Publications,References

Up-regulation of 2-oxoglutarate dehydrogenase as a stress response.
Published: July, 2012

Abstract: 2-Oxoglutarate dehydrogenase multienzyme complex (OGDHC) operates at a metabolic cross-road, mediating Ca(2+)- and ADP-dependent signals in mitocho... Read more »

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Bioruptor Cell Lysis

Chromatin measurements reveal contributions of synthesis and decay ...
Published: July, 2012

Abstract: Messenger RNA levels in eukaryotes are controlled by multiple consecutive regulatory processes, which can be classified into two layers: primary tr... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

A comparison of transcriptome and epigenetic status between closely...
Published: July, 2012

Abstract: Difference in the level of expression of genes is one of the factors contributing to plant phenotype. As well as being under genetic control, gene ... Read more »

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Antibody

An epigenetic silencing pathway controlling T helper 2 cell lineage...
Published: July, 2012

Abstract: During immune responses, naive CD4+ T cells differentiate into several T helper (TH) cell subsets under the control of lineage-specifying genes. Th... Read more »

Supp. mat - An epigenetic silencing pathway controlling T helper 2 ...
Published: July, 2012

Abstract: During immune responses, naive CD4+ T cells differentiate into several T helper (TH) cell subsets under the control of lineage-specifying genes. Th... Read more »

Dynamic Changes in Ezh2 Gene Occupancy Underlie Its Involvement in ...
Published: July, 2012

Abstract: Background: The polycomb group protein Ezh2 is an epigenetic repressor of transcription originally found to prevent untimely differentiation of plu... Read more »

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Antibody

A Key Role for Chd1 in Histone H3 Dynamics at the 3′ Ends of Long G...
Published: July, 2012

Abstract: Chd proteins are ATP–dependent chromatin remodeling enzymes implicated in biological functions from transcriptional elongation to control of plurip... Read more »

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Bioruptor Chromatin Shearing

Genome-wide Analysis Reveals Extensive Functional Interaction betwe...
Published: July, 2012

Abstract: Identification of replication initiation sites, termed origins, is a crucial step in understanding genome transmission in any organism. Transcripti... Read more »

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Bioruptor Chromatin Shearing

An essential novel component of the non-canonical mitochondrial out...
Published: July, 2012

Abstract: The mitochondrial outer membrane protein Tom40 is the general entry gate for imported proteins in essentially all eukaryotes. Trypanosomatids howev... Read more »

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Antibody

Ecdysone Induced Gene Expression Is Associated with Acetylation of ...
Published: July, 2012

Abstract: Posttranslational modification of histones regulates transcription but the exact role that acetylation of specific lysine residues plays in biologi... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Glucocorticoids Modulate the mTOR Pathway in the Hippocampus: Diffe...
Published: July, 2012

Abstract: Glucocorticoid (GC) hormones, released by the adrenals in response to stress, are key regulators of neuronal plasticity. In the brain, the hippocam... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The transcription factor Lyl-1 regulates lymphoid specification and...
Published: July, 2012

Abstract: Thymopoiesis depends on the recruitment and expansion of bone marrow-derived progenitor populations; tight regulation of these processes is require... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR ChIP-seq

SATB1-mediated Functional Packaging of Chromatin into Loops.
Published: July, 2012

Abstract: Mammalian genomes are organized into multiple layers of higher-order chromatin structure, and in this organization chromatin looping is a striking ... Read more »

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DNA shearing Bioruptor Chromatin Shearing

An investigation of the affinities, specificity and kinetics involv...
Published: July, 2012

Abstract: Human transcription factor Yin Yang 1 (YY1) is a four-zinc-finger protein that regulates a large number of genes with different biological function... Read more »

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DNA shearing Bioruptor

Histone H2B monoubiquitination is required to reach maximal transcr...
Published: July, 2012

Abstract: Previously, we had identified HISTONE MONOUBIQUITINATION1 (HUB1) as an unconventional ubiquitin E3 ligase that was not involved in protein degradat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Lipocalin 2 (LCN2), the TNF-like receptor TWEAKR and its ligand TWE...
Published: July, 2012

Abstract: NFAT1 is a transcription factor that elicits breast carcinoma cells to become invasive, contributing thus to formation of metastasis. The molecular... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The human CST complex is a terminator of telomerase activity.
Published: July, 2012

Abstract: The lengths of human telomeres, which protect chromosome ends from degradation and end fusions, are crucial determinants of cell lifespan. During e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Aberrant expression of IFN-γ in Th2 cells from Th2 LCR-deficient mice.
Published: July, 2012

Abstract: The Th2 locus control region (LCR) has been shown to be a crucial cis-acting element for Th2 cytokine expression and Th2 cell differentiation. To s... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

XPG and XPF Endonucleases Trigger Chromatin Looping and DNA Demethy...
Published: July, 2012

Abstract: Nucleotide excision repair factors, initially characterized as part of DNA repair, have been shown to participate in the transcriptional process in... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Occludin is a direct target of thyroid transcription factor-1 (TTF-...
Published: July, 2012

Abstract: The thyroid transcription factor 1 gene (TTF-1 or NKX2-1) is essential to lung development; however, it is also a critical factor in lung cancer. T... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide characterization of Foxa2 targets reveals upregulation ...
Published: July, 2012

Abstract: The transcription factors Foxa1 and Foxa2 promote the specification of midbrain dopaminergic (mDA) neurons and the floor plate. Whether their role ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) d...
Published: July, 2012

Abstract: The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Transcription termination between polo and snap, two closely spaced...
Published: July, 2012

Abstract: Transcription termination of RNA polymerase II between closely spaced genes is an important, though poorly understood, mechanism. This is true, in ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Live cell monitoring of periodic gene expression in synchronous hum...
Published: June, 2012

Abstract: We developed a system to monitor periodic luciferase activity from cell cycle-regulated promoters in synchronous cells. Reporters were driven by a ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Cohesins Repress KSHV Immediate Early Gene Transcription During Lat...
Published: June, 2012

Abstract: Chromatin-organizing factors, like CTCF and cohesins, have been implicated in the control of complex viral regulatory programs. We investigated the... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Neurog2 Simultaneously Activates and Represses Alternative Gene Exp...
Published: June, 2012

Abstract: Progenitor cells undergo a series of stable identity transitions on their way to becoming fully differentiated cells with unique identities. Each c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Cdc28 kinase activity regulates the basal transcription machinery a...
Published: June, 2012

Abstract: The cyclin-dependent kinase Cdc28 is the master regulator of the cell cycle in Saccharomyces cerevisiae. Cdc28 initiates the cell cycle by activati... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Separating the wheat from the chaff: mitigating the effects of nois...
Published: June, 2012

Abstract: ABSTRACT: BACKGROUND: Through next-generation sequencing, the amount of sequence data potentially available for phylogenetic analyses has increased... Read more »

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DNA shearing Bioruptor

ZRF1 controls oncogene-induced senescence through the INK4-ARF locus.
Published: June, 2012

Abstract: The reactivation of the INK4-ARF locus, which is epigenetically repressed by Polycomb proteins in healthy cells, is a hallmark of senescence. One m... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Fluorescence-based phenotypic selection allows forward genetic scre...
Published: June, 2012

Abstract: The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in app... Read more »

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DNA shearing Bioruptor

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