Publications,References

Impact of Thyroid Hormones on Estrogen Receptor α-Dependent Transcr...
Published: March, 2015

Abstract: Elevated levels of thyroid hormones (TH) reduce estradiol (E2)-dependent female sexual behavior. E2 stimulates progesterone receptor (Pgr) and oxyt... Read more »

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Bioruptor Chromatin Shearing

Genome-wide CRISPR screen in a mouse model of tumor growth and meta...
Published: March, 2015

Abstract: Genetic screens are powerful tools for identifying genes responsible for diverse phenotypes. Here we describe a genome-wide CRISPR/Cas9-mediated lo... Read more »

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Antibody CRISPR Cas9 (C15200203)

Adipose tissue-derived stem cells from obese subjects contribute to...
Published: March, 2015

Abstract: Obesity, through low-grade inflammation, can drive insulin-resistance and type 2 diabetes. While infiltration of adipose tissue (AT) with mononucle... Read more »

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Bioruptor Chromatin Shearing

The nuclear receptor nr4a1 controls CD8 T cell development through ...
Published: March, 2015

Abstract: The NR4A nuclear receptor family member Nr4a1 is strongly induced in thymocytes undergoing selection, and has been shown to control the development... Read more »

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Bioruptor Chromatin Shearing

Chromatin fibers are formed by heterogeneous groups of nucleosomes ...
Published: March, 2015

Abstract: Nucleosomes help structure chromosomes by compacting DNA into fibers. To gain insight into how nucleosomes are arranged in vivo, we combined quanti... Read more »

Genome wide expression profiling of p53 regulated miRNAs in neurobl...
Published: March, 2015

Abstract: Restoration of the antitumor activity of p53 could offer a promising approach for the treatment of neuroblastoma. MicroRNAs (miRNAs) are important ... Read more »

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Bioruptor Chromatin Shearing

Human disease modeling reveals integrated transcriptional and epige...
Published: March, 2015

Abstract: The mechanisms by which transcription factor haploinsufficiency alters the epigenetic and transcriptional landscape in human cells to cause disease... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody Microplex Library Preparation kit

H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C prom...
Published: March, 2015

Abstract: DNA replication is a tightly regulated process that initiates from multiple replication origins and leads to the faithful transmission of the genet... Read more »

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Bioruptor Chromatin Shearing

Childhood allergic asthma is associated with increased IL-13 and FO...
Published: March, 2015

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Bioruptor Chromatin Shearing

Identification of FOXM1 as a therapeutic target in B-cell lineage a...
Published: March, 2015

Abstract: Despite recent advances in the cure rate of acute lymphoblastic leukaemia (ALL), the prognosis for patients with relapsed ALL remains poor. Here we... Read more »

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Bioruptor Chromatin Shearing

Use of the CRISPR/Cas9 system as an intracellular defense against H...
Published: March, 2015

Abstract: To combat hostile viruses, bacteria and archaea have evolved a unique antiviral defense system composed of clustered regularly interspaced short pa... Read more »

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Antibody CRISPR Cas9 (C15200203)

PW1/Peg3 expression regulates key properties that determine mesoang...
Published: March, 2015

Abstract: Mesoangioblasts are vessel-associated progenitor cells that show therapeutic promise for the treatment of muscular dystrophy. Mesoangioblasts have ... Read more »

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Bioruptor Chromatin Shearing

AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetylt...
Published: March, 2015

Abstract: BACKGROUND: Histone acetyltransferase complex NuA4 and histone variant exchanging complex SWR1 are two chromatin modifying complexes which act coop... Read more »

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Bioruptor Chromatin Shearing

Nuclear matrix binding protein SMAR1 regulates T-cell differentiati...
Published: March, 2015

Abstract: Asthma is a complex airway allergic disease involving the interplay of various cell types, cytokines, and transcriptional factors. Though many fact... Read more »

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Bioruptor Chromatin Shearing

Genome-wide mapping reveals conservation of promoter DNA methylatio...
Published: March, 2015

Abstract: It is well-known that environment influences DNA methylation, however, the extent of heritable DNA methylation variation following animal domestica... Read more »

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DNA shearing Bioruptor Antibody

Bacterial Infection Remodels the DNA Methylation Landscape of Human...
Published: March, 2015

Abstract: DNA methylation is thought to be robust to environmental perturbations on a short time scale. Here, we challenge that view by demonstrating that th... Read more »

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Bioruptor Chromatin Shearing ChIP-seq IP-Star IP-Star Compact

An inducible lentiviral guide RNA platform enables the identificati...
Published: March, 2015

Abstract: The CRISPR/Cas9 technology enables the introduction of genomic alterations into almost any organism; however, systems for efficient and inducible g... Read more »

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Antibody CRISPR Cas9 (C15200203)

Population differentiation determined from putative neutral and div...
Published: March, 2015

Abstract: Twelve eulachon (Thaleichthys pacificus, Osmeridae) populations ranging from Cook Inlet, Alaska and along the west coast of North America to the Co... Read more »

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DNA shearing Bioruptor Bioruptor Plus

An inducible lentiviral guide RNA platform enables the identificati...
Published: March, 2015

Abstract: The CRISPR/Cas9 technology enables the introduction of genomic alterations into almost any organism; however, systems for efficient and inducible g... Read more »

Tags
Antibody CRISPR Cas9 (C15200203)

Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by...
Published: March, 2015

Abstract: Head morphogenesis requires complex signal relays to enable precisely coordinated proliferation, migration, and patterning. Here, we demonstrate th... Read more »

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Bioruptor Chromatin Shearing

Rad51-mediated replication fork reversal is a global response to ge...
Published: March, 2015

Abstract: Replication fork reversal protects forks from breakage after poisoning of Topoisomerase 1. We here investigated fork progression and chromosomal br... Read more »

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Bioruptor Chromatin Shearing

The histone chaperone complex HIR maintains nucleosome occupancy an...
Published: March, 2015

Abstract: Chromatin organization is essential for coordinated gene expression, genome stability, and inheritance of epigenetic information. The main componen... Read more »

Exon-intron circular RNAs regulate transcription in the nucleus.
Published: March, 2015

Abstract: Noncoding RNAs (ncRNAs) have numerous roles in development and disease, and one of the prominent roles is to regulate gene expression. A vast numbe... Read more »

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Bioruptor Chromatin Shearing RNA Shearing

Essential role of the iron-sulfur cluster binding domain of the pri...
Published: March, 2015

Abstract: DNA primase catalyzes de novo synthesis of a short RNA primer that is further extended by replicative DNA polymerases during initiation of DNA repl... Read more »

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Bioruptor Chromatin Shearing

The Integrator complex controls the termination of transcription at...
Published: March, 2015

Abstract: Complexes containing INTS3 and either NABP1 or NABP2 were initially characterized in DNA damage responses, but their biochemical function remained ... Read more »

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Bioruptor Cell Lysis Western Blot

LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during...
Published: March, 2015

Abstract: Emerging studies document the roles of long non-coding RNAs (LncRNAs) in regulating gene expression at chromatin level but relatively less is known... Read more »

Definition of the transcription factor TdIF1 consensus-binding sequ...
Published: March, 2015

Abstract: TdIF1 was originally identified as a protein that directly binds to terminal deoxynucleotidyltransferase, TdT. Through in vitro selection assays (S... Read more »

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LowCell ChIP kit

The DREAM complex promotes gene body H2A.Z for target repression.
Published: March, 2015

Abstract: The DREAM (DP, Retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell cycle genes, but its mechanism of a... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Genome-wide redistribution of BRD4 binding sites in transformation ...
Published: March, 2015

Abstract: Hutchinson-Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

Zinc finger independent genome-wide binding of Sp2 potentiates recr...
Published: March, 2015

Abstract: Transcription factors are grouped into families based on sequence similarity within functional domains, particularly DNA-binding domains. The Speci... Read more »

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Microplex Library Preparation kit

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