Publications,References

Ultrasensitive proteome analysis using paramagnetic bead technology.
Published: October, 2014

Abstract: In order to obtain a systems-level understanding of a complex biological system, detailed proteome information is essential. Despite great progress... Read more »

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Bioruptor Cell Lysis

Androgen receptor-interacting protein HSPBAP1 facilitates growth of...
Published: October, 2014

Abstract: Hormonal therapies targeting androgen receptor (AR) are effective in prostate cancer (PCa), but often the cancers progress to fatal castrate-resist... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Enantioselective regulation of lactate racemization by LarR in Lact...
Published: October, 2014

Abstract: Lactobacillus plantarum is a lactic acid bacterium that produces a racemic mixture of L- and D-lactate from sugar fermentation. The inter-conversio... Read more »

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Bioruptor Cell Lysis

Loss of Nucleolar Histone Chaperone NPM1 Triggers Rearrangement of ...
Published: October, 2014

Abstract: Nucleoli are prominent nuclear structures assembled and organized around actively transcribed ribosomal DNA (rDNA). The nucleolus has emerged as a ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

BET bromodomain inhibition suppresses transcriptional responses to ...
Published: October, 2014

Abstract: Disruption of the interaction of bromo and extraterminal (BET) proteins with acetylated histones using small molecule inhibitors suppresses Myc-dri... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Zinc finger protein Zfp335 is required for the formation of the naï...
Published: October, 2014

Abstract: The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood.... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Epigenetic regulation of inflammatory gene expression in macrophage...
Published: October, 2014

Abstract: Acetylation of histone and non-histone proteins by histone acetyltransferases plays a pivotal role in the expression of proinflammatory genes. Give... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A B-cell targeting virus disrupts potentially protective genomic me...
Published: October, 2014

Abstract: The mechanisms by which viruses modulate the immune system include changes in host genomic methylation. 5-hydroxmethylcytosine (5hmC) is the cataly... Read more »

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Antibody 5mC (C15200081)

AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 ...
Published: October, 2014

Abstract: The recognition of modified histones by "reader" proteins constitutes a key mechanism regulating gene expression in the chromatin context. Compared... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Precision microbiome reconstitution restores bile acid mediated res...
Published: October, 2014

Abstract: The gastrointestinal tracts of mammals are colonized by hundreds of microbial species that contribute to health, including colonization resistance ... Read more »

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Bioruptor Cell Lysis Mass Spectrometry

Next Generation Sequencing Identifies a Novel Rearrangement in the ...
Published: October, 2014

Abstract: Genetic testing for hemoglobinopathies is required for prenatal diagnosis, understanding complex cases where multiple pathogenic variants may be pr... Read more »

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DNA shearing Bioruptor

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintena...
Published: October, 2014

Abstract: A fraction of cancer cells maintain telomeres through the telomerase-independent, 'Alternative Lengthening of Telomeres' (ALT) pathway. ALT relies ... Read more »

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DNA shearing Bioruptor

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical m...
Published: October, 2014

Abstract: The androgen receptor (AR) plays a central role in establishing an oncogenic cascade that drives prostate cancer progression. Some prostate cancers... Read more »

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Antibody

Prenatal stress-induced programming of genome-wide promoter DNA met...
Published: October, 2014

Abstract: The serotonin transporter gene (5-HTT/SLC6A4)-linked polymorphic region has been suggested to have a modulatory role in mediating effects of early-... Read more »

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DNA shearing

Polycomb Repressive Complex 2 Regulates Lineage Fidelity during Emb...
Published: October, 2014

Abstract: Polycomb Repressive Complex 2 (PRC2) catalyzes histone H3 lysine 27 tri-methylation (H3K27me3), an epigenetic modification associated with gene rep... Read more »

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Bioruptor Chromatin Shearing ChIP-seq IP-Star

The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B c...
Published: October, 2014

Abstract: A single microRNA (miRNA) can regulate the expression of many genes, though the level of repression imparted on any given target is generally low. ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Biogeochemical Typing of Paddy Field by a Data-Driven Approach Reve...
Published: October, 2014

Abstract: We propose the technique of biogeochemical typing (BGC typing) as a novel methodology to set forth the sub-systems of organismal communities associ... Read more »

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Bioruptor

In vivo interrogation of gene function in the mammalian brain using...
Published: October, 2014

Abstract: Probing gene function in the mammalian brain can be greatly assisted with methods to manipulate the genome of neurons in vivo. The clustered, regul... Read more »

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Bioruptor Cell Lysis Western Blot

Transforming Growth Factor β1 (TGF-β1) Enhances Expression of Profi...
Published: October, 2014

Abstract: Increased expression of transforming growth factor-β1 (TGF-β1) in glomerular mesangial cells (MC) augments extracellular matrix accumulation and hy... Read more »

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Bioruptor Cell Lysis Western Blot

A nanobody modulates the p53 transcriptional program without pertur...
Published: October, 2014

Abstract: The p53 transcription factor plays an important role in genome integrity. To perform this task, p53 regulates the transcription of genes promoting ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Drosophila oncogene Gas41 is RNAi modulator that intersects heteroc...
Published: October, 2014

Abstract: Glioma amplified sequence41 (Gas41) is a highly conserved putative transcription factor that is frequently abundant in human gliomas. Gas41 shows o... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative S...
Published: October, 2014

Abstract: Increased cellular levels of oxidative stress are implicated in a large number of human diseases. Here we describe the transcription co-factor KDM5... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Drosophila oncogene Gas41 is an RNA interference modulator that int...
Published: October, 2014

Abstract: Glioma amplified sequence41 (Gas41) is a highly conserved putative transcription factor that is frequently abundant in human gliomas. Gas41 shows o... Read more »

Allelic expression mapping across cellular lineages to establish im...
Published: October, 2014

Abstract: Most complex disease-associated genetic variants are located in non-coding regions and are therefore thought to be regulatory in nature. Associatio... Read more »

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Antibody H3K4me3 (C15410003)

Sperm DNA Methylation Analysis in Swine Reveals Conserved and Speci...
Published: October, 2014

Abstract: Male infertility is an increasing health issue in today's society, for both human or livestock populations. In livestock, male infertility slows th... Read more »

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DNA shearing Bioruptor IPure kit

Neural crest specification and migration independently require NSD3...
Published: October, 2014

Abstract: Neural crest precursors express genes that cause them to become migratory, multipotent cells, distinguishing them from adjacent stationary neural p... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Involvement of microRNA-24 and DNA Methylation in Resistance of Nas...
Published: October, 2014

Abstract: Nasopharyngeal carcinoma (NPC) is a malignant tumor originating in the epithelium. Radiotherapy is the standard therapy, but tumor resistance to th... Read more »

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MagMeDIP kit

Primate-specific endogenous retrovirus-driven transcription defines...
Published: October, 2014

Abstract: Naive embryonic stem cells hold great promise for research and therapeutics as they have broad and robust developmental potential. While such cells... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

ASCL1 is a lineage oncogene providing therapeutic targets for high-...
Published: October, 2014

Abstract: Aggressive neuroendocrine lung cancers, including small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), represent an understudied t... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Cross-talking noncoding RNAs contribute to cell-specific neurodegen...
Published: October, 2014

Abstract: What causes the tissue-specific pathology of diseases resulting from mutations in housekeeping genes? Specifically, in spinocerebellar ataxia type ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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