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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Fat specific protein 27 inhibits lipolysis by facilitating the inhi...
Published: May, 2014
Abstract: Lipolysis in fat tissue represents a major source of circulating fatty acids. Previously, we have found that lipolysis in adipocytes is controlled ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A genome-wide analysis of Cas9 binding specificity using ChIP-seq a...
Published: May, 2014
Abstract: Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome e... Read more »
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DNA shearing Bioruptor
Quiescence-Induced LncRNAs Trigger H4K20 Trimethylation and Transcr...
Published: May, 2014
Abstract: A complex network of regulatory pathways links transcription to cell growth and proliferation. Here we show that cellular quiescence alters chromat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Regulating Set-β's Subcellular Localization Toggles Its Function be...
Published: May, 2014
Abstract: The failure of the CNS neurons to regenerate axons after injury or stroke is a major clinical problem. Transcriptional regulators like Set-β are we... Read more »
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Bioruptor Cell Lysis Western Blot
Altered oral viral ecology in association with periodontal disease.
Published: May, 2014
Abstract: UNLABELLED: The human oral cavity is home to a large and diverse community of viruses that have yet to be characterized in patients with periodonta... Read more »
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DNA shearing Bioruptor
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogr...
Published: May, 2014
Abstract: Tumour cells sustain their high proliferation rate through metabolic reprogramming, whereby cellular metabolism shifts from oxidative phosphorylati... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K4me3 (C15410003)
Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) anal...
Published: May, 2014
Abstract: The ability of chromatin to switch back and forth from open euchromatin to closed heterochromatin is vital for transcriptional regulation and genom... Read more »
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Bioruptor Chromatin Shearing
Expanding the chemical diversity of natural esters by engineering a...
Published: May, 2014
Abstract: Microbial fatty acid (FA)-derived molecules have emerged as promising alternatives to petroleum-based chemicals for reducing dependence on fossil h... Read more »
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Bioruptor Cell Lysis Western Blot
Discovery of transgene insertion sites by high throughput sequencin...
Published: May, 2014
Abstract: BACKGROUND: Transgenesis by random integration of a transgene into the genome of a zygote has become a reliable and powerful method for the creatio... Read more »
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DNA shearing Bioruptor
Homeostatic maintenance of allele-specific p16 methylation in cance...
Published: May, 2014
Abstract: AIM: p16 Methylation frequently occurs in carcinogenesis. While it has been hypothesized that the p16 methylation states are dynamically maintained... Read more »
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DNA shearing Bioruptor
Parallel profiling of the transcriptome, cistrome, and epigenome in...
Published: May, 2014
Abstract: The DNA damage response (DDR) is a vast signaling network that is robustly activated by DNA double-strand breaks, the critical lesion induced by io... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Massive gene amplification drives paediatric hepatocellular carcino...
Published: May, 2014
Abstract: Hepatocellular carcinoma (HCC) is almost invariably associated with an underlying inflammatory state, whose direct contribution to the acquisition ... Read more »
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DNA shearing Bioruptor
Androgen-dependent Sertoli cell tight junction remodeling is mediat...
Published: May, 2014
Abstract: Sertoli cell tight junctions (SCTJs) of the seminiferous epithelium create a specialized microenvironment in the testis to aid differentiation of s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
IL-22 negatively regulates Helicobacter pylori-induced CCL20 expres...
Published: May, 2014
Abstract: Helicobacter pylori is a Gram-negative bacterium that infects the human gastric mucosa and causes various gastric diseases. H. pylori infection ind... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transmission from centenarians to their offspring of mtDNA heteropl...
Published: May, 2014
Abstract: The role that mtDNA heteroplasmy plays in healthy aging, familial longevity and the heritability patterns of low levels heteroplasmy in the elderly... Read more »
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DNA shearing Bioruptor
IL-15 regulates Bcl-2 family members Bim and Mcl-1 through JAK/STAT...
Published: May, 2014
Abstract: Maintenance of T cells is determined by their survival capacity, which is regulated by Bcl-2 proteins. Cytokines signalling through the common gamm... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Promyelocytic Leukaemia Zinc Finger Retinoic Acid Receptor α (PLZF-...
Published: May, 2014
Abstract: PLZF-RARα is an oncogene transcriptional repressor that is generated by a chromosomal translocation between the PLZF and RARα genes in acute promye... Read more »
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MeDIP kit
The LIM domain protein nTRIP6 recruits the mediator complex to AP-1...
Published: May, 2014
Abstract: Several LIM domain proteins regulate transcription. They are thought to act through their LIM protein-protein interaction domains as adaptors for t... Read more »
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Antibody
Genomic analysis of the emergence of 20th century epidemic dysentery.
Published: May, 2014
Abstract: BACKGROUND: Shigella dysenteriae type 1 (Sd1) causes recurrent epidemics of dysentery associated with high mortality in many regions of the world. ... Read more »
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DNA shearing Bioruptor
The Transcriptional Regulators TAZ and YAP Direct Transforming Grow...
Published: May, 2014
Abstract: Uncontrolled transforming growth factor-β (TGFβ) signaling promotes aggressive metastatic properties in late-stage breast cancers. However, how TGF... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Insights into how Spt5 functions in transcription elongation and re...
Published: May, 2014
Abstract: Spt5, a transcription elongation factor, and Rpb4, a subunit of RNA polymerase II (RNAP II) that forms a subcomplex with Rpb7, play important roles... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Sleep Fragmentation During Late Gestation Induces Metabolic Perturb...
Published: May, 2014
Abstract: Sleep fragmentation (SF) is a common condition among pregnant women, particularly during late gestation. Gestational perturbations promote the emer... Read more »
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Antibody
Identification of regulators of the three-dimensional polycomb orga...
Published: May, 2014
Abstract: Polycomb group (PcG) proteins dynamically define cellular identities through epigenetic repression of key developmental genes. PcG target gene repr... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Nitric oxide-induced neuronal to glial lineage fate-change depends ...
Published: May, 2014
Abstract: Degeneration of CNS tissue commonly occurs during neuroinflammatory conditions, such as multiple sclerosis (MS) and neurotrauma. During such condit... Read more »
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Antibody H3K27me3 (C15410069) H3K27ac (C15410174) H3pan (C15310135)
Dendritic cell development requires histone deacetylase activity.
Published: May, 2014
Abstract: DCs develop from multipotent progenitors (MPPs), which commit into DC-restricted common dendritic cell progenitors (CDPs). CDPs further differentia... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
The extent of error-prone replication-restart by homologous recombi...
Published: May, 2014
Abstract: Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains st... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Biogeography and phylogenomics of New World Bambusoideae (Poaceae),...
Published: May, 2014
Abstract: • Premise of the study: New World Bambusoideae have only recently been studied in a phylogenomic context. Plastome sequences were determined and an... Read more »
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DNA shearing Bioruptor
Myostatin Regulates Energy Homeostasis in the Heart and Prevents He...
Published: May, 2014
Abstract: RATIONALE: Myostatin is a major negative regulator of skeletal muscle mass and initiates multiple metabolic changes including enhanced insulin sens... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Fetal programming of adult Leydig cell function by androgenic effec...
Published: May, 2014
Abstract: Fetal growth plays a role in programming of adult cardiometabolic disorders, which in men, are associated with lowered testosterone levels. Fetal g... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enriched domain detector: a program for detection of wide genomic e...
Published: May, 2014
Abstract: Nuclear lamins contact the genome at the nuclear periphery through large domains and are involved in chromatin organization. Among broad peak calli... Read more »
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Bioruptor Chromatin Shearing ChIP-seq

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