Publications,References

ZRF1 controls oncogene-induced senescence through the INK4-ARF locus.
Published: June, 2012

Abstract: The reactivation of the INK4-ARF locus, which is epigenetically repressed by Polycomb proteins in healthy cells, is a hallmark of senescence. One m... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Fluorescence-based phenotypic selection allows forward genetic scre...
Published: June, 2012

Abstract: The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in app... Read more »

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DNA shearing Bioruptor

Histone demethylase Kdm4b functions as a co-factor of C/EBPβ to pro...
Published: June, 2012

Abstract: CCAAT/enhancer-binding protein (C/EBP) β is required for both mitotic clonal expansion (MCE) and terminal adipocyte differentiation of 3T3-L1 pread... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Dynamic hydroxymethylation of deoxyribonucleic acid marks different...
Published: June, 2012

Abstract: Enhancers are developmentally controlled transcriptional regulatory regions whose activities are modulated through histone modifications or histone... Read more »

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Antibody

Genome-wide profiling in melatonin exposed human breast cancer cell...
Published: June, 2012

Abstract: Epigenetic alterations have emerged as an important mechanism involved in tumorigenesis. The epigenetic impact of DNA methylation in various types ... Read more »

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MeDIP kit

The Saccharomyces cerevisiae Hot1p regulated gene YHR087W (HGI1) ha...
Published: June, 2012

Abstract: ABSTRACT: BACKGROUND: While growing in natural environments yeasts can be affected by osmotic stress provoked by high glucose concentrations. The r... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Bovine polledness - an autosomal dominant trait with allelic hetero...
Published: June, 2012

Abstract: The persistent horns are an important trait of speciation for the family Bovidae with complex morphogenesis taking place briefly after birth. The p... Read more »

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DNA shearing Bioruptor

Topoisomerase II is required for the production of long Pol II gene...
Published: June, 2012

Abstract: The extent to which the DNA relaxation activities of eukaryotic topoisomerases (topo I and topo II) are redundant during gene transcription is uncl... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A Cell Cycle Role for the Epigenetic Factor CTCF-L/BORIS.
Published: June, 2012

Abstract: CTCF is a ubiquitous epigenetic regulator that has been proposed as a master keeper of chromatin organisation. CTCF-like, or BORIS, is thought to a... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF...
Published: June, 2012

Abstract: The CACCC-box binding protein Erythroid Krüppel-like Factor (EKLF/KLF1) is a master regulator that directs the expression of many important erythro... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit

Extensive promoter hypermethylation and hypomethylation is associat...
Published: June, 2012

Abstract: Dysregulated microRNA (miRNA) expression contributes to the pathogenesis of hematopoietic malignancies, including chronic lymphocytic leukemia (CLL... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star Antibody H3K4me3 (C15410003) Bioruptor Plus

Defective mitochondrial morphology and bioenergetic function in mic...
Published: June, 2012

Abstract: Formation, distribution and maintenance of functional mitochondria are achieved through dynamic processes that strictly depend on transcription of ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Targeted re-sequencing of the allohexaploid wheat exome.
Published: June, 2012

Abstract: Bread wheat, Triticum aestivum, is an allohexaploid composed of the three distinct ancestral genomes, A, B and D. The polyploid nature of the wheat... Read more »

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DNA shearing Bioruptor

GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chro...
Published: June, 2012

Abstract: JunB, an activator protein-1 (AP-1) transcription factor component, acts either as a tumor suppressor or as an oncogene depending on the cell conte... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Rsx is a metatherian RNA with Xist-like properties in X-chromosome ...
Published: June, 2012

Abstract: In female (XX) mammals, one of the two X chromosomes is inactivated to ensure an equal dose of X-linked genes with males (XY). X-chromosome inactiv... Read more »

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DNA shearing Bioruptor

PGC-1β regulates mouse carnitine-acylcarnitine translocase through ...
Published: June, 2012

Abstract: Carnitine/acylcarnitine translocase (CACT) is a mitochondrial-membrane carrier proteins that mediates the transport of acylcarnitines into the mito... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Identification of PR-SET7 and EZH2 selective inhibitors inducing ce...
Published: June, 2012

Abstract: Chemical manipulations undertaken on some bis(bromo- and dibromo-phenol) compounds previously reported by us as wide-spectrum epigenetic inhibitors... Read more »

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Antibody

Phosphorylated and small ubiquitin-like modifier protein-deficient ...
Published: June, 2012

Abstract: ABSTRACT: INTRODUCTION: Progesterone receptors (PR) are emerging as important breast cancer drivers. Phosphorylation events common to breast cancer... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leuko...
Published: June, 2012

Abstract: Locally acting insulin growth factor isoform (mIGF-1) and the NAD+-dependent protein deacetylase SIRT1 are implicated in life and health span. Hear... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Functional characterization of the promoter region of the human EVI...
Published: June, 2012

Abstract: The EVI1 gene (3q26) codes for a transcription factor with important roles in normal hematopoiesis and leukemogenesis. High expression of EVI1 is a... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Whole-Exome Sequencing and High Throughput Genotyping Identified KC...
Published: June, 2012

Abstract: BACKGROUND: Maturity-onset of the young (MODY) is a clinically heterogeneous form of diabetes characterized by an autosomal-dominant mode of inheri... Read more »

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DNA shearing Bioruptor

RNA Polymerase II Pausing Downstream of Core Histone Genes Is Diffe...
Published: June, 2012

Abstract: Recent genome-wide chromatin immunoprecipitation coupled high throughput sequencing (ChIP-seq) analyses performed in various eukaryotic organisms, ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Genome-Wide DNA Methylation Changes between the Superficial and Dee...
Published: June, 2012

Abstract: Read more »

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DNA shearing Bioruptor Antibody

Phosphorylation of p65(RelA) on Ser547 by ATM Represses NF-κB-Depen...
Published: June, 2012

Abstract: Read more »

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Antibody

The histone H2B monoubiquitination regulatory pathway is required f...
Published: June, 2012

Abstract: Extensive changes in posttranslational histone modifications accompany the rewiring of the transcriptional program during stem cell differentiation... Read more »

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Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)

Genome-wide localization and expression profiling establish Sp2 as ...
Published: June, 2012

Abstract: The transcription factor Sp2 is essential for early mouse development and for proliferation of mouse embryonic fibroblasts in culture. Yet its mech... Read more »

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Antibody

Recruitment of histone deacetylase 3 to the interferon-a gene promo...
Published: June, 2012

Abstract: BACKGROUND: Induction of Type I Interferon (IFN) genes constitutes an essential step leading to innate immune responses during virus infection. Sen... Read more »

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Antibody

Transcriptional networks driving enhancer function in the CFTR gene.
Published: June, 2012

Abstract: A critical cis-regulatory element for the cystic fibrosis transmembrane conductance regulator (CFTR) gene is located in intron 11, 100 kb distal to... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

GSK3 Temporally Regulates Neurogenin 2 Proneural Activity in the Ne...
Published: June, 2012

Abstract: The neocortex is comprised of six neuronal layers that are generated in a defined temporal sequence. While extrinsic and intrinsic cues are known t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Developmentally non-redundant SET domain proteins SUVH2 and SUVH9 a...
Published: June, 2012

Abstract: In plants, RNA-directed DNA methylation (RdDM) and related transcriptional gene silencing (TGS) involve members of the suppressor of variegation 3-... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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