Publications,References

Genomics of DNA cytosine methylation in Escherichia coli reveals it...
Published: June, 2012

Abstract: DNA cytosine methylation regulates gene expression in mammals. In bacteria, its role in gene expression and genome architecture is less understood.... Read more »

Tags
DNA shearing Bioruptor

Intronic RNAs mediate EZH2 regulation of epigenetic targets.
Published: June, 2012

Abstract: Epigenetic deregulation at a number of genomic loci is one of the hallmarks of cancer. A role for some RNA molecules in guiding repressive polycomb... Read more »

Tags
Antibody LowCell ChIP kit H3K4me3 (C15410003) H3K27me3 (C15410069)

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to ...
Published: June, 2012

Abstract: Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response...
Published: June, 2012

Abstract: Here we demonstrate that RNF4, a highly conserved small ubiquitin-like modifier (SUMO)-targeted ubiquitin E3 ligase, plays a critical role in the r... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

FOXO1 in the ventromedial hypothalamus regulates energy balance.
Published: June, 2012

Abstract: The transcription factor FOXO1 plays a central role in metabolic homeostasis by regulating leptin and insulin activity in many cell types, includin... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Histone H2B Ubiquitylation Promotes Activity of the Intact Set1 His...
Published: June, 2012

Abstract: The methylation of histone H3 at lysine 4 (H3K4me) is critical for the formation of transcriptionally active chromatin in eukaryotes. In yeast, Dro... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Genome structure-based screening identified epigenetically silenced...
Published: June, 2012

Abstract: MicroRNA (miRNA) expression is frequently altered in human cancers. To search for epigenetically silenced miRNAs in non-small-cell lung cancer (NSC... Read more »

Preferential Genome Targeting of the CBP Co-Activator by Rel and Sm...
Published: June, 2012

Abstract: CBP and the related p300 protein are widely used transcriptional co-activators in metazoans that interact with multiple transcription factors. Whet... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Overexpression of HGF attenuates the degeneration of Purkinje cells...
Published: June, 2012

Abstract: Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant disorder associated with cerebellar neurodegeneration caused by expansion of a CAG re... Read more »

Tags
Tissue Homogenization

Multiple Histone Methyl and Acetyltransferase Complex Components Bi...
Published: May, 2012

Abstract: Major histocompatibility complex class II (MHC-II) genes are fundamental components that contribute to adaptive immune responses. While characteriz... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Serum Response Factor and cAMP Response Element Binding Protein Are...
Published: May, 2012

Abstract: The molecular mechanism underlying induction by cocaine of ΔFosB, a transcription factor important for addiction, remains unknown. Here, we demonst... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Disruptive cell cycle regulation involving epigenetic downregulatio...
Published: May, 2012

Abstract: Cell cycle aberration was immunohistochemically examined in relation to preneoplastic liver cell foci expressing glutathione S-transferase placenta... Read more »

Tags
DNA shearing MeDIP kit

Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a S...
Published: May, 2012

Abstract: Inactivating mutations in the MEN1 gene predisposing to the multiple endocrine neoplasia type 1 (MEN1) syndrome can also cause sporadic pancreatic ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

Myb-binding protein 1a (Mybbp1a) regulates levels and processing of...
Published: May, 2012

Abstract: Ribosomal RNA gene transcription, co-transcriptional processing and ribosome biogenesis are highly coordinated processes that are tightly regulated... Read more »

Tags
Bioruptor

Mus81-Mms4 function as a single heterodimer to cleave nicked interm...
Published: May, 2012

Abstract: The formation of crossovers is a fundamental genetic process. The XPF-family endonuclease, Mus81-Mms4 (Eme1), contributes significantly to crossing... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

The aryl hydrocarbon receptor ligands 2,3,7,8-tetrachlorodibenzo-p-...
Published: May, 2012

Abstract: The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (ED... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide ...
Published: May, 2012

Abstract: Epigenetic regulation is an essential process for the normal functioning of genes. Therefore, targeting epigenetic dysregulation in cancer may be a... Read more »

Tags
Antibody

Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDA...
Published: May, 2012

Abstract: Read more »

Tags
Antibody

Epigenetic Repression of RARRES1 Is Mediated by Methylation of a Pr...
Published: May, 2012

Abstract: BACKGROUND: The cis-acting promoter element responsible for epigenetic silencing of retinoic acid receptor responder 1 (RARRES1) by methylation is ... Read more »

Tags
Antibody

Functional Genomic Methods to Study Estrogen Receptor Activity.
Published: May, 2012

Abstract: Estrogen Receptor (ER) is a nuclear receptor that mediates the actions of estrogen and tamoxifen. ER is expressed in a major fraction of human brea... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq Antibody

Dynamics of enhancer chromatin signatures mark the transition from ...
Published: May, 2012

Abstract: The generation of distinctive cell types that form different tissues and organs requires precise, temporal and spatial control of gene expression. ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq Antibody

Evolution of Burkholderia pseudomallei in Recurrent Melioidosis.
Published: May, 2012

Abstract: Burkholderia pseudomallei, the etiologic agent of human melioidosis, is capable of causing severe acute infection with overwhelming septicemia lead... Read more »

Tags
DNA shearing Bioruptor

The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulate...
Published: May, 2012

Abstract: Lineage commitment studies in mammary glands have focused on identifying cell populations that display stem or progenitor properties. However, the ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

The angiogenesis suppressor gene AKAP12 is under the epigenetic con...
Published: May, 2012

Abstract: Histone deacetylases (HDACs) are a family of 18 enzymes that deacetylate lysine residues of both histone and nonhistone proteins and to a large ext... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit

HIF1A induces expression of the WASF3 metastasis-associated gene un...
Published: May, 2012

Abstract: The WASF3 (WAVE3) gene is an important mediator of cell motility, invasion and metastasis and is expressed at high levels in some advanced stage tu... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

The linker histone plays a dual role during gametogenesis in S. cer...
Published: May, 2012

Abstract: The differentiation of gametes involves dramatic changes to chromatin, affecting transcription, meiosis, and cell morphology. Sporulation in S. cer... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis ChIP-seq Western Blot

BIM promoter directly targeted by EBNA3C in polycomb-mediated repre...
Published: May, 2012

Abstract: Detailed analyses of the chromatin around the BIM promoter has revealed that latent Epstein-Barr virus (EBV) triggers the recruitment of polycomb r... Read more »

Tags
DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR

Glucose-Dependent Regulation of NR2F2 Promoter and Influence of SNP...
Published: May, 2012

Abstract: BACKGROUND: The Nuclear Receptor 2F2 (NR2F2/COUP-TFII) heterozygous knockout mice display low basal insulinemia and enhanced insulin sensitivity. W... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Integrative genomics identifies the corepressor SMRT as a gatekeepe...
Published: May, 2012

Abstract: The molecular role of corepressors is poorly understood. Here, we studied the transcriptional function of the corepressor SMRT during terminal adip... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq

A Long ncRNA Links Copy Number Variation to a Polycomb/Trithorax Ep...
Published: May, 2012

Abstract: Repetitive sequences account for more than 50% of the human genome. Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Publications

活动