Publications,References

A signature motif mediating selective interactions of BCL11A with t...
Published: August, 2013

Abstract: Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restar...
Published: August, 2013

Abstract: Chromatin remodeling is tightly linked to all DNA-transacting activities. To study chromatin remodeling during DNA repair, we established quantitat... Read more »

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Bioruptor Chromatin Shearing

Optical control of mammalian endogenous transcription and epigeneti...
Published: August, 2013

Abstract: The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causa... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A GAA repeat expansion reporter model of Friedreich's ataxia recapi...
Published: August, 2013

Abstract: Friedreich's ataxia (FRDA) is caused by large GAA expansions in intron 1 of the frataxin gene (FXN), which lead to reduced FXN expression through a... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Conserved Regulators of Nucleolar Size Revealed by Global Phenotypi...
Published: August, 2013

Abstract: Regulation of cell growth is a fundamental process in development and disease that integrates a vast array of extra- and intracellular information.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Sexually Dimorphic Genome-Wide Binding of Retinoid X Receptor alpha...
Published: August, 2013

Abstract: Many hepatic functions including lipid metabolism, drug metabolism, and inflammatory responses are regulated in a sex-specific manner due to distin... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

PARP-1 Controls Immunosuppressive Function of Regulatory T Cells by...
Published: August, 2013

Abstract: Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme and transcription factor that is involved in inflammatory response, but its role in T c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

An In-Depth Characterization of the Major Psoriasis Susceptibility ...
Published: August, 2013

Abstract: Psoriasis is an immune-mediated skin disorder that is inherited as a complex genetic trait. Although genome-wide association scans (GWAS) have iden... Read more »

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Antibody

Genome-wide screening identifies Plasmodium chabaudi-induced modifi...
Published: August, 2013

Abstract: Epigenetic reprogramming of host genes via DNA methylation is increasingly recognized as critical for the outcome of diverse infectious diseases, b... Read more »

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Antibody MeDIP kit 5mC (C15200081)

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically...
Published: August, 2013

Abstract: Mutations in the metabolic enzymes isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) are frequently found in glioma, acute myeloid leukemia (AML), mel... Read more »

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Bioruptor Cell Lysis Mass Spectrometry

Systematic Identification of Proteins Binding to Chromatin-Embedded...
Published: August, 2013

Abstract: Chromatin posttranslational modifications (PTMs), including monoubiquitylation of histone H2B on lysine 120 (H2Bub1), play a major role in regulati... Read more »

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Bioruptor Cell Lysis

CDK8-Mediated STAT1-S727 Phosphorylation Restrains NK Cell Cytotoxi...
Published: August, 2013

Abstract: The transcription factor STAT1 is important in natural killer (NK) cells, which provide immediate defense against tumor and virally infected cells.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

WT1 regulates the expression of inhibitory chemokines during heart ...
Published: August, 2013

Abstract: The embryonic epicardium is an important source of cardiovascular precursor cells and paracrine factors that are required for adequate heart format... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mod5 protein binds to tRNA gene complexes and affects local transcr...
Published: August, 2013

Abstract: The tRNA gene-mediated (tgm) silencing of RNA polymerase II promoters is dependent on subnuclear clustering of the tRNA genes, but genetic analysis... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Artd1/Parp1 regulates reprogramming by transcriptional regulation o...
Published: August, 2013

Abstract: The recently established reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by Takahashi and Yamanaka, represents a valuabl... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor...
Published: August, 2013

Abstract: In contrast to its close homolog CDK4, the cell cycle kinase CDK6 is expressed at high levels in lymphoid malignancies. In a model for p185(BCR-ABL... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)

Chromatin-Bound IκBα Regulates a Subset of Polycomb Target Genes in...
Published: August, 2013

Abstract: IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of kerati... Read more »

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Bioruptor

A three-state model for the regulation of telomerase by TERRA and h...
Published: August, 2013

Abstract: Telomeres, the physical ends of eukaryotic chromosomes, are transcribed into telomeric repeat-containing RNA (TERRA), a large non-coding RNA, which... Read more »

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Bioruptor

Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in ...
Published: August, 2013

Abstract: Polycomb Repressive Complex 2 (PRC2) mediates transcriptional silencing by catalyzing histone H3 lysine 27 trimethylation (H3K27me3), but its role ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-...
Published: August, 2013

Abstract: DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA ... Read more »

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DNA shearing Bioruptor MagMeDIP kit Antibody

Histone variant Htz1 promotes histone H3 acetylation to enhance nuc...
Published: August, 2013

Abstract: Nucleotide excision repair (NER) is critical for maintaining genome integrity. How chromatin dynamics are regulated to facilitate this process in c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Nanolipodendrosome-loaded glatiramer acetate and myogenic different...
Published: August, 2013

Abstract: BACKGROND: Muscular dystrophies consist of a number of juvenile and adult forms of complex disorders which generally cause weakness or efficiency d... Read more »

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Bioruptor Liposome Preparation

Quantification of biomass and cell motion in human pluripotent stem...
Published: August, 2013

Abstract: Somatic cell reprogramming to pluripotency requires an immediate increase in cell proliferation and reduction in cell size. It is unknown whether p... Read more »

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Master Mix

Model selection reveals control of cold signalling by evening-phase...
Published: August, 2013

Abstract: Circadian clocks confer advantages by restricting biological processes to certain times of day through the control of specific phased outputs. Cont... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mitochondrial genome linearization is a causative factor for cardio...
Published: August, 2013

Abstract: Aims: Mitofusin (Mfn) 2 redundantly promotes mitochondrial outer membrane tethering and organelle fusion with Mfn1, and uniquely functions as the m... Read more »

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DNA shearing Bioruptor

A role for SIRT2-dependent histone H3K18 deacetylation in bacterial...
Published: August, 2013

Abstract: Pathogens dramatically affect host cell transcription programs for their own profit during infection, but in most cases, the underlying mechanisms ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

O-glycosylation as a novel control mechanism of peptidoglycan hydro...
Published: August, 2013

Abstract: Acm2, the major autolysin of Lactobacillus plantarum, is a tripartite protein. Its catalytic domain is surrounded by an O-glycosylated N-terminal r... Read more »

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Bioruptor

Genome-wide profiling identifies a subset of methamphetamine (METH)...
Published: August, 2013

Abstract: BACKGROUND: METH is an illicit drug of abuse that influences gene expression in the rat striatum. Histone modifications regulate gene transcription... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Binding of TFIIIC to SINE Elements Controls the Relocation of Activ...
Published: August, 2013

Abstract: In neurons, the timely and accurate expression of genes in response to synaptic activity relies on the interplay between epigenetic modifications o... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene...
Published: August, 2013

Abstract: The histone H2A variant H2A.Z is essential for embryonic development and for proper control of developmental gene expression programs in embryonic ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

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