Publications,References

Alterations of epigenetic signatures in hepatocyte nuclear factor 4...
Published: January, 2014

Abstract: Hepatocyte nuclear factor 4α (HNF4α) is a liver-enriched transcription factor essential for liver development and function. In hepatocytes, HNF4α r... Read more »

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Antibody 5mC (C15200081)

Peroxisome proliferator-activated receptor γ regulates genes involv...
Published: January, 2014

Abstract: The nuclear receptor peroxisome proliferator-activated receptor (PPAR) is a transcription factor whose expression is induced during adipogenesis an... Read more »

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DNA shearing Bioruptor Antibody 5mC (C15200081)

LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neurona...
Published: January, 2014

Abstract: Basal forebrain cholinergic neurons play an important role in cognitive functions such as learning and memory, and they are affected in several neu... Read more »

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LowCell ChIP kit

SPBP is a sulforaphane induced transcriptional coactivator of NRF2 ...
Published: January, 2014

Abstract: Organisms exposed to oxidative stress respond by orchestrating a stress response to prevent further damage. Intracellular levels of antioxidant age... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Pan-histone demethylase inhibitors simultaneously targeting Jumonji...
Published: January, 2014

Abstract: In prostate cancer, two different types of histone lysine demethylases (KDM), LSD1/KDM1 and JMJD2/KDM4, are coexpressed and colocalize with the and... Read more »

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Antibody H3K4me3 (C15410003)

Quiescent hepatic stellate cells functionally contribute to the hep...
Published: January, 2014

Abstract: Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling has numerous funct... Read more »

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Antibody

Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of...
Published: January, 2014

Abstract: Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that is implicated in plethora of biological processes, includ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

mRNA levels of related Abcb genes change opposite to each other upo...
Published: January, 2014

Abstract: The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious prob... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

DUSP1 is a novel target for enhancing pancreatic cancer cell sensit...
Published: January, 2014

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with a poor prognosis that is characterized by excessive mitogenic pathway activation an... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The thyroid hormone receptor β induces DNA damage and premature sen...
Published: January, 2014

Abstract: There is increasing evidence that the thyroid hormone (TH) receptors (THRs) can play a role in aging, cancer and degenerative diseases. In this pap... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A role for FACT in repopulation of nucleosomes at inducible genes.
Published: January, 2014

Abstract: Xenobiotic drugs induce Pleiotropic Drug Resistance (PDR) genes via the orthologous Pdr1/Pdr3 transcription activators. We previously identified th... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cau...
Published: January, 2014

Abstract: Dowling-Degos disease (DDD) is an autosomal-dominant genodermatosis characterized by progressive and disfiguring reticulate hyperpigmentation. We p... Read more »

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DNA shearing Bioruptor

Histone deacetylase inhibition with valproic acid downregulates ost...
Published: January, 2014

Abstract: Adult mesenchymal stem cells, such as dental pulp stem cells, are of great interest for cell-based tissue engineering strategies because they can d... Read more »

Hypermethylation of the alternative AWT1 promoter in hematological ...
Published: January, 2014

Abstract: BACKGROUND: Wilms tumor 1 (WT1) is over-expressed in numerous cancers with respect to normal cells, and has either a tumor suppressor or oncogenic ... Read more »

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Antibody

CLOCK:BMAL1 is a pioneer-like transcription factor.
Published: January, 2014

Abstract: The mammalian circadian clock relies on the master genes CLOCK and BMAL1 to drive rhythmic gene expression and regulate biological functions under ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

Integrated transcriptome analysis of mouse spermatogenesis.
Published: January, 2014

Abstract: BACKGROUND: Differentiation of primordial germ cells into mature spermatozoa proceeds through multiple stages, one of the most important of which i... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The genome-wide landscape of DNA methylation and hydroxymethylation...
Published: January, 2014

Abstract: Sleep is critical for normal brain function and mental health. However, the molecular mechanisms mediating the impact of sleep loss on both cogniti... Read more »

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DNA shearing Bioruptor

Genome-wide profiling of transcription factor binding and epigeneti...
Published: January, 2014

Abstract: The recent advances in high-throughput sequencing combined with various other technologies have allowed detailed and genome-wide insight into the t... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Genome-wide data (ChIP-seq) enabled identification of cell wall-rel...
Published: January, 2014

Abstract: BACKGROUND: Identifying the target genes of transcription factors is important for unraveling regulatory networks in all types of organisms. Our in... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Analyzing the functions and structure of the human lipodystrophy pr...
Published: January, 2014

Abstract: Disruption of the gene BSCL2, which encodes the protein seipin, causes severe generalized lipodystrophy in humans with a near complete absence of a... Read more »

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Bioruptor Cell Lysis

Microbes in the neonatal intensive care unit resemble those found i...
Published: January, 2014

Abstract: BACKGROUND: The source inoculum of gastrointestinal tract (GIT) microbes is largely influenced by delivery mode in full-term infants, but these inf... Read more »

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DNA shearing Bioruptor

Differential methylation of the TRPA1 promoter in pain sensitivity.
Published: January, 2014

Abstract: Chronic pain is a global public health problem, but the underlying molecular mechanisms are not fully understood. Here we examine genome-wide DNA m... Read more »

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DNA shearing Bioruptor IP-Star MagMeDIP kit

Negative regulation of the peptidylarginine deiminase type IV promo...
Published: January, 2014

Abstract: High titers of anti-citrullinated protein/peptide antibodies (ACPAs) have been detected in sera of rheumatoid arthritis (RA) patients, implicating ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Differential expression of histone H3 genes and selective associati...
Published: January, 2014

Abstract: BACKGROUND: Regulation of chromatin structure involves deposition of selective histone variants into nucleosome arrays. Numerous histone H3 variant... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Array-based assay detects genome-wide 5-mC and 5-hmC in the brains ...
Published: January, 2014

Abstract: BACKGROUND: Methylation on the fifth position of cytosine (5-mC) is an essential epigenetic mark that is linked to both normal neurodevelopment and... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (20...
Published: January, 2014

Abstract: BACKGROUND: Acute respiratory infections represent a serious public health issue worldwide but virological aetiologies of Influenza Like Illnesses ... Read more »

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DNA shearing Bioruptor

Strand-specific RNA-Seq reveals widespread and developmentally regu...
Published: January, 2014

Abstract: BACKGROUND: Advances in high-throughput sequencing have led to the discovery of widespread transcription of natural antisense transcripts (NATs) in... Read more »

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DNA shearing Bioruptor

Histone Deacetylase inhibition with Valproic Acid down-regulates Os...
Published: January, 2014

Abstract: Adult mesenchymal stem cells, such as dental pulp stem cells, are of great interest for cell-based tissue engineering strategies because they can d... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Demethylation of the human eotaxin-3 gene promoter leads to the ele...
Published: January, 2014

Abstract: DNA demethylation has been primarily studied in the context of development biology, cell fate, and cancer, with less attention on inflammation. In ... Read more »

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IP-Star IP-Star Compact

Histone Deacetylase Classes I and II Regulate Kaposi's Sarcoma-Asso...
Published: January, 2014

Abstract: In primary effusion lymphoma (PEL) cells infected with latent Kaposi's sarcoma-associated herpesvirus (KSHV), the promoter of the viral lytic switc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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