Publications,References

Telomerase regulates MYC-driven oncogenesis independent of its reve...
Published: May, 2015

Abstract: Constitutively active MYC and reactivated telomerase often coexist in cancers. While reactivation of telomerase is thought to be essential for repl... Read more »

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Bioruptor Chromatin Shearing

Clinical application of whole-genome sequencing to inform treatment...
Published: May, 2015

Abstract: The treatment of drug-resistant tuberculosis cases is challenging, as drug options are limited, and the existing diagnostics are inadequate. Whole-... Read more »

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Bioruptor

Sensitive detection of chromatin-altering polymorphisms reveals aut...
Published: May, 2015

Abstract: Most disease associations detected by genome-wide association studies (GWAS) lie outside coding genes, but very few have been mapped to causal regu... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

Regulation of chromatin accessibility and Zic binding at enhancers ...
Published: May, 2015

Abstract: To identify chromatin mechanisms of neuronal differentiation, we characterized chromatin accessibility and gene expression in cerebellar granule ne... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Microplex Library Preparation kit

A lncRNA regulates alternative splicing via establishment of a spli...
Published: May, 2015

Abstract: Alternative pre-mRNA splicing is a highly cell type-specific process essential to generating protein diversity. However, the mechanisms responsible... Read more »

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Bioruptor Chromatin Shearing Antibody H3K27me3 (C15410195)

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activate...
Published: May, 2015

Abstract: Technologies that enable targeted manipulation of epigenetic marks could be used to precisely control cell phenotype or interrogate the relationshi... Read more »

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Bioruptor Chromatin Shearing

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic ...
Published: May, 2015

Abstract: DNA methylation is a key epigenetic modification involved in regulating gene expression and maintaining genomic integrity. Here we inactivated all ... Read more »

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Antibody 5mC (C15200081)

C2H2 zinc finger proteins greatly expand the human regulatory lexicon.
Published: May, 2015

Abstract: Cys2-His2 zinc finger (C2H2-ZF) proteins represent the largest class of putative human transcription factors. However, for most C2H2-ZF proteins it... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Linking the aryl hydrocarbon receptor with altered DNA methylation ...
Published: May, 2015

Abstract: Successfully fighting infection requires a properly tuned immune system. Recent epidemiological studies link exposure to pollutants that bind the a... Read more »

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Bioruptor Chromatin Shearing

Global regulation of heterochromatin spreading by Leo1.
Published: May, 2015

Abstract: Heterochromatin plays important roles in eukaryotic genome regulation. However, the repressive nature of heterochromatin combined with its propensi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Development of microsatellite primers in the protected species Viol...
Published: May, 2015

Abstract: PREMISE OF THE STUDY: Viola elatior (Violaceae) is a Eurasian perennial plant species in which French populations are threatened by anthropogenic p... Read more »

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DNA shearing Bioruptor

The interaction of mycobacterial protein Rv2966c with host chromati...
Published: April, 2015

Abstract: To effectively modulate the gene expression within an infected mammalian cell, the pathogen Mycobacterium tuberculosis would need to bring about ep... Read more »

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Bioruptor Chromatin Shearing IP-Star Antibody IP-Star Compact

Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogen...
Published: April, 2015

Abstract: Hepatocellular carcinoma (HCC) is a worldwide threat to public health, especially in China, where chronic hepatitis B virus (HBV) infection is foun... Read more »

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Bioruptor Chromatin Shearing

Th17 cells transdifferentiate into regulatory T cells during resolu...
Published: April, 2015

Abstract: Inflammation is a beneficial host response to infection but can contribute to inflammatory disease if unregulated. The Th17 lineage of T helper (Th... Read more »

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DNA shearing Bioruptor

The preRC protein ORCA organizes heterochromatin by assembling hist...
Published: April, 2015

Abstract: Heterochromatic domains are enriched with repressive histone marks, including histone H3 lysine 9 methylation, written by lysine methyltransferases... Read more »

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Chromatin Shearing

Identification of Critical Elements for Regulation of Inorganic Pyr...
Published: April, 2015

Abstract: Cytosolic inorganic pyrophosphatase plays an important role in the cellular metabolism by hydrolyzing inorganic pyrophosphate (PPi) formed as a by-... Read more »

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Antibody

Transcriptional activation by the thyroid hormone receptor through ...
Published: April, 2015

Abstract: A bimodal switch model is widely used to describe transcriptional regulation by the thyroid hormone receptor (TR). In this model, the unliganded TR... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I
Published: April, 2015

Abstract: Spt6 has many roles in transcription initiation and elongation by RNA polymerase (Pol) II. These effects are mediated through interactions with his... Read more »

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Bioruptor Chromatin Shearing

Suppression of Interferon β gene transcription by inhibitors of Bro...
Published: April, 2015

Abstract: Polo-Like Kinase (PLK) inhibitors, such as BI-2536, have been reported to suppress interferon β (IFNβ) gene transcription induced by ligands that a... Read more »

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Bioruptor Chromatin Shearing

RAR/RXR binding dynamics distinguish pluripotency from differentiat...
Published: April, 2015

Abstract: In mouse embryonic cells, ligand-activated retinoic acid receptors (RARs) play a key role in inhibiting pluripotency-maintaining genes and activati... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Intrinsic retroviral reactivation in human preimplantation embryos ...
Published: April, 2015

Abstract: Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections, and comprise nearly 8% of the human genome. The most recently acquire... Read more »

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Bioruptor Chromatin Shearing

Opposite expression of CYP51A1 and its natural antisense transcript...
Published: April, 2015

Abstract: Cytochrome P450 family member CYP51A1 is a key enzyme in cholesterol biosynthesis whose deregulation is implicated in numerous diseases, including ... Read more »

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Antibody H3K4me3 (C15410003)

Deciphering the role of Polycomb Repressive Complex 1 (PRC1) varian...
Published: April, 2015

Abstract: Polycomb Group (PcG) proteins play important roles in regulating developmental phase transitions in plants; however, little is known about the role... Read more »

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Antibody H3K27me3 (C15410069)

Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-...
Published: April, 2015

Abstract: Upland cotton is a model for polyploid crop domestication and transgenic improvement. Here we sequenced the allotetraploid Gossypium hirsutum L. ac... Read more »

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DNA shearing Bioruptor

The chromatin Remodeler CHD8 is required for activation of progeste...
Published: April, 2015

Abstract: While the importance of gene enhancers in transcriptional regulation is well established, the mechanisms and the protein factors that determine enh... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation o...
Published: April, 2015

Abstract: DNA methylation is tightly regulated throughout mammalian development, and altered DNA methylation patterns are a general hallmark of cancer. The m... Read more »

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Antibody

Genome-Wide Analysis of Phosphorylated PhoP Binding to Chromosomal ...
Published: April, 2015

Abstract: UNLABELLED: The PhoPR two-component signal transduction system controls one of three responses activated by Bacillus subtilis to adapt to phosphate... Read more »

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Bioruptor Chromatin Shearing

High-throughput and quantitative assessment of enhancer activity in...
Published: April, 2015

Abstract: Cell-type specific regulation of gene expression requires the activation of promoters by distal genomic elements defined as enhancers. The identifi... Read more »

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DNA shearing Bioruptor

Transcriptional co-repressor function of the hippo pathway transduc...
Published: April, 2015

Abstract: YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway. However, whether... Read more »

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Bioruptor Chromatin Shearing

DNA methylation and gene expression profiles show novel regulatory ...
Published: April, 2015

Abstract: BACKGROUND: Alcohol is a well-known risk factor for hepatocellular carcinoma (HCC), but the mechanisms underlying the alcohol-related hepatocarcino... Read more »

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MeDIP kit

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