Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Frequent aberrant expression of the human ether à go-go (hEAG1) pot...
Published: March, 2012

Abstract: Compelling evidence indicates that the human ether-à-go-go voltage-gated potassium channels (hEAG1) may represent new valuable membrane therapeutic... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signa...
Published: March, 2012

Abstract: Aberrant ErbB2 receptor tyrosine kinase activation in breast cancer is strongly linked to an invasive disease. The molecular basis of ErbB2-driven ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
A synthetic biology approach to self-regulatory recombinant protein...
Published: March, 2012

Abstract: ABSTRACT: BACKGROUND: Recombinant protein production is a process of great industrial interest, with products that range from pharmaceuticals to bi... Read more »

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Bioruptor Cell Lysis Western Blot
hnRNP C tetramer measures RNA length to classify RNA polymerase II ...
Published: March, 2012

Abstract: Specific RNA recognition is usually achieved by specific RNA sequences and/or structures. However, we show here a mechanism by which RNA polymerase... Read more »
Sequential ChIP-bisulfite sequencing enables direct genome-scale in...
Published: March, 2012

Abstract: Cross-talk between DNA methylation and histone modifications drives the establishment of composite epigenetic signatures and is traditionally studi... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody
The lhx2 transcription factor controls thalamocortical axonal guida...
Published: March, 2012

Abstract: The assembly of neural circuits is dependent upon the generation of specific neuronal subtypes, each subtype displaying unique properties that dire... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Inflammasome-Activated Caspase 7 Cleaves PARP1 to Enhance the Expre...
Published: March, 2012

Abstract: Caspase 1 is part of the inflammasome, which is assembled upon pathogen recognition, while caspases 3 and/or 7 are mediators of apoptotic and nonap... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The Histone Demethylase KDM1A Sustains the Oncogenic Potential of M...
Published: March, 2012

Abstract: Using a mouse model of human MLL-AF9 leukemia, we identified the lysine-specific demethylase KDM1A (LSD1 or AOF2) as an essential regulator of leuk... Read more »
DNA methylation dynamics, metabolic fluxes, gene splicing, and alte...
Published: March, 2012

Abstract: In honey bees (Apis mellifera), the development of a larva into either a queen or worker depends on differential feeding with royal jelly and invol... Read more »

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DNA shearing Bioruptor
Analysis of Chromatin Dynamics during Glucocorticoid Receptor Activ...
Published: March, 2012

Abstract: Steroid hormone receptors initiate a genetic program tightly regulated by the chromatin environment of the responsive regions. Using the glucocorti... Read more »

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Bioruptor Chromatin Shearing
A dual Role for the dREAM/MMB complex in the regulation of differen...
Published: March, 2012

Abstract: E2F and RB proteins regulate the expression of genes involved in cell cycle progression, apoptosis, differentiation, and development. Recent studie... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
DBIRD complex integrates alternative mRNA splicing with RNA polymer...
Published: March, 2012

Abstract: Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Spli... Read more »

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Bioruptor RNA Shearing
Low-Dose Cd Induces Hepatic Gene Hypermethylation, along with the P...
Published: March, 2012

Abstract: BACKGROUND: Cadmium (Cd) is classified as a human carcinogen probably associated with epigenetic changes. DNA methylation is one of epigenetic mech... Read more »

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DNA shearing Bioruptor
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights...
Published: March, 2012

Abstract: Synovial sarcoma is a translocation-associated sarcoma where the underlying chromosomal event generates SS18-SSX fusion transcripts. In vitro and i... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis.
Published: March, 2012

Abstract: The regulatory networks of differentiation programs have been partly characterized; however, the molecular mechanisms of lineage-specific gene regu... Read more »

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DNA shearing Bioruptor
Mammalian HCA66 protein is required for both ribosome synthesis and...
Published: March, 2012

Abstract: Ribosome production, one of the most energy-consuming biosynthetic activities in living cells, is adjusted to growth conditions and coordinated wit... Read more »

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Bioruptor Cell Lysis Western Blot
Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidops...
Published: March, 2012

Abstract: Nucleosomes package eukaryotic DNA and are composed of four different histone proteins, designated H3, H4, H2A, and H2B. Histone H3 has two main va... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
DLK2 is a transcriptional target of KLF4 in the early stages of adi...
Published: March, 2012

Abstract: The epidermal growth factor-like protein DLK2, highly homologous to DLK1, has been identified as a modulator of adipogenesis in vitro. Knocking dow... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
An epigenetic mechanism for high, synergistic expression of indolea...
Published: March, 2012

Abstract: IDO1 can be induced by interferon gamma (IFN-γ) in multiple cell types. We have earlier described that the DNA methyltransferase inhibitor zebulari... Read more »
Proteome analysis of Acetobacter pasteurianus during acetic acid fe...
Published: March, 2012

Abstract: Acetic acid bacteria (AAB) are Gram-negative, strictly aerobic microorganisms that show a unique resistance to ethanol (EtOH) and acetic acid (AcH)... Read more »

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Bioruptor Cell Lysis
Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with...
Published: March, 2012

Abstract: Mutations of the Wnt5a gene, encoding a ligand of the non-canonical Wnt pathway, and the Ror2 gene, encoding its receptor, have been found in patie... Read more »

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LowCell ChIP kit
Identification and characterization of ToRC, a novel ISWI-containin...
Published: March, 2012

Abstract: SNF2-like motor proteins, such as ISWI, cooperate with histone chaperones in the assembly and remodeling of chromatin. Here we describe a novel, ev... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide evaluation of histone methylation changes associated wi...
Published: March, 2012

Abstract: Leaf senescence is the orderly dismantling of older tissue that allows recycling of nutrients to developing portions of the plant and is accompanie... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Resveratrol Inhibits KSHV Reactivation by Lowering the Levels of Ce...
Published: March, 2012

Abstract: In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Toxoplasma gondii Chromodomain Protein 1 Binds to Heterochromatin a...
Published: March, 2012

Abstract: Background Apicomplexan parasites are responsible for some of the most deadly parasitic diseases afflicting humans, including malaria and toxoplas... Read more »
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites...
Published: March, 2012

Abstract: Polycomb group (PcG) proteins are involved in epigenetic silencing where they function as major determinants of cell identity, stem cell pluripoten... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Methylome analysis using MeDIP-seq with low DNA concentrations.
Published: March, 2012

Abstract: DNA methylation is an epigenetic mark that has a crucial role in many biological processes. To understand the functional consequences of DNA methyl... Read more »

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DNA shearing Bioruptor IP-Star MagMeDIP kit
Integrated epigenome profiling of repressive histone modifications,...
Published: March, 2012

Abstract: Epigenetic regulation of gene expression is commonly altered in human cancer. We have observed alterations of DNA methylation and microRNA expressi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Estrogen receptor alpha mediates progestin-induced mammary tumor gr...
Published: March, 2012

Abstract: Synthetic progesterone used in contraception drugs (progestins) can promote breast cancer growth but the mechanisms involved are unknown. Moreover,... Read more »

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HighCell ChIP kit
Chromatin-modifying enzymes as modulators of reprogramming.
Published: March, 2012

Abstract: Generation of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming involves global epigenetic remodelling. Whereas several proteins... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

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