Publications,References

Retrotransposon-based profiling of mammalian epigenomes: DNA methyl...
Published: September, 2014

Abstract: In the current study, we have used HT-TREBS to individually analyze the DNA methylation pattern of 4799 IAP LTR retrotransposons in embryonic stem,... Read more »

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DNA shearing Bioruptor

An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 a...
Published: September, 2014

Abstract: Throughout evolution primate genomes have been modified by waves of retrotransposon insertions. For each wave, the host eventually finds a way to r... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

The specific alteration of histone methylation profiles by DZNep du...
Published: September, 2014

Abstract: Early embryo development constitutes a unique opportunity to study acquisition of epigenetic marks, including histone methylation. This study inves... Read more »

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Antibody

Co-detection and sequencing of genes and transcripts from the same ...
Published: September, 2014

Abstract: Despite the recent advance of single-cell gene expression analyses, co-measurement of both genomic and transcriptional signatures at the single-cel... Read more »

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DNA shearing Bioruptor

Significance of glioma-associated oncogene homolog 1 (GLI1) express...
Published: September, 2014

Abstract: IntroductionThe recently identified claudin-low subtype of breast cancer is enriched for cells with stem-like and mesenchymal-like characteristics.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Vitamin d receptor-mediated stromal reprogramming suppresses pancre...
Published: September, 2014

Abstract: The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) is attributed to intrinsic chemoresistance and a growth-permissive tumor microe... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

SET8 methyltransferase activity during the DNA double-strand break ...
Published: September, 2014

Abstract: DNA double-strand breaks (DSBs) activate a signaling pathway known as the DNA damage response (DDR) which via protein–protein interactions and post... Read more »

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Antibody

Transducin-like enhancer of split 3 (TLE3) in adipose tissue is inc...
Published: September, 2014

Abstract: Transgenic overexpression of adipose tissue (AT) transducin-like enhancer of split 3 (TLE3) mimicked peroxisome proliferator-activated receptor gam... Read more »

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Master Mix

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediate...
Published: September, 2014

Abstract: Depression is a debilitating condition with a profound impact on quality of life for millions of people worldwide. Physical exercise is used as a t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Tra...
Published: September, 2014

Abstract: In mammals, cytosine methylation (5mC) is widely distributed throughout the genome but is notably depleted from active promoters and enhancers. Whi... Read more »

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DNA shearing Bioruptor

Dysregulation of genome-wide gene expression and DNA methylation in...
Published: September, 2014

Abstract: BACKGROUND: Epigenetic modifications (especially altered DNA methylation) resulting in altered gene expression may be one reason for development fa... Read more »

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MagMeDIP kit

Evidence that breast cancer risk at the 2q35 locus is mediated thro...
Published: September, 2014

Abstract: GWAS have identified a breast cancer susceptibility locus on 2q35. Here we report the fine mapping of this locus using data from 101,943 subjects f... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

NF-κB Transcriptional Activity Is Modulated by FK506-binding Protei...
Published: September, 2014

Abstract: Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biological responses. With the purpose to... Read more »

Epigenetic events determine tissue-specific toxicity of inhalationa...
Published: September, 2014

Abstract: 1,3-Butadiene (BD), a widely used industrial chemical and a ubiquitous environmental pollutant, is a known human carcinogen. Although genotoxicity ... Read more »

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DNA shearing

Asparagine synthetase deficiency detected by whole exome sequencing...
Published: September, 2014

Abstract: Deficiency of Asparagine Synthetase (ASNSD, MIM 615574) is a very rare autosomal recessive disorder presenting with some brain abnormalities. Affec... Read more »

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DNA shearing Bioruptor

Measuring fast gene dynamics in single cells with timelapse lumines...
Published: September, 2014

Abstract: Timelapse fluorescence microscopy is an important tool for measuring in vivo gene dynamics in single cells. However, fluorescent proteins are limit... Read more »

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Bioruptor

Genome-wide map of regulatory interactions in the human genome.
Published: September, 2014

Abstract: Increasing evidence suggests that interactions between regulatory genomic elements play an important role in regulating gene expression. We generat... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

SNAIL1 combines competitive displacement of ASCL2 and epigenetic me...
Published: September, 2014

Abstract: EPHB3 is a critical cellular guidance factor in the intestinal epithelium and an important tumor suppressor in colorectal cancer (CRC) whose expres... Read more »

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Bioruptor Chromatin Shearing Antibody Bioruptor Plus

Genome-wide CNV analysis in 221 unrelated patients and targeted hig...
Published: September, 2014

Abstract: To uncover novel causative genes in patients with unexplained adenomatous polyposis, a model disease for colorectal cancer, we performed a genome-w... Read more »

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DNA shearing Bioruptor

Spontaneous sleep-wake cycle and sleep deprivation differently indu...
Published: September, 2014

Abstract: Brain-derived neurotrophic factor (Bdnf) regulates neuronal plasticity, slow wave activity and sleep homeostasis. Environmental stimuli control Bdn... Read more »

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Antibody 5mC (C15200081)

6-methoxyflavone inhibits NFAT translocation into the nucleus and s...
Published: September, 2014

Abstract: NFAT plays a crucial role in the immune system by regulating the transcription of inducible genes during immune responses. In T cells, NFAT protein... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induce...
Published: September, 2014

Abstract: AIMS: Ultraviolet irradiation and carcinogens have been reported to induce epigenetic alterations, which potentially contribute to the development ... Read more »

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MagMeDIP kit

TELP, a sensitive and versatile library construction method for nex...
Published: September, 2014

Abstract: Next-generation sequencing has been widely used for the genome-wide profiling of histone modifications, transcription factor binding and gene expre... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

Comparison of TALE designer transcription factors and the CRISPR/dC...
Published: September, 2014

Abstract: The transcription activator-like effectors (TALEs) and the RNA-guided clustered regularly interspaced short palindromic repeat (CRISPR) associated ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Shigella flexneri targets the HP1γ subcode through the phosphothreo...
Published: September, 2014

Abstract: HP1 proteins are transcriptional regulators that, like histones, are targets for post-translational modifications defining an HP1-mediated subcode.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The DEK oncoprotein binds to highly and ubiquitously expressed gene...
Published: September, 2014

Abstract: BACKGROUND: The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. Whil... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Up to date sample preparation of proteins for mass spectrometric an...
Published: September, 2014

Abstract: Abstract For the identification of proteins from biological samples by mass spectrometry there are two scenarios. Proteins are pre-fractionated in ... Read more »

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Bioruptor Tissue Homogenization

Target enrichment of ultraconserved elements from arthropods provid...
Published: September, 2014

Abstract: Gaining a genomic perspective on phylogeny requires the collection of data from many putatively independent loci across the genome. Among insects, ... Read more »

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DNA shearing Bioruptor

Neural stem cell differentiation is dictated by distinct actions of...
Published: September, 2014

Abstract: Signaling factors including retinoic acid (RA) and thyroid hormone (T3) promote neuronal, oligodendrocyte, and astrocyte differentiation of cortica... Read more »

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Bioruptor Chromatin Shearing ChIP-seq HighCell ChIP kit

Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphoc...
Published: September, 2014

Abstract: BackgroundIdentification of novel genetic risk factors is imperative for a better understanding of B lymphomagenesis and for the development of nov... Read more »

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Antibody

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