Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Ly...
Published: December, 2015

Abstract: The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted gene... Read more »

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Antibody
Valproic acid exposure leads to upregulation and increased promoter...
Published: December, 2015

Abstract: Valproic acid (VPA) is a widely used antiepileptic drug and first-line treatment in bipolar disorder, although the mechanisms underlying its therap... Read more »
DNA methylation profiling: comparison of genome-wide sequencing met...
Published: December, 2015

Abstract: AIMS: To compare the performance of four sequence-based and one microarray methods for DNA methylation profiling. METHODS: DNA from two cell l... Read more »

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MagMeDIP kit Antibody 5mC (C15200081)
Methionine-dependent histone methylation at developmentally importa...
Published: December, 2015

Abstract: The involvement of specific nutrients in epigenetic gene regulation is a possible mechanism underlying nutrition-directed phenotypic alteration. Ho... Read more »

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True MicroChIP kit
A highly conserved NF-κB-responsive enhancer is critical for thymic...
Published: December, 2015

Abstract: Autoimmune regulator (Aire) has a unique expression pattern in thymic medullary epithelial cells (mTECs), in which it plays a critical role in the ... Read more »

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Antibody IP-Star Compact
Oxidative DNA damage in mouse sperm chromosomes: Size matters.
Published: December, 2015

Abstract: Normal embryo and foetal development as well as the health of the progeny are mostly dependent on gamete nuclear integrity. In the present study, i... Read more »

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Antibody
Transient generalized glucocorticoid hypersensitivity
Published: December, 2015

Abstract: BACKGROUND: Transient generalized glucocorticoid hypersensitivity is a rare disorder characterized by increased tissue sensitivity to glucocortico... Read more »

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Antibody
The Cytoplasmic Region of Plasmodium falciparum SURFIN4.2 Is Requir...
Published: December, 2015

Abstract: Background: Plasmodium, the causative agent of malaria, exports many proteins to the surface of the infected red blood cell (iRBC) in order to mo... Read more »

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Antibody
Dynamic changes in histone modifications precede de novo DNA methyl...
Published: December, 2015

Abstract: Erasure and subsequent reinstatement of DNA methylation in the germline, especially at imprinted CpG islands (CGIs), is crucial to embryogenesis in... Read more »

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Antibody True MicroChIP kit
Brg1 coordinates multiple processes during retinogenesis and is a t...
Published: December, 2015

Abstract: Retinal development requires precise temporal and spatial coordination of cell cycle exit, cell fate specification, cell migration and differentiat... Read more »

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Antibody
Glucocorticoid receptor and nuclear factor kappa-b affect three-dim...
Published: December, 2015

Abstract: BACKGROUND: The impact of signal-dependent transcription factors, such as glucocorticoid receptor and nuclear factor kappa-b, on the three-dimen... Read more »

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Antibody
Epigenetic priming of inflammatory response genes by high glucose i...
Published: November, 2015

Abstract: Cellular metabolism confers wide-spread epigenetic modifications required for regulation of transcriptional networks that determine cellular states... Read more »

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Antibody
Evidence for Epigenetic Regulation of Pro-Inflammatory Cytokines, I...
Published: November, 2015

Abstract: While Post Traumatic Stress Disorder (PTSD) is associated with immune dysfunction, the underlying mechanisms remain unclear. Studies suggest a role... Read more »

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MagMeDIP kit Article alert
Pyruvate kinase isoform switching and hepatic metabolic reprogrammi...
Published: November, 2015

Abstract: The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) elicits dose-dependent hepatotoxicity that includes fat accumulation, infl... Read more »

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Microplex Library Preparation kit Article alert
Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses...
Published: November, 2015

Abstract: Oct-1 (POU2f1) and Oct-2 (POU2f2) are members of the POU family of transcription factors. They recognize the same DNA sequence but fulfil distinct ... Read more »

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Chromatin Shearing
Hepatic DNA hydroxymethylation is site-specifically altered by chro...
Published: November, 2015

Abstract: PURPOSE: Global DNA hydroxymethylation is markedly decreased in human cancers, including hepatocellular carcinoma, which is associated with chro... Read more »
Selective targeting of the BRG/PB1 bromodomains impairs embryonic a...
Published: November, 2015

Abstract: Mammalian SWI/SNF [also called Brg/Brahma-associated factors (BAFs)] are evolutionarily conserved chromatin-remodeling complexes regulating gene tr... Read more »

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Antibody
Occupancy of RNA Polymerase II Phosphorylated on Serine 5 (RNAP S5P...
Published: November, 2015

Abstract: Regulation of gene transcription in varicella-zoster virus (VZV), a ubiquitous human neurotropic alphaherpesvirus, requires coordinated binding of ... Read more »

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Antibody
Progressive Chromatin Condensation and H3K9 Methylation Regulate th...
Published: November, 2015

Abstract: Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes a... Read more »

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IP-Star Compact
Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancer...
Published: November, 2015

Abstract: Histone H3K36 trimethylation (H3K36me3) is frequently lost in multiple cancer types, identifying it as an important therapeutic target. Here we ide... Read more »

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Antibody
Complete Genome Sequences of Four Escherichia coli ST95 Isolates fr...
Published: November, 2015

Abstract: Finished genome sequences are presented for four Escherichia coli strains isolated from bloodstream infections at San Francisco General Hospital. T... Read more »
CRISPR-Mediated Gene Targeting of Human Induced Pluripotent Stem Cells
Published: November, 2015

Abstract: CRISPR/Cas9 nuclease systems can create double-stranded DNA breaks at specific sequences to efficiently and precisely disrupt, excise, mutate, inse... Read more »

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Antibody
Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Te...
Published: November, 2015

Abstract: Molecular mechanisms underlying terminal differentiation of B cells into plasma cells are major determinants of adaptive immunity but remain only p... Read more »

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Antibody
The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cyc...
Published: November, 2015

Abstract: Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle. Differentiation and the alteration of this balance can result ... Read more »

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Antibody
Spatial Interplay between Polycomb and Trithorax Complexes Controls...
Published: November, 2015

Abstract: Trithorax group (TrxG) and Polycomb group (PcG) proteins are two mutually antagonistic chromatin modifying complexes, however, how they together me... Read more »

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Antibody
Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Pre...
Published: November, 2015

Abstract: Genetic and epigenetic alterations have been identified as to contribute directly or indirectly to the generation of transitional cell carcinoma of... Read more »

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Antibody
HNF1β drives glutathione (GSH) synthesis underlying intrinsic carbo...
Published: October, 2015

Abstract: Chemoresistance to platinum-based antineoplastic agents is a consistent feature among ovarian carcinomas; however, whereas high-grade serous carcin... Read more »

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Bioruptor Article alert
NeuroD1 reprograms chromatin and transcription factor landscapes to...
Published: October, 2015

Abstract: Abstract Cell fate specification relies on the action of critical transcription factors that become available at distinct stages of embryonic deve... Read more »

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Bioruptor Chromatin Shearing Bioruptor Plus
Epigenetic role of CCAAT box-binding transcription factor NF-Y on I...
Published: October, 2015

Abstract: Nuclear factor Y (NF-Y) is a histone substitute protein that specifically binds to the CCAAT box of the target genes and thereby promotes their reg... Read more »

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Article alert
A gene expression signature identifying transient DNMT1 depletion a...
Published: October, 2015

Abstract: Many human tumors show aberrant activation of a group of germline-specific genes, termed cancer-germline (CG) genes, several of which appear to exe... Read more »

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Antibody Article alert

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