, abu... Read more »

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Master Mix
The Polycomb Group Gene EMF2B is essential for maintenance of flora...
Published: October, 2014

Abstract: The Polycomb Repressive Complex 2 (PRC2) represses transcriptional activity of target genes through trimethylation of Lysine 27 of Histone H3. The ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Obesity increases histone H3 lysine 9 and 18 acetylation at Tnfa an...
Published: October, 2014

Abstract: Obesity contributes to the development of non‑alcoholic fatty liver disease (NAFLD), which is characterized by the upregulated expression of two ke... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003) Bioruptor Plus
Altered promoter nucleosome positioning is an early event in gene s...
Published: October, 2014

Abstract: Gene silencing in cancer frequently involves hypermethylation and dense nucleosome occupancy across promoter regions. How a promoter transitions to... Read more »

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DNA shearing Bioruptor
SOX11 promotes tumor angiogenesis through transcriptional regulatio...
Published: October, 2014

Abstract: SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs). We have recently proven that SO... Read more »

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Bioruptor Chromatin Shearing HighCell ChIP kit IPure kit
Integrator Regulates Transcriptional Initiation and Pause Release f...
Published: October, 2014

Abstract: In unicellular organisms, initiation is the rate-limiting step in transcription; in metazoan organisms, the transition from initiation to productiv... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Active and passive demethylation of male and female pronuclear DNA ...
Published: October, 2014

Abstract: The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embr... Read more »

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Antibody
Predicting interactome networks perturbations in human cancer: appl...
Published: October, 2014

Abstract: Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagn... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Hairy root transformation using Agrobacterium rhizogenes as a tool ...
Published: October, 2014

Abstract: Agrobacterium rhizogenes (or Rhizobium rhizogenes) is able to transform plant genomes and induce the production of hairy roots. We describe the use... Read more »

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Bioruptor Chromatin Shearing
Autophagy Controls BCG-Induced Trained Immunity and the Response to...
Published: October, 2014

Abstract: The anti-tuberculosis-vaccine Bacillus Calmette-Guérin (BCG) is the most widely used vaccine in the world. In addition to its effects against tuber... Read more »

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Antibody
The PML-associated protein DEK regulates the balance of H3.3 loadin...
Published: October, 2014

Abstract: Histone variant H3.3 is deposited in chromatin at active sites, telomeres, and pericentric heterochromatin by distinct chaperones, but the mechanis... Read more »

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Bioruptor Chromatin Shearing Antibody
Epigenetic mechanisms regulate placental c-myc and hTERT in normal ...
Published: October, 2014

Abstract: Placental development is known for its resemblance with tumor development, such as in the expression of oncogenes (c-myc) and telomerase (hTERT). T... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
A NOTCH1-driven MYC enhancer promotes T cell development, transform...
Published: October, 2014

Abstract: Efforts to identify and annotate cancer driver genetic lesions have been focused primarily on the analysis of protein-coding genes; however, most g... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Head formation: OTX2 regulates Dkk1 and Lhx1 activity in the anteri...
Published: October, 2014

Abstract: The Otx2 gene encodes a paired-type homeobox transcription factor that is essential for the induction and the patterning of the anterior structures... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide mapping of yeast histone chaperone anti-silencing funct...
Published: September, 2014

Abstract: Genome-wide participation and importance of the histone chaperone Asf1 (Anti-Silencing Function 1) in diverse DNA transactions like replication, re... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
c-Rel Regulates Ezh2 Expression in Activated Lymphocytes and Malign...
Published: September, 2014

Abstract: The Polycomb group protein Ezh2 is a histone methyltransferase that modifies chromatin structure to alter gene expression during embryonic developm... Read more »

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Bioruptor
Co-regulated expression of Na+/phosphate Pho89 transporter and Ena1...
Published: September, 2014

Abstract: The yeast Saccharomyces cerevisiae has two main high-affinity inorganic phosphate (Pi) transporters, Pho84 and Pho89, functionally relevant at acid... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq Bioruptor Plus

 


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