Publications,References

Non-coding recurrent mutations in chronic lymphocytic leukaemia.
Published: July, 2015

Abstract: Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations determining the clinicobiological behaviour are not full... Read more »

Tags
Antibody

Deciphering the principles that govern mutually exclusive expressio...
Published: July, 2015

Abstract: The product of the Plasmodium falciparum genes clag3.1 and clag3.2 plays a fundamental role in malaria parasite biology by determining solute trans... Read more »

Tags
Antibody

Evaluation of Methyl-Binding Domain Based Enrichment Approaches Rev...
Published: July, 2015

Abstract: Methyl-binding domain (MBD) enrichment followed by deep sequencing (MBD-seq), is a robust and cost efficient approach for methylome-wide associatio... Read more »

Arterial endothelial methylome: differential DNA methylation in ath...
Published: July, 2015

Abstract: BACKGROUND: Atherosclerosis is a heterogeneously distributed disease of arteries in which the endothelium plays an important central role. Spati... Read more »

Tags
MagMeDIP kit

The complex pattern of epigenomic variation between natural yeast s...
Published: July, 2015

Abstract: BACKGROUND: Epigenomic studies on humans and model species have revealed substantial inter-individual variation in histone modification profiles... Read more »

Tags
Antibody

The oncofusion protein FUS-ERG targets key hematopoietic regulators...
Published: July, 2015

Abstract: The ETS transcription factor ERG has been implicated as a major regulator of both normal and aberrant hematopoiesis. In acute myeloid leukemias har... Read more »

Tags
Antibody

Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in ...
Published: July, 2015

Abstract: Endothelial to mesenchymal transition (EndMT) was originally described in heart development where the endocardial endothelial cells that line the a... Read more »

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tum...
Published: July, 2015

Abstract: Sox9 is a transcription factor expressed in most solid tumors. However, the molecular mechanisms underlying Sox9 function during tumorigenesis rema... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

DNA methylation directs functional maturation of pancreatic β cells
Published: July, 2015

Abstract: Pancreatic β cells secrete insulin in response to postprandial increases in glucose levels to prevent hyperglycemia and inhibit insulin secret... Read more »

Tags
Antibody

Regulation of the expression of claudin 23 by the enhancer of zeste...
Published: July, 2015

Abstract: Altered epigenetic mechanisms, similar to gene mutations, contribute to the pathogenesis and molecular heterogeneity of neoplasms, including colore... Read more »

Tags
Bioruptor Chromatin Shearing Bioruptor Plus

Transcription factor p63 bookmarks and regulates dynamic enhancers ...
Published: July, 2015

Abstract: The transcription factor p63 plays a pivotal role in keratinocyte proliferation and differentiation in the epidermis. However, how p63 regulates ep... Read more »

Tags
Antibody

GCDCA down-regulates gene expression by increasing Sp1 binding to t...
Published: July, 2015

Abstract: During the course of cholestatic liver diseases, the toxic effect of bile acids accumulation has been related to the decreased expression of endoth... Read more »

Tags
Bioruptor Cell Lysis

An Insulator Element Located at the Cyclin B1 Interacting Protein 1...
Published: June, 2015

Abstract: Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by ... Read more »

Tags
LowCell ChIP kit

Histone H3.3 is required for endogenous retroviral element silencin...
Published: June, 2015

Abstract: Transposable elements comprise roughly 40% of mammalian genomes. They have an active role in genetic variation, adaptation and evolution through th... Read more »

Tags
Bioruptor Chromatin Shearing

Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively rep...
Published: June, 2015

Abstract: The chromatin-modifying enzyme lysine-specific demethylase 1, KDM1A/LSD1 is involved in maintaining the undifferentiated, malignant phenotype of ne... Read more »

Tags
Bioruptor Chromatin Shearing

Cistrome of the aldosterone-activated mineralocorticoid receptor in...
Published: June, 2015

Abstract: Aldosterone exerts its effects mainly by activating the mineralocorticoid receptor (MR), a transcription factor that regulates gene expression thro... Read more »

Tags
HighCell ChIP kit

Disruption of DNA-methylation-dependent long gene repression in Ret...
Published: June, 2015

Abstract: Disruption of the MECP2 gene leads to Rett syndrome (RTT), a severe neurological disorder with features of autism. MECP2 encodes a methyl-DNA-bindi... Read more »

Regulation of Hox orthologues in the oyster Crassostrea gigas evide...
Published: June, 2015

Abstract: DNA methylation within promoter regions (PRDM) controls vertebrate early gene transcription and thereby development, but is neglected outside this ... Read more »

Tags
Premium Bisulfite Kit

Concurrent whole-genome haplotyping and copy-number profiling of si...
Published: June, 2015

Abstract: Methods for haplotyping and DNA copy-number typing of single cells are paramount for studying genomic heterogeneity and enabling genetic diagnosis.... Read more »

Tags
DNA shearing Bioruptor

Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates w...
Published: June, 2015

Abstract: Pathologic c-Myc expression is frequently detected in human cancers, including Merkel cell carcinoma (MCC), an aggressive skin cancer with no cure ... Read more »

Tags
Bioruptor Chromatin Shearing

Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postm...
Published: June, 2015

Abstract: AIM: In nondividing neurons examine the role of Gadd45b in active 5-methylcytosine (5MC) and 5-hydroxymethylcytosine (5HMC) removal at a gene promo... Read more »

Tags
Antibody

Active human nucleolar organizer regions are interspersed with inac...
Published: June, 2015

Abstract: AIM: The synthesis of rRNA is a key determinant of normal and malignant cell growth and subject to epigenetic regulation. Yet, the epigenomic fe... Read more »

Tags
Antibody 5mC (C15200081)

Citrate modulates lipopolysaccharide-induced monocyte inflammatory ...
Published: June, 2015

Abstract: Citrate, a central component of cellular metabolism, is a widely used anti-coagulant due to its ability to chelate calcium. Adenosine triphosphate ... Read more »

Tags
Antibody LowCell ChIP kit H3K9ac (C15200185)

Gene chip analysis of Arabidopsis thaliana genomic DNA methylation ...
Published: June, 2015

Abstract: OBJECTIVES: To examine the effects of carbendazim on Arabidopsis genomic DNA methylation and gene expression. RESULTS: Carbendazim caused widesprea... Read more »

Tags
DNA shearing Bioruptor Antibody

Yap7 is a transcriptional repressor of nitric oxide oxidase in yeas...
Published: June, 2015

Abstract: Flavohemoglobins are the main detoxifiers of nitric oxide (NO) in bacteria and fungi and are induced in response to nitrosative stress. In fungi, t... Read more »

Tags
Bioruptor Chromatin Shearing

Transcription of Nrdp1 by the androgen receptor is regulated by nuc...
Published: June, 2015

Abstract: Prostate cancer (PCa) progression is regulated by the androgen receptor (AR); however, patients undergoing androgen-deprivation therapy (ADT) for d... Read more »

Tags
Bioruptor Chromatin Shearing

Proteomic analysis of the herpes simplex virus 1 virion protein 16 ...
Published: June, 2015

Abstract: The herpes simplex virus 1 virion protein 16 (VP16) tegument protein forms a transactivation complex with the cellular proteins host cell factor 1 ... Read more »

Tags
Bioruptor

A SNP in the HTT promoter alters NF-κB binding and is a bidirection...
Published: June, 2015

Abstract: Cis-regulatory variants that alter gene expression can modify disease expressivity, but none have previously been identified in Huntington disease ... Read more »

Tags
Bioruptor Chromatin Shearing HighCell ChIP kit

A localized nucleolar DNA damage response facilitates recruitment o...
Published: June, 2015

Abstract: DNA double-strand breaks (DSBs) are repaired by two main pathways: nonhomologous end-joining and homologous recombination (HR). Repair pathway choi... Read more »

Tags
Antibody CRISPR Cas9 (C15200203)

Allele-specific binding of ZFP57 in the epigenetic regulation of im...
Published: May, 2015

Abstract: BACKGROUND: Selective maintenance of genomic epigenetic imprints during pre-implantation development is required for parental origin-specific ex... Read more »

Tags
Antibody

Publications

Events