Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The chloroplastic DEVH-box RNA helicase INCREASED SIZE EXCLUSION LI...
Published: January, 2016

Abstract: INCREASED SIZE EXCLUSION LIMIT 2 (ISE2) encodes a putative DEVH-box RNA helicase originally identified through a genetic screening for Arabidopsis ... Read more »

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IP-Star Compact
The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcript...
Published: January, 2016

Abstract: The interplay between methylation and demethylation of histone lysine residues is an essential component of gene expression regulation and there is... Read more »

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Antibody
Regulation of miR-200c/141 expression by intergenic DNA-looping and...
Published: January, 2016

Abstract: The miR-200 family members have been implicated in stress responses and ovarian tumorigenesis. Here, we find that miR-200c/141 transcription is int... Read more »

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MagMeDIP kit
DOT1L Activity Promotes Proliferation and Protects Cortical Neural ...
Published: January, 2016

Abstract: Growing evidence suggests that the lysine methyltransferase DOT1L/KMT4 has important roles in proliferation, survival, and differentiation of stem ... Read more »

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Antibody
Identification and validation of WISP1 as an epigenetic regulator o...
Published: January, 2016

Abstract: Lymph node (LN) metastasis is the most important prognostic factor in oral squamous cell carcinoma (OSCC) patients. However, in approximately one t... Read more »

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MethylCap
Molecular basis and functional significance of Angiotensin II-induc...
Published: January, 2016

Abstract: Delineation of mechanisms underlying the regulation of fibrosis-related genes in the heart is an important clinical goal as cardiac fibrosis is a m... Read more »

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LowCell ChIP kit
Functional characterization of the hGRαT556I causing Chrousos syndrome
Published: January, 2016

Abstract: BACKGROUND: Chrousos syndrome is a rare pathologic condition characterized by generalized, partial resistance of target tissues to glucocorticoids... Read more »

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Antibody
DNA methylation in an engineered heart tissue model of cardiac hype...
Published: January, 2016

Abstract: DNA methylation affects transcriptional regulation and constitutes a drug target in cancer biology. In cardiac hypertrophy, DNA methylation may con... Read more »

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MethylCap
MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation...
Published: January, 2016

Abstract: Protein kinase C δ (PKCδ) and p38δ are key proteins in a cascade that stimulates keratinocyte differentiation. This cascade activ... Read more »

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LowCell ChIP kit
Transducin-like enhancer of split-1 is expressed and functional in ...
Published: December, 2015

Abstract: Macrophages display heterogeneous phenotypes, including the classical M1 proinflammatory and the alternative M2 anti-inflammatory polarization stat... Read more »

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Bioruptor Chromatin Shearing Article alert
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through...
Published: December, 2015

Abstract: Targeted therapies designed to exploit specific molecular pathways in aggressive cancers are an exciting area of current research. Mixed Lineage Le... Read more »

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Antibody
Epigenome-wide effects of vitamin D and their impact on the transcr...
Published: December, 2015

Abstract: The physiological functions of vitamin D are mediated by its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) activating the transcription ... Read more »

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Bioruptor Article alert
Standardizing chromatin research: a simple and universal method for...
Published: December, 2015

Abstract: Here we demonstrate that harmonization of ChIP-seq workflows across cell types and conditions is possible when obtaining chromatin from proper... Read more »

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Bioruptor H3K4me3 (C15410003) IP-Star Compact H3K27me3 (C15410195) Article alert
cChIP-seq: a robust small-scale method for investigation of histone...
Published: December, 2015

Abstract: Background ChIP-seq is highly utilized for mapping histone modifications that are informative about gene regulation and genome annotations. For ... Read more »

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Antibody
Embryonic transcription is controlled by maternally defined chromat...
Published: December, 2015

Abstract: Histone-modifying enzymes are required for cell identity and lineage commitment, however little is known about the regulatory origins of the epigen... Read more »

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Antibody
Reversion to an embryonic alternative splicing program enhances leu...
Published: December, 2015

Abstract: Formative research suggests that a human embryonic stem cell-specific alternative splicing gene regulatory network, which is repressed by Musclebli... Read more »

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Antibody
Germline organization in Strongyloides nematodes reveals alternativ...
Published: December, 2015

Abstract: Nematodes of the genus Strongyloides are important parasites of vertebrates including man. Currently, little is known about their germline organiza... Read more »

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Antibody
Maternal immune activation induces GAD1 and GAD2 promoter remodelin...
Published: December, 2015

Abstract: Maternal infection during pregnancy increases the risk of neurodevelopmental disorders in the offspring. In addition to its influence on other neur... Read more »

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MagMeDIP kit
Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Ly...
Published: December, 2015

Abstract: The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted gene... Read more »

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Antibody
Valproic acid exposure leads to upregulation and increased promoter...
Published: December, 2015

Abstract: Valproic acid (VPA) is a widely used antiepileptic drug and first-line treatment in bipolar disorder, although the mechanisms underlying its therap... Read more »
DNA methylation profiling: comparison of genome-wide sequencing met...
Published: December, 2015

Abstract: AIMS: To compare the performance of four sequence-based and one microarray methods for DNA methylation profiling. METHODS: DNA from two cell l... Read more »

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MagMeDIP kit Antibody 5mC (C15200081)
Methionine-dependent histone methylation at developmentally importa...
Published: December, 2015

Abstract: The involvement of specific nutrients in epigenetic gene regulation is a possible mechanism underlying nutrition-directed phenotypic alteration. Ho... Read more »

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True MicroChIP kit
A highly conserved NF-κB-responsive enhancer is critical for thymic...
Published: December, 2015

Abstract: Autoimmune regulator (Aire) has a unique expression pattern in thymic medullary epithelial cells (mTECs), in which it plays a critical role in the ... Read more »

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Antibody IP-Star Compact
Oxidative DNA damage in mouse sperm chromosomes: Size matters.
Published: December, 2015

Abstract: Normal embryo and foetal development as well as the health of the progeny are mostly dependent on gamete nuclear integrity. In the present study, i... Read more »

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Antibody
Transient generalized glucocorticoid hypersensitivity
Published: December, 2015

Abstract: BACKGROUND: Transient generalized glucocorticoid hypersensitivity is a rare disorder characterized by increased tissue sensitivity to glucocortico... Read more »

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Antibody
The Cytoplasmic Region of Plasmodium falciparum SURFIN4.2 Is Requir...
Published: December, 2015

Abstract: Background: Plasmodium, the causative agent of malaria, exports many proteins to the surface of the infected red blood cell (iRBC) in order to mo... Read more »

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Antibody
Dynamic changes in histone modifications precede de novo DNA methyl...
Published: December, 2015

Abstract: Erasure and subsequent reinstatement of DNA methylation in the germline, especially at imprinted CpG islands (CGIs), is crucial to embryogenesis in... Read more »

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Antibody True MicroChIP kit
Brg1 coordinates multiple processes during retinogenesis and is a t...
Published: December, 2015

Abstract: Retinal development requires precise temporal and spatial coordination of cell cycle exit, cell fate specification, cell migration and differentiat... Read more »

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Antibody
Glucocorticoid receptor and nuclear factor kappa-b affect three-dim...
Published: December, 2015

Abstract: BACKGROUND: The impact of signal-dependent transcription factors, such as glucocorticoid receptor and nuclear factor kappa-b, on the three-dimen... Read more »

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Antibody
Epigenetic priming of inflammatory response genes by high glucose i...
Published: November, 2015

Abstract: Cellular metabolism confers wide-spread epigenetic modifications required for regulation of transcriptional networks that determine cellular states... Read more »

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Antibody

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