Publications,References

TF-ChIP Method for Tissue-Specific Gene Targets.
Published: March, 2019

Abstract: Chromatin immunoprecipitation (ChIP) is an assay developed in order to define the dynamic nature of transcription processes. This method has been w... Read more »

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Bioruptor

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prost...
Published: March, 2019

Abstract: Androgen deprivation therapy for prostate cancer (PCa) benefits patients with early disease, but becomes ineffective as PCa progresses to a castrat... Read more »

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Antibody

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Defici...
Published: March, 2019

Abstract: Increasingly effective therapies targeting the androgen receptor have paradoxically promoted the incidence of neuroendocrine prostate cancer (NEPC)... Read more »

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Antibody

A critical regulator of Bcl2 revealed by systematic transcript disc...
Published: March, 2019

Abstract: Normal T-cell differentiation requires a complex regulatory network which supports a series of maturation steps, including lineage commitment, T-ce... Read more »

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Antibody Microplex Library Preparation kit

Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in ...
Published: March, 2019

Abstract: Developing and adult tissues use different cis-regulatory elements. Although DNA at some decommissioned embryonic enhancers is hypomethylated in ad... Read more »

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Antibody

DMSO induces drastic changes in human cellular processes and epigen...
Published: March, 2019

Abstract: Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity in the 1960s, later, the FDA classified DMSO in the ... Read more »

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MagMeDIP kit

The role of TCF3 as potential master regulator in blastemal Wilms t...
Published: March, 2019

Abstract: Wilms tumors are the most common type of pediatric kidney tumors. While the overall prognosis for patients is favorable, especially tumors that exh... Read more »

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Antibody

lncRNA KHPS1 Activates a Poised Enhancer by Triplex-Dependent Recru...
Published: March, 2019

Abstract: Transcription of the proto-oncogene SPHK1 is regulated by KHPS1, an antisense RNA that activates SPHK1 expression by forming a triple-helical RNA-D... Read more »

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Antibody

Transcriptome-wide dynamics of extensive m6A mRNA methylation durin...
Published: March, 2019

Abstract: Malaria pathogenesis results from the asexual replication of Plasmodium falciparum within human red blood cells, which relies on a precisely timed ... Read more »

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Bioruptor Microplex Library Preparation kit

R-Loops Enhance Polycomb Repression at a Subset of Developmental Re...
Published: March, 2019

Abstract: R-loops are three-stranded nucleic acid structures that form during transcription, especially over unmethylated CpG-rich promoters of active genes.... Read more »

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Antibody

Maintenance of MYC expression promotes de novo resistance to BET br...
Published: March, 2019

Abstract: The BET bromodomain protein BRD4 is a chromatin reader that regulates transcription, including in cancer. In prostate cancer, specifically, the ant... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

Ezh2 controls development of natural killer T cells, which cause sp...
Published: March, 2019

Abstract: BACKGROUND: Natural killer T (NKT) cells express a T-cell receptor that recognizes endogenous and environmental glycolipid antigens. Several subset... Read more »

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Antibody

Genetic, Inflammatory, and Epithelial Cell Differentiation Factors ...
Published: March, 2019

Abstract: Eosinophilic esophagitis (EoE) is a chronic, food-driven allergic disease resulting in eosinophilic esophageal inflammation. We recently found that... Read more »

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IP-Star Compact

The epigenetic basis for the impaired ability of adult murine retin...
Published: March, 2019

Abstract: The epigenetic plasticity of amphibian retinal pigment epithelium (RPE) allows them to regenerate the entire retina, a trait known to be absent in ... Read more »

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Antibody IP-Star Compact True MicroChIP kit

Chromatin activity at GWAS loci identifies T cell states driving co...
Published: March, 2019

Abstract: Complex immune disease variants are enriched in active chromatin regions of T cells and macrophages. However, whether these variants function in sp... Read more »

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Bioruptor iDeal ChIP-seq Kit for Histones

MicroRNAs and Transplantation.
Published: March, 2019

Abstract: miRNAs, ∼20 to 22 nucleotide single-stranded RNA species that play a pivotal role in the regulation of protein-coding genes, are emerging as ro... Read more »

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CATS

NF-κB p65 dimerization and DNA-binding is important for inflammator...
Published: March, 2019

Abstract: Increasing evidence shows that many transcription factors execute important biologic functions independent from their DNA-binding capacity. The NF-... Read more »

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Microplex Library Preparation kit

H3K27me3 is an epigenetic barrier while KDM6A overexpression improv...
Published: March, 2019

Abstract: Aberrant epigenetic reprogramming is a major factor of developmental failure of cloned embryos. Histone H3 lysine 27 trimethylation (H3K27me3), a h... Read more »

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Antibody

Long-term evaluation of AAV-CRISPR genome editing for Duchenne musc...
Published: March, 2019

Abstract: Duchenne muscular dystrophy (DMD) is a monogenic disorder and a candidate for therapeutic genome editing. There have been several recent reports of... Read more »

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CRISPR

One-step generation of modular CAR-T cells with AAV-Cpf1.
Published: March, 2019

Abstract: Immune-cell engineering opens new capabilities for fundamental immunology research and immunotherapy. We developed a system for efficient generatio... Read more »

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CRISPR

Genomewide analysis of 6-methyladenine DNA in peripheral blood mono...
Published: March, 2019

Abstract: AIM: The aim of this paper is to explore the expression of 6-methyladenine (6mA) DNA and to elucidate its gene regulation role in systemic lupus er... Read more »

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Antibody

The alternative reality of plant mitochondrial DNA
Published: March, 2019

Abstract: Plant mitochondrial genomes are usually assembled and displayed as circular maps based on the widely-held assumption that circular genome molecules... Read more »

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Megaruptor

Differential regulation of RNA polymerase III genes during liver re...
Published: February, 2019

Abstract: Mouse liver regeneration after partial hepatectomy involves cells in the remaining tissue synchronously entering the cell division cycle. We have u... Read more »

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Microplex Library Preparation kit

A critical but divergent role of PRDM14 in human primordial germ ce...
Published: February, 2019

Abstract: PRDM14 is a crucial regulator of mouse primordial germ cells (mPGC), epigenetic reprogramming and pluripotency, but its role in the evolutionarily ... Read more »

Environmental Toxicant Induced Epigenetic Transgenerational Inherit...
Published: February, 2019

Abstract: Prostate diseases include prostate cancer, which is the second most common male neoplasia, and benign prostatic hyperplasia (BPH), which affects ap... Read more »

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Antibody

CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoiet...
Published: February, 2019

Abstract: In this study, we demonstrate that, among all five CBX Polycomb proteins, only CBX7 possesses the ability to control self-renewal of human hematopo... Read more »

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Antibody Microplex Library Preparation kit

Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Mic...
Published: February, 2019

Abstract: The Ebola virus glycoprotein (EBOV-GP) forms GP-containing microvesicles, so-called virosomes, which are secreted from GP-expressing cells. However... Read more »

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Antibody

EZH2 is overexpressed in transitional preplasmablasts and is involv...
Published: February, 2019

Abstract: Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using m... Read more »

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Antibody IPure kit IP-Star Compact True MicroChIP kit iDeal ChIP-seq Kit for Transcription Factors

A cell cycle-coordinated Polymerase II transcription compartment en...
Published: February, 2019

Abstract: Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed until the mid-blastu... Read more »

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Antibody

Crosstalk Between Glucocorticoid Receptor and Early-growth Response...
Published: February, 2019

Abstract: The brain-derived neurotrophic factor (BDNF) is a key player in brain functions such as synaptic plasticity, stress, and behavior. Its gene structu... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

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