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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Identification of FOXM1-induced epigenetic markers for head and nec...
Published: October, 2013
Abstract: BACKGROUND Epigenetic reprogramming of the methylome has been implicated in all stages of cancer evolution. It is now well accepted that cancer ce... Read more »
Dynamic changes in DNA methylation and hydroxymethylation when hES ...
Published: October, 2013
Abstract: DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge is limited about the genom... Read more »
Transcription termination and chimeric RNA formation controlled by ...
Published: October, 2013
Abstract: Alternative cleavage and polyadenylation influence the coding and regulatory potential of mRNAs and where transcription termination occurs. Althoug... Read more »
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Antibody
tRNA methyltransferase homolog gene TRMT10A mutation in young onset...
Published: October, 2013
Abstract: We describe a new syndrome of young onset diabetes, short stature and microcephaly with intellectual disability in a large consanguineous family wi... Read more »
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Bioruptor Tissue Homogenization
Lamin A/C-promoter interactions specify chromatin state-dependent t...
Published: October, 2013
Abstract: The nuclear lamina is implicated in the organization of the eukaryotic nucleus. Association of nuclear lamins with the genome occurs through large ... Read more »
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Bioruptor Chromatin Shearing Antibody
Cap Completion and C-Terminal Repeat Domain Kinase Recruitment Unde...
Published: October, 2013
Abstract: After transcription initiation, RNA polymerase (Pol) II escapes from the promoter and recruits elongation factors. The molecular basis for the init... Read more »
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Bioruptor Chromatin Shearing
Genome-wide profiling reveals stimulus-specific functions of p53 du...
Published: September, 2013
Abstract: How tumor suppressor p53 selectively responds to specific signals, especially in normal cells, is poorly understood. We performed genome-wide profi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Tissue-specific differences in the regulation of KIBRA gene express...
Published: September, 2013
Abstract: KIBRA has been described as a key regulator of the Hippo signaling pathway, regulating organ size control, cell contact inhibition, cell growth, as... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gene regulation and priming by topoisomerase IIα in embryonic stem ...
Published: September, 2013
Abstract: Topoisomerases resolve torsional stress, while their function in gene regulation, especially during cellular differentiation, remains unknown. Here... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
TET2 is a Master Regulator of Smooth Muscle Cell Plasticity
Published: September, 2013
Abstract: Background—Smooth muscle cells (SMC) are remarkably plastic. Their reversible differentiation is required for growth and wound healing, but also co... Read more »
Human SNP Links Differential Outcomes in Inflammatory and Infectiou...
Published: September, 2013
Abstract: The clinical course and eventual outcome, or prognosis, of complex diseases varies enormously between affected individuals. This variability critic... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment...
Published: September, 2013
Abstract: Polycomb repressive complex 2 (PRC2) regulates gene expression during lineage specification through trimethylation of lysine 27 on histone H3 (H3K2... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Addiction of t(8;21) and inv(16) acute myeloid leukemia to native R...
Published: September, 2013
Abstract: The t(8;21) and inv(16) chromosomal aberrations generate the oncoproteins AML1-ETO (A-E) and CBFβ-SMMHC (C-S). The role of these oncoproteins in ac... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Insulin-activated Elk-1 recruits the TIP60/NuA4 complex to increase...
Published: September, 2013
Abstract: Insulin increases prolactin gene expression in GH4 cells through phosphorylation of Elk-1 (Jacob and Stanley, 2001). We preformed a reverse two-hyb... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dnmt3L antagonizes DNA methylation at bivalent promoters and favors...
Published: September, 2013
Abstract: The de novo DNA methyltransferase 3-like (Dnmt3L) is a catalytically inactive DNA methyltransferase that cooperates with Dnmt3a and Dnmt3b to methy... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Identification of an Enhancer That Increases miR-200b~200a~429 Gene...
Published: September, 2013
Abstract: The miR-200b~200a~429 gene cluster is a key regulator of EMT and cancer metastasis, however the transcription-based mechanisms controlling its expr... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The Reelin receptors ApoER2 and VLDLR are direct target genes of HI...
Published: September, 2013
Abstract: The tumor suppressor gene HIC1 (Hypermethylated In Cancer 1) is located in 17p13.3 a region frequently hypermethylated or deleted in tumors and in ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-Wide Analysis of DNA Methylation in Soybean.
Published: September, 2013
Abstract: Cytosine methylation is an important mechanism for dynamical regulation of gene expression. We identified 2162 differentially methylated regions in... Read more »
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DNA shearing Bioruptor
The BTB-Containing Protein Kctd15 Is SUMOylated In Vivo.
Published: September, 2013
Abstract: Potassium Channel Tetramerization Domain containing 15 (Kctd15) has a role in regulating the neural crest (NC) domain in the embryo. Kctd15 inhibit... Read more »
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DNA shearing Bioruptor Bioruptor Plus
Verification of Intraovum Transmission of a Microsporidium of Verte...
Published: September, 2013
Abstract: Direct transmission from parents to offspring, referred to as vertical transmission, occurs within essentially all major groups of pathogens. Sever... Read more »
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Bioruptor Cell Lysis
An integrated transcriptome and epigenome analysis identifies a nov...
Published: September, 2013
Abstract: Background Pancreatic cancer is a highly lethal cancer with limited diagnostic and therapeutic modalities. Methods To begin to explore the genom... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Human telomeres that carry an integrated copy of human herpesvirus ...
Published: September, 2013
Abstract: Linear chromosomes are stabilized by telomeres, but the presence of short dysfunctional telomeres triggers cellular senescence in human somatic tis... Read more »
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DNA shearing Bioruptor
SSR_pipeline: A Bioinformatic Infrastructure for Identifying Micros...
Published: September, 2013
Abstract: SSR_pipeline is a flexible set of programs designed to efficiently identify simple sequence repeats (e.g., microsatellites) from paired-end high-th... Read more »
Geminin Is Required for the Maintenance of Pluripotency
Published: September, 2013
Abstract: Pluripotency requires the expression of the three core transcriptions factors Oct4, Sox2 and Nanog, as well as further, complementary proteins. The... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Recent Diversification of a Marine Genus (Tursiops spp.) Tracks Hab...
Published: September, 2013
Abstract: Understanding the evolution of diversity and the resulting systematics in marine systems is confounded by the lack of clear boundaries in oceanic h... Read more »
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DNA shearing Bioruptor
Combinatorial functions of diverse histone methylations in Arabidop...
Published: September, 2013
Abstract: Previous studies in Arabidopsis thaliana have identified several histone methylation enzymes, including ARABIDOPSIS TRITHORAX1 (ATX1)/SET DOMAIN GR... Read more »
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Antibody
Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor P...
Published: September, 2013
Abstract: Following transcriptome comparison of primary cultures isolated from brain of mice expressing or not the amyloid precursor protein APP, we found tr... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
MiR-210 Is Induced by Oct-2, Regulates B Cells, and Inhibits Autoan...
Published: September, 2013
Abstract: MicroRNAs (MiRs) are small, noncoding RNAs that regulate gene expression posttranscriptionally. In this study, we show that MiR-210 is induced by O... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosin...
Published: September, 2013
Abstract: 5-Methylcytosine and methylated histones have been considered for a long time as stable epigenetic marks of chromatin involved in gene regulation. ... Read more »
The E7 oncoprotein from beta human papillomavirus type 38 induces t...
Published: September, 2013
Abstract: Our previous studies on cutaneous human papillomavirus (HPV) type 38 E6 and E7 oncoproteins highlighted a novel activity of IκB kinase beta (IKKβ) ... Read more »

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