Publications,References

Genome-wide redistribution of BRD4 binding sites in transformation ...
Published: March, 2015

Abstract: Hutchinson-Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

Zinc finger independent genome-wide binding of Sp2 potentiates recr...
Published: March, 2015

Abstract: Transcription factors are grouped into families based on sequence similarity within functional domains, particularly DNA-binding domains. The Speci... Read more »

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Microplex Library Preparation kit

The histone chaperone complex HIR *maintains *nucleosome occupancy ...
Published: March, 2015

Abstract: Chromatin organization is essential for coordinated gene expression, genome stability, and inheritance of epigenetic information. Main components o... Read more »

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Bioruptor Chromatin Shearing

DNase I hypersensitivity analysis of the mouse brain and retina ide...
Published: February, 2015

Abstract: Background The brain, spinal cord, and neural retina comprise the central nervous system (CNS) of vertebrates. Understanding the regulatory mechan... Read more »

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LowCell ChIP kit

DNA methylome and transcriptome sequencing in human ovarian granulo...
Published: February, 2015

Abstract: Diminished ovarian function occurs early and is a primary cause for age-related decline in female fertility; however, its underlying mechanism rema... Read more »

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MethylCap

FUBP1: a new protagonist in splicing regulation of the DMD gene.
Published: February, 2015

Abstract: We investigated the molecular mechanisms for in-frame skipping of DMD exon 39 caused by the nonsense c.5480T>A mutation in a patient with Becker mu... Read more »

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Bioruptor Chromatin Shearing

Functional characterization of IgA-targeted bacterial taxa from und...
Published: February, 2015

Abstract: To gain insights into the interrelationships among childhood undernutrition, the gut microbiota, and gut mu- cosal immune/barrier function, we puri... Read more »

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DNA shearing Bioruptor

Genome-wide profiling of DNA methylation provides insights into epi...
Published: February, 2015

Abstract: DNA methylation is an important epigenetic modification that regulates development of plants and mammals. To investigate the roles of DNA methylati... Read more »

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DNA shearing Bioruptor

Epigenome mapping reveals distinct modes of gene regulation and wid...
Published: February, 2015

Abstract: Transcription factor fusion proteins can transform cells by inducing global changes of the transcriptome, often creating a state of oncogene addict... Read more »

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Antibody H3K4me3 (C15410003) H3K27me3 (C15410195)

A Meier-Gorlin Syndrome Mutation Impairs the ORC1-Nucleosome Associ...
Published: February, 2015

Abstract: Recent studies have identified several genetic mutations within the BAH domain of human Origin Recognition Complex subunit 1 (hORC1BAH), including ... Read more »

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Bioruptor

MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic...
Published: February, 2015

Abstract: The microcephalin gene (MCPH1) [also known as inhibitor of human telomerase reverse transcriptase (hTERT) expression] is a tumor suppressor gene th... Read more »

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Bioruptor Chromatin Shearing Antibody

Silica nanoparticles induce oxidative stress, inflammation, and end...
Published: February, 2015

Abstract: Abstract: Despite the widespread application of silica nanoparticles (SiNPs) in industrial, commercial, and biomedical fields, their response ... Read more »

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Bioruptor

Genome-wide analysis of DNA methylation in photoperiod- and thermo-...
Published: February, 2015

Abstract: BACKGROUND: Epigenetic modifications play important roles in the regulation of plant development. DNA methylation is an important epigenetic modifi... Read more »

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MagMeDIP kit

Intermediate DNA methylation is a conserved signature of genome reg...
Published: February, 2015

Abstract: The role of intermediate methylation states in DNA is unclear. Here, to comprehensively identify regions of intermediate methylation and their quan... Read more »

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DNA shearing Bioruptor

Epigenetic and transcriptional determinants of the human breast.
Published: February, 2015

Abstract: While significant effort has been dedicated to the characterization of epigenetic changes associated with prenatal differentiation, relatively litt... Read more »

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DNA shearing Bioruptor

Stabilization of nontoxic Aβ-oligomers: insights into the mechanism...
Published: February, 2015

Abstract: The extracellular accumulation of amyloid β (Aβ) peptides is characteristic of Alzheimer's disease (AD). However, formation of diffusible, oligomer... Read more »

Reprogramming of the ERRα and ERα target gene landscape triggers ta...
Published: February, 2015

Abstract: Endocrine treatment regimens for breast cancer that target the estrogen receptor-α (ERα) are effective, but acquired resistance remains a limiting ... Read more »

A pro-apoptotic function of iASPP by stabilizing p300 and CBP throu...
Published: February, 2015

Abstract: The p53 family and its cofactors are potent inducers of apoptosis and form a barrier to cancer. Here, we investigated the impact of the supposedly ... Read more »

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Antibody

MEK guards proteome stability and inhibits tumor-suppressive amyloi...
Published: February, 2015

Abstract: Signaling through RAS/MAP kinase pathway is central to biology. ERK has long been perceived as the only substrate for MEK. Here, we report that HSF... Read more »

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Bioruptor

p73 engages A2B receptor signalling to prime cancer cells to chemot...
Published: February, 2015

Abstract: Tumour cells often acquire the ability to escape cell death, a key event leading to the development of cancer. In almost half of all human cancers,... Read more »

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Bioruptor Chromatin Shearing

Phylogenomics of Phrynosomatid Lizards: Conflicting Signals from Se...
Published: February, 2015

Abstract: Sequence capture and restriction site associated DNA sequencing (RADseq) are popular methods for obtaining large numbers of loci for phylogenetic a... Read more »

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DNA shearing Bioruptor

The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Act...
Published: February, 2015

Abstract: The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate tran... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K27ac (C15410174)

Circulating nucleic acids damage DNA of healthy cells by integratin...
Published: February, 2015

Abstract: Whether nucleic acids that circulate in blood have any patho-physiological functions in the host have not been explored.We report here that far fro... Read more »

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DNA shearing Bioruptor

Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine...
Published: February, 2015

Abstract: Ten eleven translocation (Tet) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcyt... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody

Genipin as a novel chemical activator of EBV lytic cycle.
Published: February, 2015

Abstract: Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus that causes acute infection and establishes life-long latency. EBV causes several human c... Read more »

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Bioruptor Cell Lysis Western Blot

Genome-wide and single-cell analyses reveal a context dependent rel...
Published: February, 2015

Abstract: Genome-wide distribution of histone H3K18 and H3K27 acetyltransferases, CBP (CREBBP) and p300 (EP300), is used to map enhancers and promoters, but ... Read more »

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Antibody

Discovery of transcription factors and regulatory regions driving i...
Published: February, 2015

Abstract: Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound t... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Increased HDAC3 and decreased miRNA-130a expression in PBMCs throu...
Published: February, 2015

Abstract: The study was performed to investigate the molecular mechanism for SCI patients. The interaction between miRNA-130a and HDAC was demonstrated in PB... Read more »

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Bioruptor Chromatin Shearing

Direct entry by RNase E is a major pathway for the degradation and ...
Published: February, 2015

Abstract: Escherichia coli endoribonuclease E has a major influence on gene expression. It is essential for the maturation of ribosomal and transfer RNA as w... Read more »

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Bioruptor Bioruptor Plus RNA Shearing

Tat predominantly associates with host promoter elements in HIV-1-i...
Published: February, 2015

Abstract: UNLABELLED: HIV-1 Tat is a multifunctional regulatory protein that, in addition to its primary function of transactivating viral transcription, als... Read more »

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Bioruptor Chromatin Shearing

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