Publications,References

Sox2 Expression Is Regulated by a Negative Feedback Loop in Embryon...
Published: October, 2013

Abstract: The self-renewal and pluripotency of embryonic stem cells (ESC) is regulated by a highly integrated network of essential transcription factors, whi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Combined modulation of polycomb and trithorax genes rejuvenates β c...
Published: October, 2013

Abstract: Inadequate functional β cell mass underlies both type 1 and type 2 diabetes. β Cell growth and regeneration also decrease with age through mechanis... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Spt6 regulates intragenic and antisense transcription, nucleosome p...
Published: October, 2013

Abstract: Spt6 is a highly conserved histone chaperone that interacts directly with both RNA polymerase II and histones to regulate gene expression. To gain ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Membrane-to-nucleus signaling links insulin-like growth factor-1- a...
Published: October, 2013

Abstract: STEM CELL FACTOR (MOUSE: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A Conserved Protein Motif Is Required for Full Modulatory Activity ...
Published: October, 2013

Abstract: NELF-B is a BRCA1-interacting protein and subunit (with NELF-A, -C/D, and -E) of the human negative elongation factor (NELF) complex, which partici... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Angiomodulin is required for cardiogenesis of embryonic stem cells ...
Published: October, 2013

Abstract: The transcription factor p63, member of the p53 gene family, encodes for two main isoforms, TAp63 and ΔNp63 with distinct functions on epithelial h... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Class I Lysine Deacetylases Facilitate Glucocorticoid-induced Trans...
Published: October, 2013

Abstract: Nuclear receptors use lysine acetyltransferases and lysine deacetylases (KDACs) in regulating transcription through histone acetylation. Lysine ace... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (...
Published: October, 2013

Abstract: Here we sought to identify transcription factors that induce ADAMTS5, a crucial proteinase for osteoarthritis development. Exhaustive comparison of... Read more »

PRMT5-mediated histone H4 arginine-3 symmetrical dimethylation mark...
Published: October, 2013

Abstract: Symmetrical dimethylation on arginine-3 of histone H4 (H4R3me2s) has been reported to occur at several repressed genes, but its specific regulation... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Epstein-Barr virus-mediated transformation of B cells induces globa...
Published: October, 2013

Abstract: Epstein-Barr virus (EBV) infects and transforms human primary B cells inducing indefinite proliferation. To investigate the potential participation... Read more »

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Antibody

Genomic organization of human transcription initiation complexes.
Published: October, 2013

Abstract: The human genome is pervasively transcribed, yet only a small fraction is coding. Here we address whether this non-coding transcription arises at p... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

A three-component signaling system finetunes expression kinetics of...
Published: October, 2013

Abstract: During adaptation to environments, bacteria employ two-component signal transduction systems, which contain histidine kinases and response regulato... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

ErbB2 upregulates the Na+,HCO3--cotransporter NBCn1/SLC4A7 in human...
Published: October, 2013

Abstract: Misregulation of acid-base transport plays central roles in cancer development. We previously demonstrated the strong up-regulation of the Na(+),HC... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Whole-exome sequencing supports genetic heterogeneity in childhood ...
Published: October, 2013

Abstract: The genetic basis of complex neurological disorders involving language are poorly understood, partly due to the multiple additive genetic risk fact... Read more »

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DNA shearing Bioruptor

DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation P...
Published: October, 2013

Abstract: During adipocyte differentiation, significant epigenomic changes occur in association with the implementation of the adipogenic program. We have pr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methy...
Published: October, 2013

Abstract: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant myopathy with a strong epigenetic component. It is associated with deletion ... Read more »

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Antibody

The APSES transcription factor Efg1 is a global regulator that cont...
Published: October, 2013

Abstract: Efg1 (a member of the APSES family) is an important regulator of hyphal growth and of the white-to-opaque transition in Candida albicans and very c... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Sumoylation at chromatin governs coordinated repression of a transc...
Published: October, 2013

Abstract: Despite numerous studies on specific sumoylated transcriptional regulators, the global role of SUMO on chromatin in relation to transcription regul... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Cell-Autonomous Regulation of Brown Fat Identity Gene UCP1 by Unlig...
Published: October, 2013

Abstract: White adipose tissue stores energy in the form of lipids, and brown adipose tissue expends energy via uncoupled fatty acid oxidation, which leads t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Dissection of the elements of osmotic stress response transcription...
Published: October, 2013

Abstract: The response to hyperosmotic stress is mediated by the HOG pathway. The MAP kinase Hog1 activates several transcription factors, regulates chromati... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Recombinant antibodies to histone post-translational modifications.
Published: October, 2013

Abstract: Variability in the quality of antibodies to histone post-translational modifications (PTMs) is a widely recognized hindrance in epigenetics researc... Read more »

Pregnenolone activates CLIP-170 to promote microtubule growth and c...
Published: October, 2013

Abstract: Pregnenolone (P5) is a neurosteroid that improves memory and neurological recovery. It is also required for zebrafish embryonic development. Howeve... Read more »

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Bioruptor

MEF2B mutations lead to deregulated expression of the oncogene BCL6...
Published: October, 2013

Abstract: MEF2B encodes a transcriptional activator and is mutated in ∼11% of diffuse large B cell lymphomas (DLBCLs) and ∼12% of follicular lymphomas (FLs).... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymet...
Published: October, 2013

Abstract: To uncover the function of and interplay between the mammalian cytosine modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), ne... Read more »

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DNA shearing Bioruptor

The trithorax group proteins Kismet and ASH1 promote H3K36 dimethyl...
Published: October, 2013

Abstract: Members of the Polycomb group of repressors and trithorax group of activators maintain heritable states of transcription by modifying nucleosomal h... Read more »

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Antibody

Early histone modifications in the ventromedial hypothalamus and pr...
Published: October, 2013

Abstract: Expression of the primary female sex behaviour, lordosis, in laboratory animals depends on oestrogen-induced expression of progesterone receptor (P... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Epigenetic memory at embryonic enhancers identified in DNA methylat...
Published: October, 2013

Abstract: Mammalian development requires cytosine methylation, a heritable epigenetic mark of cellular memory believed to maintain a cell's unique gene expre... Read more »

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DNA shearing Bioruptor

DNA methylation analysis of murine hematopoietic side population ce...
Published: October, 2013

Abstract: Stem cells have been found in most tissues/organs. These somatic stem cells produce replacements for lost and damaged cells, and it is not complete... Read more »

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IP-Star

Genome-wide shRNA screening to identify factors mediating Gata6 rep...
Published: October, 2013

Abstract: The use of whole-genome pooled shRNA libraries in loss-of-function screening in tissue culture models provides an effective means to identify novel... Read more »

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Antibody

Sequestration by IFIT1 impairs translation of 2'O-unmethylated capp...
Published: October, 2013

Abstract: Viruses that generate capped RNA lacking 2'O methylation on the first ribose are severely affected by the antiviral activity of Type I interferons.... Read more »

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Bioruptor Cell Lysis Mass Spectrometry

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