Publications,References

Divergent antiviral effects of bioflavonoids on the hepatitis C vir...
Published: September, 2012

Abstract: We have previously demonstrated that quercetin, a bioflavonoid, blocks hepatitis C virus (HCV) proliferation by inhibiting NS5A-driven internal rib... Read more »

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Master Mix

Pesticide and Insect Repellent Mixture (Permethrin and DEET) Induce...
Published: September, 2012

Abstract: Environmental compounds are known to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine if a ... Read more »

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Antibody

Expression of MUC17 Is Regulated by HIF1α-Mediated Hypoxic Response...
Published: September, 2012

Abstract: MUC17 is a type 1 membrane-bound glycoprotein that is mainly expressed in the digestive tract. Recent studies have demonstrated that the aberrant o... Read more »

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Chromatin Shearing ChIP-qPCR

Argonaute proteins couple chromatin silencing to alternative splicing.
Published: September, 2012

Abstract: Argonaute proteins play a major part in transcriptional gene silencing in many organisms, but their role in the nucleus of somatic mammalian cells ... Read more »

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Bioruptor Chromatin Shearing

Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with...
Published: September, 2012

Abstract: Background Salinomycin is a polyether ionophore antibiotic that has recently been shown to induce cell death in human cancer cells displaying mult... Read more »

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Bioruptor Cell Lysis Western Blot

A mechanistic basis for amplification differences between samples a...
Published: September, 2012

Abstract: ABSTRACT: BACKGROUND: For many analytical methods the efficiency of DNA amplification varies across the genome and between samples. The most affect... Read more »

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DNA shearing Bioruptor

A Snapshot of Histone Modifications within Transposable Elements in...
Published: September, 2012

Abstract: Transposable elements (TEs) are a major source of genetic variability in genomes, creating genetic novelty and driving genome evolution. Analysis o... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Multigenerational epigenetic adaptation of the hepatic wound-healin...
Published: September, 2012

Abstract: We investigated whether ancestral liver damage leads to heritable reprogramming of hepatic wound healing in male rats. We found that a history of l... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K27me3 (C15410069)

Mutant p53 is a transcriptional co-factor that binds to G-rich regu...
Published: September, 2012

Abstract: The molecular mechanisms underlying mutant p53 (mutp53) “gain-of-function” (GOF) are still insufficiently understood, but there is evidence that mu... Read more »

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Bioruptor Chromatin Shearing

Genome-Wide Profiling of Peroxisome Proliferator-Activated Receptor...
Published: September, 2012

Abstract: Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipocyte differentiation and function. We and others have previously... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Widespread plasticity in CTCF occupancy linked to DNA methylation.
Published: September, 2012

Abstract: CTCF is a ubiquitously expressed regulator of fundamental genomic processes including transcription, intra- and interchromosomal interactions, and ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

BZLF1 Governs CpG-Methylated Chromatin of Epstein-Barr Virus Revers...
Published: September, 2012

Abstract: Epigenetic mechanisms are essential for the regulation of all genes in mammalian cells but transcriptional repression including DNA methylation are... Read more »

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DNA shearing Bioruptor

PARP activation regulates the RNA-binding protein NONO in the DNA d...
Published: August, 2012

Abstract: After the generation of DNA double-strand breaks (DSBs), poly(ADP-ribose) polymerase-1 (PARP-1) is one of the first proteins to be recruited and ac... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis

MutSβ and histone deacetylase complexes promote expansions of trinu...
Published: August, 2012

Abstract: Trinucleotide repeat (TNR) expansions cause at least 17 heritable neurological diseases, including Huntington's disease. Expansions are thought to ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammal...
Published: August, 2012

Abstract: Heterochromatin serves important functions, protecting genome integrity and stabilizing gene expression programs. Although the Suv39h methyltransfe... Read more »

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Bioruptor Cell Lysis

Serine 192 in the tiny RS repeat of the adenoviral L4-33K splicing ...
Published: August, 2012

Abstract: The adenovirus L4-33K protein is a key regulator involved in the temporal shift from early to late pattern of mRNA expression from the adenovirus m... Read more »

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Bioruptor Cell Lysis Western Blot Bioruptor Plus

INTRACRINE PROSTAGLANDIN E2 SIGNALLING REGULATES HYPOXIA-INDUCIBLE ...
Published: August, 2012

Abstract: We have previously found in human renal proximal tubular HK-2 cells that hypoxia- and all-trans retinoic acid-induced hypoxia-inducible factor-1 up... Read more »

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LowCell ChIP kit

Application of metatranscriptomics to soil environments
Published: August, 2012

Abstract: Read more »

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DNA shearing Bioruptor

Zinc finger transcription factor zDC is a negative regulator requir...
Published: August, 2012

Abstract: Classical dendritic cells (cDCs) process and present antigens to T cells. Under steady-state conditions, antigen presentation by cDCs induces toler... Read more »

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Bioruptor Chromatin Shearing Cell Lysis ChIP-seq Western Blot

Chromatin accessibility, p300 and histone acetylation define PML-RA...
Published: August, 2012

Abstract: Chromatin accessibility plays a key role in regulating cell type specific gene expression during hematopoiesis, but has also been suggested to be a... Read more »

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Antibody

Genomic Profiling of a Human Organotypic Model of AEC Syndrome Reve...
Published: August, 2012

Abstract: The basis for impaired differentiation in TP63 mutant ankyloblepharon-ectodermal dysplasia-clefting (AEC) syndrome is unknown. Human epidermis harb... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt b...
Published: August, 2012

Abstract: Interleukin-17A (IL-17A) is the signature cytokine produced by Th17 CD4(+) T cells and has been tightly linked to autoimmune pathogenesis. In parti... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus IPure kit

HOXB7 promotes invasion and predicts survival in pancreatic adenoca...
Published: August, 2012

Abstract: BACKGROUND: The homeobox gene HOXB7 is overexpressed across a range of cancers and promotes tumorigenesis through varying effects on proliferation... Read more »

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Master Mix

Genome-wide distribution of 5-formylcytosine in ES cells is associa...
Published: August, 2012

Abstract: ABSTRACT: BACKGROUND: Methylation of cytosine in DNA (5mC) is an important epigenetic mark that is involved in the regulation of genome function. D... Read more »

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DNA shearing Bioruptor

Use of allele-specific FAIRE to determine functional regulatory pol...
Published: August, 2012

Abstract: Following the widespread use of genome-wide association studies (GWAS), focus is turning towards identification of causal variants rather than simp... Read more »

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Bioruptor Chromatin Shearing

Candida albicans Infection Affords Protection against Reinfection v...
Published: August, 2012

Abstract: Immunological memory in vertebrates is often exclusively attributed to T and B cell function. Recently it was proposed that the enhanced and sustai... Read more »

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Antibody

The transcription factor Wilms tumor 1 confers resistance in myeloi...
Published: August, 2012

Abstract: TRAIL is considered a promising cancer therapeutic agent due to its ability to induce apoptosis in a variety of cancer cells, while sparing normal ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR HighCell ChIP kit

Histone acetylation and DNA demethylation of T-cells result in an a...
Published: August, 2012

Abstract: Background. A characteristic feature of anaplastic large cell lymphoma is the significant repression of the T-cell expression program despite its T... Read more »

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Antibody 5mC (C15200081)

Role of the HSP90-Associated Cochaperone p23 in Enhancing Activity ...
Published: August, 2012

Abstract: Prostate tumor growth initially depends on androgens, which act via the androgen receptor (AR). Despite androgen ablation therapy, tumors eventuall... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The Mammalian de novo DNA Methyltransferases Dnmt3a and Dnmt3b Are ...
Published: August, 2012

Abstract: For cytosine (C) demethylation of vertebrate DNA, it is known that the Tet proteins could convert 5-mC to 5-hydroxymethyl C (5-hmC). However, DNA d... Read more »

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