Publications,References

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modu...
Published: January, 2015

Abstract: Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whet... Read more »

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Bioruptor Tissue Homogenization

Curcumin inhibits anchorage-independent growth of HT29 human colon ...
Published: January, 2015

Abstract: Colorectal cancer remains the most prevalent malignancy in humans. The impact of epigenetic alterations on the development of this complex disease ... Read more »

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DNA shearing Bioruptor

Reduced Expression of MYC Increases Longevity and Enhances Healthspan.
Published: January, 2015

Abstract: MYC is a highly pleiotropic transcription factor whose deregulation promotes cancer. In contrast, we find that Myc haploinsufficient (Myc(+/-)) mic... Read more »

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Bioruptor Chromatin Shearing

Ligand-dependent enhancer activation regulated by topoisomerase-I a...
Published: January, 2015

Abstract: The discovery that enhancers are regulated transcription units, encoding eRNAs, has raised new questions about the mechanisms of their activation. ... Read more »

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Bioruptor Chromatin Shearing

A small peptide derived from p53 linker region can resume the apopt...
Published: January, 2015

Abstract: One of the most important tumor suppression functions of p53 is its ability to induce apoptosis. iASPP is an inhibitory member of the ASPP protein ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Stable X Chromosome Reactivation in Female Human Induced Pluripoten...
Published: January, 2015

Abstract: In placental mammals, balanced expression of X-linked genes is accomplished by X chromosome inactivation (XCI) in female cells. In humans, random X... Read more »

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Antibody

Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumor...
Published: January, 2015

Abstract: Ovarian clear-cell carcinoma (OCCC) is an aggressive form of ovarian cancer with high ARID1A mutation rates. Here we present a mutant mouse model o... Read more »

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Bioruptor Chromatin Shearing

Age dependent changes in the LPS induced transcriptome of bovine de...
Published: January, 2015

Abstract: BackgroundBy comparing fibroblasts collected from animals at 5-months or 16-months of age we have previously found that the cultures from older ani... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Pharmacologically relevant doses of valproate upregulate CD20 expre...
Published: January, 2015

Abstract: Background Epigenetic code modifications by histone deacetylase inhibitors (HDACi) have been proposed as potential new therapies for lymphoid mal... Read more »

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Bioruptor Cell Lysis Western Blot

Embryonic stem cell differentiation requires full length Chd1.
Published: January, 2015

Abstract: The modulation of chromatin dynamics by ATP-dependent chromatin remodeling factors has been recognized as an important mechanism to regulate the ba... Read more »

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Antibody H3K4me3 (C15410003)

Emergence of differentially regulated pathways associated with the ...
Published: January, 2015

Abstract: BackgroundRegional specificity allows different skin regions to exhibit different characteristics, enabling complementary functions to make effecti... Read more »

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LowCell ChIP kit

Dppa3 expression is critical for generation of fully reprogrammed i...
Published: January, 2015

Abstract: Reprogramming of mouse somatic cells into induced pluripotent stem cells (iPSCs) often generates partially reprogrammed iPSCs (pre-iPSCs), low-grad... Read more »

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Bioruptor Chromatin Shearing

Genome-wide DNA methylation analysis in Graves' disease.
Published: January, 2015

Abstract: As an autoimmune disease, Graves' disease (GD) is associated with many genetic and environmental risk factors. Although the exact mechanism remains... Read more »

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DNA shearing Bioruptor Antibody

Dynamic Regulation of Schwann Cell Enhancers after Peripheral Nerve...
Published: January, 2015

Abstract: Myelination of the peripheral nervous system is required for axonal function and long term stability. After peripheral nerve injury, Schwann cells ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

An ultra-low-input native ChIP-seq protocol for genome-wide profili...
Published: January, 2015

Abstract: Combined chromatin immunoprecipitation and next-generation sequencing (ChIP-seq) has enabled genome-wide epigenetic profiling of numerous cell line... Read more »

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Bioruptor Antibody H3K27me3 (C15410069)

Ultra-low-input native ChIP-seq for rare cell populations
Published: January, 2015

Abstract: Combined chromatin immunoprecipitation and next-generation sequencing (ChIP-seq) has enabled genome-wide epigenetic profiling of numerous cell line... Read more »

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Antibody H3K27me3 (C15410069)

A vlincRNA participates in senescence maintenance by relieving H2AZ...
Published: January, 2015

Abstract: Non-coding RNAs (ncRNAs) play major roles in proper chromatin organization and function. Senescence, a strong anti-proliferative process and a majo... Read more »

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Antibody H3K4me3 (C15410003)

USP7 COOPERATES WITH SCML2 TO REGULATE THE ACTIVITY OF PRC1.
Published: January, 2015

Abstract: USP7 is a protein deubiquitinase with an essential role in development. Here, we provide evidence that USP7 regulates the activity of the Polycomb ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Alternative splicing regulates the expression of G9A and SUV39H2 me...
Published: January, 2015

Abstract: Alternative splicing is the main source of proteome diversity. Here, we have investigated how alternative splicing affects the function of two huma... Read more »

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Bioruptor Cell Lysis Western Blot

Linked circadian outputs control elongation growth and flowering in...
Published: January, 2015

Abstract: Clock-regulated pathways coordinate the response of many developmental processes to changes in photoperiod and temperature. We model two of the bes... Read more »

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Bioruptor Chromatin Shearing

PU.1 Opposes IL-7-Dependent Proliferation of Developing B Cells wit...
Published: January, 2015

Abstract: Deletion of genes encoding the E26 transformation-specific transcription factors PU.1 and Spi-B in B cells (CD19-CreΔPB mice) leads to impaired B c... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

Transcription-coupled recruitment of human CHD1 and CHD2 influences...
Published: January, 2015

Abstract: Background CHD1 and CHD2 chromatin remodeling enzymes play important roles in development, cancer and differentiation. At a molecular level, the m... Read more »

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Bioruptor Chromatin Shearing Bioruptor Plus

Development of a unique epigenetic signature during in vivo Th17 di...
Published: January, 2015

Abstract: Activated naive CD4(+) T cells are highly plastic cells that can differentiate into various T helper (Th) cell fates characterized by the expressio... Read more »

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MethylCap

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia.
Published: January, 2015

Abstract: Despite the recent identification of recurrent SETBP1 mutations in atypical chronic myeloid leukemia (aCML), a complete description of the somatic ... Read more »

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DNA shearing Bioruptor Bioruptor Plus

The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for ...
Published: January, 2015

Abstract: The persistence of a latent reservoir containing transcriptionally silent, but replication-competent, integrated provirus is a serious challenge to... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Mining for viral fragments in methylation enriched sequencing data
Published: January, 2015

Abstract: Most next generation sequencing experiments generate more data than is required for the experimental set up. For example, methyl-CpG binding domain... Read more »

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MethylCap

The histone demethylase enzyme KDM3A is a key estrogen receptor reg...
Published: January, 2015

Abstract: Endocrine therapy has successfully been used to treat estrogen receptor (ER)-positive breast cancer, but this invariably fails with cancers becomin... Read more »

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IP-Star Antibody IP-Star Compact

Htt CAG repeat expansion confers pleiotropic gains of mutant huntin...
Published: January, 2015

Abstract: The CAG repeat expansion in the Huntington's disease gene HTT extends a polyglutamine tract in mutant huntingtin that enhances its ability to facil... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis ChIP-seq

Genetic evidence for ecological divergence in kokanee salmon.
Published: January, 2015

Abstract: The evolution of locally adapted phenotypes among populations that experience divergent selective pressures is a central mechanism for generating a... Read more »

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DNA shearing Bioruptor

Thyroid hormone receptor sumoylation is required for preadipocyte d...
Published: January, 2015

Abstract: Thyroid hormone and thyroid hormone receptor (TR) play an essential role in metabolic regulation. However, the role of TR in adipogenesis is not es... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

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