Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Genome-wide DNA methylation analysis in Graves' disease.
Published: January, 2015

Abstract: As an autoimmune disease, Graves' disease (GD) is associated with many genetic and environmental risk factors. Although the exact mechanism remains... Read more »

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DNA shearing Bioruptor Antibody
Dynamic Regulation of Schwann Cell Enhancers after Peripheral Nerve...
Published: January, 2015

Abstract: Myelination of the peripheral nervous system is required for axonal function and long term stability. After peripheral nerve injury, Schwann cells ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
An ultra-low-input native ChIP-seq protocol for genome-wide profili...
Published: January, 2015

Abstract: Combined chromatin immunoprecipitation and next-generation sequencing (ChIP-seq) has enabled genome-wide epigenetic profiling of numerous cell line... Read more »

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Bioruptor Antibody H3K27me3 (C15410069)
Ultra-low-input native ChIP-seq for rare cell populations
Published: January, 2015

Abstract: Combined chromatin immunoprecipitation and next-generation sequencing (ChIP-seq) has enabled genome-wide epigenetic profiling of numerous cell line... Read more »

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Antibody H3K27me3 (C15410069)
A vlincRNA participates in senescence maintenance by relieving H2AZ...
Published: January, 2015

Abstract: Non-coding RNAs (ncRNAs) play major roles in proper chromatin organization and function. Senescence, a strong anti-proliferative process and a majo... Read more »

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Antibody H3K4me3 (C15410003)
USP7 COOPERATES WITH SCML2 TO REGULATE THE ACTIVITY OF PRC1.
Published: January, 2015

Abstract: USP7 is a protein deubiquitinase with an essential role in development. Here, we provide evidence that USP7 regulates the activity of the Polycomb ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Alternative splicing regulates the expression of G9A and SUV39H2 me...
Published: January, 2015

Abstract: Alternative splicing is the main source of proteome diversity. Here, we have investigated how alternative splicing affects the function of two huma... Read more »

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Bioruptor Cell Lysis Western Blot
Linked circadian outputs control elongation growth and flowering in...
Published: January, 2015

Abstract: Clock-regulated pathways coordinate the response of many developmental processes to changes in photoperiod and temperature. We model two of the bes... Read more »

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Bioruptor Chromatin Shearing
PU.1 Opposes IL-7-Dependent Proliferation of Developing B Cells wit...
Published: January, 2015

Abstract: Deletion of genes encoding the E26 transformation-specific transcription factors PU.1 and Spi-B in B cells (CD19-CreΔPB mice) leads to impaired B c... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Transcription-coupled recruitment of human CHD1 and CHD2 influences...
Published: January, 2015

Abstract: Background CHD1 and CHD2 chromatin remodeling enzymes play important roles in development, cancer and differentiation. At a molecular level, the m... Read more »

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Bioruptor Chromatin Shearing Bioruptor Plus
Development of a unique epigenetic signature during in vivo Th17 di...
Published: January, 2015

Abstract: Activated naive CD4(+) T cells are highly plastic cells that can differentiate into various T helper (Th) cell fates characterized by the expressio... Read more »

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MethylCap
Recurrent ETNK1 mutations in atypical chronic myeloid leukemia.
Published: January, 2015

Abstract: Despite the recent identification of recurrent SETBP1 mutations in atypical chronic myeloid leukemia (aCML), a complete description of the somatic ... Read more »

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DNA shearing Bioruptor Bioruptor Plus
The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for ...
Published: January, 2015

Abstract: The persistence of a latent reservoir containing transcriptionally silent, but replication-competent, integrated provirus is a serious challenge to... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Mining for viral fragments in methylation enriched sequencing data
Published: January, 2015

Abstract: Most next generation sequencing experiments generate more data than is required for the experimental set up. For example, methyl-CpG binding domain... Read more »

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MethylCap
The histone demethylase enzyme KDM3A is a key estrogen receptor reg...
Published: January, 2015

Abstract: Endocrine therapy has successfully been used to treat estrogen receptor (ER)-positive breast cancer, but this invariably fails with cancers becomin... Read more »

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IP-Star Antibody IP-Star Compact
Htt CAG repeat expansion confers pleiotropic gains of mutant huntin...
Published: January, 2015

Abstract: The CAG repeat expansion in the Huntington's disease gene HTT extends a polyglutamine tract in mutant huntingtin that enhances its ability to facil... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis ChIP-seq
Genetic evidence for ecological divergence in kokanee salmon.
Published: January, 2015

Abstract: The evolution of locally adapted phenotypes among populations that experience divergent selective pressures is a central mechanism for generating a... Read more »

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DNA shearing Bioruptor
Thyroid hormone receptor sumoylation is required for preadipocyte d...
Published: January, 2015

Abstract: Thyroid hormone and thyroid hormone receptor (TR) play an essential role in metabolic regulation. However, the role of TR in adipogenesis is not es... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Phosphorylation of TET proteins is regulated via O-GlcNAcylation by...
Published: January, 2015

Abstract: TET proteins oxidize 5-methylcytosine (mC) to 5-hydroxymethylcytosine (hmC), 5-formylcytosine (fC) and 5-carboxylcytosine (caC) and thus provide a ... Read more »

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Bioruptor Cell Lysis Mass Spectrometry Bioruptor Plus
STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response ...
Published: January, 2015

Abstract: Evidence is accumulating for the existence of a STAT2/IRF9-dependent, STAT1-independent IFNα signaling pathway. However, no detailed insight exists... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
NTR1 is required for transcription elongation checkpoints at altern...
Published: January, 2015

Abstract: The interconnection between transcription and splicing is a subject of intense study. We report that Arabidopsis homologue of spliceosome disassemb... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Locus-Specific Targeting to the X Chromosome Revealed by the RNA In...
Published: January, 2015

Abstract: CTCF is a master regulator that plays important roles in genome architecture and gene expression. How CTCF is recruited in a locus-specific manner ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR RNA Shearing
Genome-wide methylation analysis in Silver-Russell syndrome patients.
Published: January, 2015

Abstract: Silver-Russell syndrome (SRS) is a clinically heterogeneous disorder characterised by severe in utero growth restriction and poor postnatal growth,... Read more »

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DNA shearing Bioruptor
TRIM28 Represses Transcription of Endogenous Retroviruses in Neural...
Published: January, 2015

Abstract: TRIM28 is a corepressor that mediates transcriptional silencing by establishing local heterochromatin. Here, we show that deletion of TRIM28 in neu... Read more »

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Antibody
iRNA-seq: computational method for genome-wide assessment of acute ...
Published: January, 2015

Abstract: RNA-seq is a sensitive and accurate technique to compare steady-state levels of RNA between different cellular states. However, as it does not prov... Read more »

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Antibody
The human urine virome in association with urinary tract infections
Published: January, 2015

Abstract: While once believed to represent a sterile environment, the human urinary tract harbors a unique cellular microbiota. We sought to determine whethe... Read more »

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DNA shearing Bioruptor
Fast and discriminative CoSYPS detection system of viable Salmonell...
Published: January, 2015

Abstract: In this study, the complete CoSYPS Path Food workflow including all steps, namely swab sample enrichment, SYBR®Green qPCR detection of Salmonella s... Read more »

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Master Mix
STAT3 acts through pre-existing nucleosome-depleted regions bound b...
Published: January, 2015

Abstract: BACKGROUND: Transient induction of the Src oncoprotein in a non-transformed breast cell line can initiate an epigenetic switch to a cancer cell via... Read more »

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Bioruptor Chromatin Shearing
Amplification of pico-scale DNA mediated by bacterial carrier DNA f...
Published: January, 2015

Abstract: BACKGROUND: Chromatin-Immunoprecipitation coupled with deep sequencing (ChIP-seq) is used to map transcription factor occupancy and generate epigen... Read more »

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DNA shearing Bioruptor
Histone H3 Phosphorylation in GBM: a New Rational to Guide the Use ...
Published: January, 2015

Abstract: Histones post-translational modifications (PTMs) are crucial components of diverse processes that modulate chromatin. Among the histones PTMs, the ... Read more »

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Bioruptor MeDIP kit

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