Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates...
Published: March, 2012

Abstract: The generation of induced pluripotent stem cells (iPSCs) often results in aberrant epigenetic silencing of the imprinted Dlk1-Dio3 gene cluster, co... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Mutually exclusive binding of telomerase RNA and DNA by ku alters t...
Published: March, 2012

Abstract: In Saccharomyces cerevisiae, the Ku heterodimer contributes to telomere maintenance as a component of telomeric chromatin and as an accessory subun... Read more »

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Bioruptor Cell Lysis
Mapping and Functional Characterisation of a CTCF-Dependent Insulat...
Published: March, 2012

Abstract: The Scl gene encodes a transcription factor essential for haematopoietic development. Scl transcription is regulated by a panel of cis-elements spr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
RYBP Represses Endogenous Retroviruses and Preimplantation- and Ger...
Published: March, 2012

Abstract: Polycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function. RYBP binds Polycomb H2A monoubiquitin... Read more »

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Bioruptor Chromatin Shearing
Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating...
Published: March, 2012

Abstract: The Mixl1 homeodomain protein plays a key role in mesendoderm patterning during embryogenesis, but its target genes remain to be identified. We com... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The rs3743205 SNP Is Important for the Regulation of the Dyslexia C...
Published: March, 2012

Abstract: Estrogen is involved in numerous physiological processes such as growth, differentiation, and function of the male and female reproductive tissues.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
EZH2 couples pancreatic regeneration to neoplastic progression.
Published: March, 2012

Abstract: Although the polycomb group protein Enhancer of Zeste Homolog 2 (EZH2) is well recognized for its role as a key regulator of cell differentiation, ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Widespread site-dependent buffering of human regulatory polymorphism.
Published: March, 2012

Abstract: The average individual is expected to harbor thousands of variants within non-coding genomic regions involved in gene regulation. However, it is cu... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Small-molecule-induced DNA damage identifies alternative DNA struct...
Published: March, 2012

Abstract: Guanine-rich DNA sequences that can adopt non-Watson-Crick structures in vitro are prevalent in the human genome. Whether such structures normally ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal t...
Published: March, 2012

Abstract: Pancreas development is initiated by the specification and expansion of a small group of endodermal cells. Several transcription factors are crucia... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the ...
Published: March, 2012

Abstract: To elucidate the molecular mechanism underlying the endochondral ossification process during the skeletal growth and osteoarthritis (OA) developmen... Read more »

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Antibody
Dynamic MicroRNA Gene Transcription and Processing during T Cell De...
Published: February, 2012

Abstract: By disrupting microRNA (miRNA) biogenesis, we previously showed that this pathway is critical for the differentiation and function of T cells. Alth... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Transcriptional induction of salt-inducible kinase 1 by transformin...
Published: February, 2012

Abstract: Transforming growth factor β (TGFβ)1 regulates many physiological processes and requires control mechanisms to safeguard proper and timely action. ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin structural changes around satellite repeats on the female...
Published: February, 2012

Abstract: BACKGROUND: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heteroga... Read more »

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Antibody H3K27me3 (C15410069)
Prenatal detection of aneuploidy and imbalanced chromosomal arrange...
Published: February, 2012

Abstract: Fetal chromosomal abnormalities are the most common reasons for invasive prenatal testing. Currently, G-band karyotyping and several molecular gene... Read more »

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DNA shearing Bioruptor
Transgenerational actions of environmental compounds on reproductiv...
Published: February, 2012

Abstract: Environmental factors during fetal development can induce a permanent epigenetic change in the germ line (sperm) that then transmits epigenetic tra... Read more »

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Antibody
Human Histone Acetyltransferase 1 Protein Preferentially Acetylates...
Published: February, 2012

Abstract: In mammalian cells, canonical histone H3 (H3.1) and H3 variant (H3.3) differ by five amino acids and are assembled, along with histone H4, into nuc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional Activation of the Adenoviral Genome Is Mediated by ...
Published: February, 2012

Abstract: Gene expression of DNA viruses requires nuclear import of the viral genome. Human Adenoviruses (Ads), like most DNA viruses, encode factors within ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
3T3 Cell Lines Stably Expressing Pax6 or Pax6(5a) – A New Tool Used...
Published: February, 2012

Abstract: Pax6 and Pax6(5a) are two isoforms of the evolutionary conserved Pax6 gene often co-expressed in specific stochiometric relationship in the brain a... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein ...
Published: February, 2012

Abstract: Myelination by oligodendrocytes in the central nervous system (CNS) is essential for proper brain function, yet the molecular determinants that con... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Circadian rhythms govern cardiac repolarization and arrhythmogenesis
Published: February, 2012

Abstract: Sudden cardiac death exhibits diurnal variation in both acquired and hereditary forms of heart disease1,2, but the molecular basis of this variatio... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Polycomb repressive complex 2-dependent and -independent functions ...
Published: February, 2012

Abstract: Jarid2 was recently identified as an important component of the mammalian Polycomb Repressive Complex 2 (PRC2), where it has a major effect on PRC2... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Ade...
Published: February, 2012

Abstract: Accumulation of the complex set of alternatively processed mRNA from the adenovirus major late transcription unit (MLTU) is subjected to a temporal... Read more »

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Bioruptor Cell Lysis
Kinetics of DNA methylation inheritance by the Dnmt1-including comp...
Published: February, 2012

Abstract: ABSTRACT: BACKGROUND: The clonal transmission of lineage-specific DNA methylation patterns in a mammalian genome during the cellular division is a ... Read more »

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DNA shearing Bioruptor
The Receptor Tyrosine Kinase EphA2 Is a Direct Target Gene of Hyper...
Published: February, 2012

Abstract: The tumor suppressor gene hypermethylated in cancer 1 (HIC1), which encodes a transcriptional repressor, is epigenetically silenced in many human t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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