Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Long intronic GAA repeats causing Friedreich ataxia impede transcri...
Published: April, 2010

Abstract: Friedreich ataxia is a degenerative disease caused by deficiency of the protein frataxin (FXN). An intronic expansion of GAA triplets in the FXN-en... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Autonomous silencing of the imprinted Cdkn1c gene in stem cells
Published: April, 2010

Abstract: Parent-of-origin specific expression of imprinted genes relies on the differential DNA methylation of specific genomic regions. Differentially meth... Read more »

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Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003) Histone ChIP kit
The male-determining gene SRY is a hybrid of DGCR8 and SOX3, and is...
Published: April, 2010

Abstract: In mammals, sex is determined by the presence or absence of the Y chromosome that bears a male-dominant sex-determining gene SRY, which switches th... Read more »
Regulation of photoreceptor gene expression by the retinal homeobox...
Published: March, 2010

Abstract: The retinal homeobox (Rx) gene product is essential for eye development. However little is known about its molecular function. It has been demonstr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
DNA methylome of familial breast cancer identifies distinct profile...
Published: March, 2010

Abstract: It is now understood that epigenetic alterations occur frequently in sporadic breast carcinogenesis, but little is known about the epigenetic alter... Read more »

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MeDIP kit
Distinct factors control histone variant H3.3 localization at speci...
Published: March, 2010

Abstract: The incorporation of histone H3 variants has been implicated in the epigenetic memory of cellular state. Using genome editing with zinc-finger nucl... Read more »

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Chromatin Shearing ChIP-qPCR
DNA methylation regulates adenosine A(2A) receptor cell surface exp...
Published: March, 2010

Abstract: Adenosine A(2A) receptors (A(2A)Rs) appear to play important roles in inflammation and in certain diseases of the nervous system. Pharmacological m... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
Splicing factor Spf30 assists exosome-mediated gene silencing in fi...
Published: March, 2010

Abstract: Heterochromatin assembly in fission yeast relies on the processing of cognate noncoding RNAs by both the RNA interference and the exosome degradati... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Dr1 (NC2) is present at tRNA genes and represses their transcriptio...
Published: March, 2010

Abstract: Dr1 (also known as NC2beta) was identified as a repressor of RNA polymerase (pol) II transcription. It was subsequently shown to inhibit pol III tr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Bone morphogenetic protein-7 inhibits proximal tubular epithelial c...
Published: March, 2010

Abstract: Bone morphogenetic protein-7 (BMP-7) improves outcome in animal models of fibrotic renal disease by opposing transforming growth factor beta1 (TGF-... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Use of pJANUS-02-001 as a calibrator plasmid for Roundup Ready soyb...
Published: March, 2010

Abstract: Owing to the labelling requirements of food and feed products containing materials derived from genetically modified organisms, quantitative detect... Read more »

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Master Mix
Increased efficacy for in-house validation of real-time PCR GMO det...
Published: March, 2010

Abstract: To improve the efficacy of the in-house validation of GMO detection methods (DNA isolation and real-time PCR, polymerase chain reaction), a study w... Read more »

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Master Mix
Viral induction of the zinc finger antiviral protein is IRF3-depend...
Published: February, 2010

Abstract: The zinc finger antiviral protein (ZAP) is an interferon-stimulated gene that restricts the replication of retroviruses, alphaviruses, and filoviru... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The lysyl oxidases LOX and LOXL2 are necessary and sufficient to re...
Published: February, 2010

Abstract: Hypoxia has been shown to promote tumor metastasis and lead to therapy resistance. Recent work has demonstrated that hypoxia represses E-cadherin e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Targets of the Tal1 transcription factor in erythrocytes: E2 ubiqui...
Published: February, 2010

Abstract: The Tal1 transcription factor is essential for the development of the hematopoietic system and plays a role during definitive erythropoiesis in the... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Alternative splicing of the histone demethylase LSD1/KDM1 contribut...
Published: February, 2010

Abstract: A variety of chromatin remodeling complexes are thought to orchestrate transcriptional programs that lead neuronal precursors from earliest commitm... Read more »

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Antibody
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyeloc...
Published: February, 2010

Abstract: Many different molecular mechanisms have been associated with PML-RARalpha-dependent transformation of hematopoietic progenitors. Here, we identifi... Read more »

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IP-Star Antibody RARalpha (C15310155)
Chromatin remodeling by imitation switch (ISWI) class ATP-dependent...
Published: February, 2010

Abstract: ATP-dependent chromatin remodeling complexes rearrange nucleosomes by altering the position of DNA around the histone octamer. Although chromatin r... Read more »

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Antibody
AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.
Published: February, 2010

Abstract: Transcriptome profiling has become a routine tool in biology. For Arabidopsis (Arabidopsis thaliana), the Affymetrix ATH1 expression array is most ... Read more »

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Bioruptor Chromatin Shearing Antibody LowCell ChIP kit
Antiinflammatory properties of a plant-derived nonsteroidal, dissoc...
Published: February, 2010

Abstract: Compound A (CpdA), a plant-derived phenyl aziridine precursor, was recently characterized as a fully dissociated nonsteroidal antiinflammatory agen... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an ac...
Published: February, 2010

Abstract: The papillomavirus life cycle parallels keratinocyte differentiation in stratifying epithelia. We have previously shown that the human papillomavir... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Potential role of estrogen in regulation of the insulin-like growth...
Published: January, 2010

Abstract: The selective estrogen receptor modulator, tamoxifen, has been shown to reduce DNA methylation at Insulin-like growth factor 2/H19 differentially m... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic chromatin states uniquely define the developmental plast...
Published: January, 2010

Abstract: Heritable epigenetic signatures are proposed to serve as an important regulatory mechanism in lineage fate determination. To investigate this, we p... Read more »

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Bioruptor Chromatin Shearing
Early-life experience reduces excitation to stress-responsive hypot...
Published: January, 2010

Abstract: Increased sensory input from maternal care attenuates neuroendocrine and behavioral responses to stress long term and results in a lifelong phenoty... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Activation of Cdc6 by MyoD is associated with the expansion of quie...
Published: January, 2010

Abstract: MyoD is a transcriptional factor that is required for the differentiation of muscle stem cells (satellite cells). In this study, we describe a prev... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects st...
Published: January, 2010

Abstract: The biology of the alpha subunits of hypoxia-inducible factors (HIFalpha) has expanded from their role in angiogenesis to their current position in... Read more »

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LowCell ChIP kit
Cardiac signaling genes exhibit unexpected sequence diversity in sp...
Published: January, 2010

Abstract: Sporadic heart failure is thought to have a genetic component, but the contributing genetic events are poorly defined. Here, we used ultra-high-thr... Read more »
Unlocking short read sequencing for metagenomics.
Published: January, 2010

Abstract: BACKGROUND: Different high-throughput nucleic acid sequencing platforms are currently available but a trade-off currently exists between the cost a... Read more »

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DNA shearing Bioruptor
Polycomb target genes are silenced in multiple myeloma.
Published: January, 2010

Abstract: Multiple myeloma (MM) is a genetically heterogeneous disease, which to date remains fatal. Finding a common mechanism for initiation and progressio... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
A comprehensive map of insulator elements for the Drosophila genome.
Published: January, 2010

Abstract: Insulators are DNA sequences that control the interactions among genomic regulatory elements and act as chromatin boundaries. A thorough understand... Read more »

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Bioruptor Chromatin Shearing

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