Publications,References

Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy du...
Published: October, 2018

Abstract: NF-E2-related factor 2 (NRF2) transcription factor has a fundamental role in cell homeostasis maintenance as one of the master regulators of oxidat... Read more »

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Antibody

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone ...
Published: October, 2018

Abstract: Proteomic analysis of histones has shown that they are subject to a superabundance of acylations, which extend far beyond acetylation, to include: ... Read more »

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IPure kit

The Itaconate Pathway Is a Central Regulatory Node Linking Innate I...
Published: October, 2018

Abstract: Sepsis involves simultaneous hyperactivation of the immune system and immune paralysis, leading to both organ dysfunction and increased susceptibil... Read more »

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Antibody Bioruptor Plus

Multi-axial self-organization properties of mouse embryonic stem ce...
Published: October, 2018

Abstract: The emergence of multiple axes is an essential element in the establishment of the mammalian body plan. This process takes place shortly after impl... Read more »

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Antibody

Long-read sequencing identified a causal structural variant in an e...
Published: September, 2018

Abstract: Background: For a proportion of individuals judged clinically to have a recessive Mendelian disease, only one heterozygous pathogenic variant can b... Read more »

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Megaruptor

Gap junction protein Connexin-43 is a direct transcriptional regula...
Published: September, 2018

Abstract: Connexins are the primary components of gap junctions, providing direct links between cells under many physiological processes. Here, we demonstrat... Read more »

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Antibody

Histone variant H2A.Z deposition and acetylation directs the canoni...
Published: September, 2018

Abstract: A fundamental as yet incompletely understood feature of Notch signal transduction is a transcriptional shift from repression to activation that dep... Read more »

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Antibody

Development of PCR screening assays focused on genecoding sequences...
Published: September, 2018

Abstract: For the detection of genetically modifed organisms (GMO), screening is the frst step used to determine if a GMO or its derived products are present... Read more »

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Master Mix

Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to t...
Published: September, 2018

Abstract: Protein arginine methyltransferase 6 (PRMT6) catalyzes asymmetric dimethylation of histone H3 at arginine 2 (H3R2me2a). This mark has been reported... Read more »

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Microplex Library Preparation kit

UCP1 transrepression in Brown Fat in vivo and mineralocorticoid rec...
Published: September, 2018

Abstract: OBJECTIVES: The mineralocorticoid receptor (MR), a hormone-activated transcription factor, besides its role in controlling hydroelectrolytic homeos... Read more »

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Antibody HighCell ChIP kit

Genome-wide analysis of DNA methylation to identify genes and pathw...
Published: September, 2018

Abstract: DNA methylation is an epigenetic modification, which is important for gene expression regulation. Although genome-wide DNA methylation studies have... Read more »

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MagMeDIP kit

Adenovirus E1A Activation Domain Regulates H3 Acetylation Affecting...
Published: September, 2018

Abstract: How histone acetylation promotes transcription is not clearly understood. Here, we confirm an interaction between p300 and the adenovirus 2 large E... Read more »

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Antibody

Impact of human sepsis on CCCTC-binding factor associated monocyte ...
Published: September, 2018

Abstract: BACKGROUND: Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for... Read more »

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Antibody

MIWI2 targets RNAs transcribed from piRNA-dependent regions to driv...
Published: September, 2018

Abstract: Argonaute/Piwi proteins can regulate gene expression via RNA degradation and translational regulation using small RNAs as guides. They also promote... Read more »

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Antibody

The Atlantic salmon (Salmo salar) antimicrobial peptide cathelicidi...
Published: September, 2018

Abstract: Chemical signals are a key element of host-parasite interactions. In marine ecosystems, obligate ectoparasites, such as sea lice, use chemical cues... Read more »

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CATS

NGS analysis of total small non coding RNAs from low input RNA from...
Published: September, 2018

Abstract: Circulating miRNAs are favored for biomarker candidates as they can reflect tissue specific miRNA dysregulation in disease contexts. Moreover, they... Read more »

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CATS

FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis e...
Published: September, 2018

Abstract: The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In ... Read more »

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ChIP-seq

Dot1 promotes H2B ubiquitination by a methyltransferase-independent...
Published: September, 2018

Abstract: The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome. H... Read more »

Mapping molecular landmarks of human skeletal ontogeny and pluripot...
Published: September, 2018

Abstract: Tissue-specific gene expression defines cellular identity and function, but knowledge of early human development is limited, hampering application ... Read more »

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Antibody LowCell ChIP kit

Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryo...
Published: September, 2018

Abstract: Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have id... Read more »

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Antibody

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purki...
Published: September, 2018

Abstract: In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of sy... Read more »

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Antibody

Transcription Elongation Can Affect Genome 3D Structure.
Published: September, 2018

Abstract: How transcription affects genome 3D organization is not well understood. We found that during influenza A (IAV) infection, rampant transcription ra... Read more »

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Antibody

Folic acid supplementation alters the DNA methylation profile and i...
Published: September, 2018

Abstract: Folic acid (FA) supplementation may protect from obesity and insulin resistance, the effects and mechanism of FA on chronic high-fat-diet-induced o... Read more »

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MagMeDIP kit

RNA Sequencing and Pathway Analysis Identify Important Pathways Inv...
Published: September, 2018

Abstract: A growing number of histone modifiers are involved in human neurodevelopmental disorders, suggesting that proper regulation of chromatin state is e... Read more »

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Antibody

Genome-wide measurement of local nucleosome array regularity and sp...
Published: September, 2018

Abstract: The nature of chromatin as regular succession of nucleosomes has gained iconic status. However, since most nucleosomes in metazoans are poorly posi... Read more »

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iDeal Library Preparation Kit

Differential DNA methylation of potassium channel KCa3.1 and immune...
Published: August, 2018

Abstract: Bacillus Calmette-Guérin (BCG) is the only licensed vaccine for tuberculosis (TB) and induces highly variable protection against pulmonary d... Read more »

High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation r...
Published: August, 2018

Abstract: While suppression of specific genes through aberrant promoter methylation contributes to different diseases including organ fibrosis, gene-specific... Read more »

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OneDay ChIP Kit

Polycomb repressive complex 1 shapes the nucleosome landscape but n...
Published: August, 2018

Abstract: Polycomb group (PcG) proteins are transcriptional repressors that play important roles in regulating gene expression during animal development. In ... Read more »

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Antibody

Lamin B1 mapping reveals the existence of dynamic and functional eu...
Published: August, 2018

Abstract: Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic... Read more »

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Beads

Progenitor Hyperpolarization Regulates the Sequential Generation of...
Published: August, 2018

Abstract: During corticogenesis, ventricular zone progenitors sequentially generate distinct subtypes of neurons, accounting for the diversity of neocortical... Read more »

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Antibody

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