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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Genome-wide DNA methylation profiling with MeDIP-seq using archived...
Published: July, 2016
Abstract: Background In utero and early-life experienced environmental exposures are suggested to play an important role in many multifactorial diseases pote... Read more »
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Bioruptor IP-Star MeDIP kit IPure kit
Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epider...
Published: July, 2016
Abstract: The genome-wide localization and function of endogenous Dnmt3a and Dnmt3b in adult stem cells are unknown. Here, we show that in human epidermal st... Read more »
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Antibody
Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organoge...
Published: July, 2016
Abstract: Renal hypoplasia is a common cause of pediatric renal failure and several adult-onset diseases. Recent studies have associated a variant of the OSR... Read more »
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Antibody
Induction of cell differentiation activates transcription of the Sa...
Published: July, 2016
Abstract: The Sarco/Endoplasmic Reticulum Ca2+ -ATPases (SERCAs), pump Ca2+ into the endoplasmic reticulum lumen modulating cytosolic Ca2+ concentrations to ... Read more »
H3K4 acetylation, H3K9 acetylation and H3K27 methylation in breast ...
Published: July, 2016
Abstract: AIM: Here, we investigated how the St Gallen breast molecular subtypes displayed distinct histone H3 profiles. PATIENTS & METHODS: 192 bre... Read more »
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Antibody IP-Star Compact
Combined analysis of DNA methylome and transcriptome reveal novel c...
Published: July, 2016
Abstract: Subclinical mastitis is a widely spread disease of lactating cows. Its major pathogen is Staphylococcus aureus (S. aureus). In this study, we perfo... Read more »
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Antibody
Characterization of the replication timing program of 6 human model...
Published: July, 2016
Abstract: During the S-phase, the DNA replication process is finely orchestrated and regulated by two programs: the spatial program that determines where rep... Read more »
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IP-Star Compact
5-hydroxymethylcytosine marks postmitotic neural cells in the adult...
Published: July, 2016
Abstract: The epigenetic mark 5-hydroxymethylcytosine (5hmC) is a cytosine modification that is abundant in the central nervous system of mammals and which r... Read more »
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Antibody
H4K5 histone acetylation of BRG1 is associated with heroin administ...
Published: July, 2016
Abstract: Diacetylmorphine hydrochloride (heroin) addiction is a chronic relapsing brain disorder that is a heavy public health burden worldwide. Brm/SWI2-re... Read more »
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IP-Star Compact
MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML
Published: July, 2016
Abstract: Homeobox genes are known to be key factors in leukemogenesis. Although the TALE family homeodomain factor Meis1 has been linked to malignancy, a ro... Read more »
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Antibody
Regulation of the DNA Methylation Landscape in Human Somatic Cell R...
Published: July, 2016
Abstract: Reprogramming to pluripotency after overexpression of OCT4, SOX2, KLF4, and MYC is accompanied by global genomic and epigenomic changes. Histone mo... Read more »
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IP-Star Antibody
Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloprolifer...
Published: July, 2016
Abstract: Myeloproliferative neoplasm (MPN) patients frequently show co-occurrence of JAK2-V617F and mutations in epigenetic regulator genes, including EZH2.... Read more »
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True MicroChIP kit
Epigenetic silencing of serine protease HTRA1 drives polyploidy
Published: July, 2016
Abstract: BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observ... Read more »
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Antibody
Regulatory Interaction between the Cellular Restriction Factor IFI1...
Published: July, 2016
Abstract: A key player in the intrinsic resistance against human cytomegalovirus (HCMV) is the interferon-γ-inducible protein 16 (IFI16), which behaves... Read more »
DNA demethylation of inflammasome-associated genes is enhanced in p...
Published: July, 2016
Abstract: BACKGROUND: Inflammasomes are cytosolic multiprotein complexes in macrophages. They assemble after infection- or stress-associated stimuli, activa... Read more »
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LowCell ChIP kit
RAB25 expression is epigenetically downregulated in oral and oropha...
Published: July, 2016
Abstract: Oral and oropharyngeal squamous cell carcinoma (OOSCC) have a low survival rate, mainly due to metastasis to the regional lymph nodes. For optimal ... Read more »
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MethylCap
Methylation of the Sox9 and Oct4 promoters and its correlation with...
Published: July, 2016
Abstract: Sox9 and Oct4 are two important regulatory factors involved in mammalian development. Sox9, a member of the group E Sox transcription factor family... Read more »
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Antibody
UMI-4C for quantitative and targeted chromosomal contact profiling
Published: July, 2016
Abstract: We developed a targeted chromosome conformation capture (4C) approach that uses unique molecular identifiers (umis) to derive high-complexity quant... Read more »
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Bioruptor
miR-125b-1 is repressed by histone modifications in breast cancer c...
Published: July, 2016
Abstract: PURPOSE: Downregulation of miR-125b-1 is associated with poor prognosis in breast cancer patients. In this work we investigated the effect of hi... Read more »
Premalignant SOX2 overexpression in the fallopian tubes of ovarian ...
Published: July, 2016
Abstract: Current screening methods for ovarian cancer can only detect advanced disease. Earlier detection has proved difficult because the molecular precurs... Read more »
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Antibody
The dynamic interactome and genomic targets of Polycomb complexes d...
Published: July, 2016
Abstract: Although the core subunits of Polycomb group (PcG) complexes are well characterized, little is known about the dynamics of these protein complexes ... Read more »
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Bioruptor Antibody
Epigenetic Modifications with DZNep, NaBu and SAHA in Luminal and M...
Published: July, 2016
Abstract: BACKGROUND/AIM: Numerous studies have shown that breast cancer and epigenetic mechanisms have a very powerful interactive relation. The MCF7 cell ... Read more »
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IP-Star Antibody
Differential Incorporation of β-actin as A Component of RNA Polymer...
Published: July, 2016
Abstract: Objective Nuclear actin is involved in transcription regulation by recruitment of histone modifiers and chromatin remodelers to the regulatory... Read more »
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Histone ChIP kit
Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diab...
Published: June, 2016
Abstract: Aims. To conduct a genome-wide DNA methylation in individuals with type 2 diabetes, individuals with prediabetes, and control mixed ancestry indivi... Read more »
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Antibody
Chromatin accessibility maps of chronic lymphocytic leukaemia ident...
Published: June, 2016
Abstract: Chronic lymphocytic leukaemia (CLL) is characterized by substantial clinical heterogeneity, despite relatively few genetic alterations. To provide ... Read more »
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Antibody
Expression of the Parkinson's Disease-Associated Gene Alpha-Synucle...
Published: June, 2016
Abstract: Alpha-synuclein is an abundant neuronal protein which has been associated with physiological processes like synaptic function, neurogenesis, and ne... Read more »
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Antibody
Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Caus...
Published: June, 2016
Abstract: BACKGROUND & AIMS: The polycomb repressive complex 2 (PRC2) regulates differentiation by contributing to repression of gene expression and the... Read more »
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Microplex Library Preparation kit
Molecular and Epigenetic Biomarkers in Luminal Androgen Receptor: A...
Published: June, 2016
Abstract: Read more »
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IP-Star Antibody
Efficiency of methylated DNA immunoprecipitation bisulphite sequenc...
Published: June, 2016
Abstract: We compared four common methods for measuring DNA methylation levels and recommended the most efficient method in terms of cost and coverage. MATE... Read more »
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MagMeDIP kit
Dnmt2/Trdmt1 as Mediator of RNA Polymerase II Transcriptional Activ...
Published: June, 2016
Abstract: Dnmt2/Trdmt1 is a methyltransferase, which has been shown to methylate tRNAs. Deficient mutants were reported to exhibit various, seemingly unrelat... Read more »
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Antibody 5mC (C15200081)

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