Publications,References

The 5p12 breast cancer susceptibility locus affects MRPS30 expressi...
Published: March, 2014

Abstract: Genome-wide association studies have identified numerous loci linked to breast cancer susceptibility, but the mechanism by which variations at thes... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells.
Published: February, 2014

Abstract: Signal transducers and activators of transcription 5(STAT5) are cytokine induced signaling proteins, which regulate key immunological processes, su... Read more »

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LowCell ChIP kit

A recently evolved class of alternative 3'-terminal exons involved ...
Published: February, 2014

Abstract: Alternative 3'-terminal exons, which use intronic polyadenylation sites, are generally less conserved and expressed at lower levels than the last e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Broadly permissive intestinal chromatin underlies lateral inhibitio...
Published: February, 2014

Abstract: Cells differentiate when transcription factors bind accessible cis-regulatory elements to establish specific gene expression programs. In different... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Mutant astrocytes differentiated from Rett syndrome patients-specif...
Published: February, 2014

Abstract: The disease mechanism of Rett syndrome (RTT) is not well understood. Studies in RTT mouse models have suggested a non-cell-autonomous role for astr... Read more »

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Antibody

Epigenomic alterations define lethal CIMP-positive ependymomas of i...
Published: February, 2014

Abstract: Ependymomas are common childhood brain tumours that occur throughout the nervous system, but are most common in the paediatric hindbrain. Current s... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K27me3 (C15410069)

Pharmacological inhibition of EZH2 as a promising differentiation t...
Published: February, 2014

Abstract: Background Embryonal Rhabdomyosarcoma (RMS) is a pediatric soft-tissue sarcoma derived from myogenic precursors that is characterized by a good p... Read more »

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Antibody

Maintenance of Heterochromatin Boundary and Nucleosome Composition ...
Published: February, 2014

Abstract: Chromatin remodeling complexes cooperate to regulate gene promoters and to define chromatin neighborhoods. Here, we identified genetic and function... Read more »

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Bioruptor Chromatin Shearing

Epigenetic upregulation of endogenous VEGF-A reduces myocardial inf...
Published: February, 2014

Abstract: "Epigenetherapy" alters epigenetic status of the targeted chromatin and modifies expression of the endogenous therapeutic gene. In this study we us... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Epigenetics of Human Myometrium: DNA Methylation of Genes Encoding ...
Published: February, 2014

Abstract: Preterm birth involves the interaction of societal and environmental factors potentially modulating the length of gestation via the epigenome. An e... Read more »

Sequencing-based large-scale genomics approaches with small numbers...
Published: February, 2014

Abstract: High-throughput sequencing has become the large-scale approach of choice to study global gene expression and the distribution of specific chromatin... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Reversible Top1 cleavage complexes are stabilized strand-specifical...
Published: February, 2014

Abstract: Various topological constraints at the ribosomal DNA (rDNA) locus impose an extra challenge for transcription and DNA replication, generating const... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The FOS transcription factor family differentially controls trophob...
Published: February, 2014

Abstract: Extravillous trophoblast invasion is a fundamental component of human placentation. Invading trophoblast cells promote blood flow to the conceptus ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Myc and max genome-wide binding sites analysis links the Myc regula...
Published: February, 2014

Abstract: Myc is a master transcription factor that has been demonstrated to be required for embryonic stem cell (ESC) pluripotency, self-renewal, and inhibi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Epigenetics meets genetics in acute myeloid leukemia: clinical impa...
Published: February, 2014

Abstract: PURPOSE: Molecular risk stratification of acute myeloid leukemia (AML) is largely based on genetic markers. However, epigenetic changes, including ... Read more »

Geriatric muscle stem cells switch reversible quiescence into senes...
Published: February, 2014

Abstract: Regeneration of skeletal muscle depends on a population of adult stem cells (satellite cells) that remain quiescent throughout life. Satellite cell... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit

Runx1t1 (Runt-related transcription factor 1; translocated to, 1) e...
Published: February, 2014

Abstract: BACKGROUND: Microglia, the resident immune cells of the brain, undergo rapid proliferation and produce several proinflammatory molecules and nitric... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Glial wingless/Wnt regulates glutamate receptor clustering and syna...
Published: February, 2014

Abstract: Glial cells are emerging as important regulators of synapse formation, maturation, and plasticity through the release of secreted signaling molecul... Read more »

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Bioruptor Chromatin Shearing

The long non-coding RNA Paupar regulates the expression of both loc...
Published: February, 2014

Abstract: Although some long noncoding RNAs (lncRNAs) have been shown to regulate gene expression in cis, it remains unclear whether lncRNAs can directly reg... Read more »

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DNA shearing Bioruptor

Genome-wide binding patterns of thyroid hormone receptor beta.
Published: February, 2014

Abstract: Thyroid hormone (TH) receptors (TRs) play central roles in metabolism and are major targets for pharmaceutical intervention. Presently, however, th... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Long-term parental methamphetamine exposure of mice influences beha...
Published: February, 2014

Abstract: The high rate of methamphetamine (METH) abuse among young adults and women of childbearing age makes it imperative to determine the long-term effec... Read more »

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DNA shearing Bioruptor Antibody 5mC (C15200081)

CDK phosphorylation of SLD-2 is required for replication initiation...
Published: February, 2014

Abstract: Cyclin-dependent kinase (CDK) plays a vital role in proliferation control across eukaryotes. Despite this, how CDK mediates cell cycle and developm... Read more »

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Bioruptor Cell Lysis Western Blot

Reduced Euchromatin histone methyltransferase 1 causes developmenta...
Published: February, 2014

Abstract: Haploinsufficiency of Euchromatin histone methyltransferase 1 (EHMT1), a chromatin modifying enzyme, is the cause of Kleefstra syndrome (KS). KS is... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Sp1 and Sp3 transcription factors regulate the basal expression of ...
Published: February, 2014

Abstract: Microsomal epoxide hydrolase (mEH, EPHX1) is a critical biotransformation enzyme, catalyzing the metabolism of many xenobiotics. Human mEH is trans... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

C/EBPα poises B cells for rapid reprogramming into induced pluripot...
Published: February, 2014

Abstract: CCAAT/enhancer binding protein-α (C/EBPα) induces transdifferentiation of B cells into macrophages at high efficiencies and enhances reprogramming ... Read more »

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DNA shearing Bioruptor

Nonstochastic reprogramming from a privileged somatic cell state.
Published: February, 2014

Abstract: Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and inefficient and is thought to be a stochastic process. ... Read more »

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DNA shearing Bioruptor

BayMeth: Improved DNA methylation quantification for affinity captu...
Published: February, 2014

Abstract: DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, su... Read more »

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MethylCap

A deterministic analysis of genome integrity during neoplastic grow...
Published: February, 2014

Abstract: The development of cancer has been associated with the gradual acquisition of genetic alterations leading to a progressive increase in malignancy. ... Read more »

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DNA shearing Bioruptor Bioruptor Plus

Sumoylation of the THO complex regulates the biogenesis of a subset...
Published: February, 2014

Abstract: Assembly of messenger ribonucleoparticles (mRNPs) is a pivotal step in gene expression, but only a few molecular mechanisms contributing to its reg... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

c-Myc-dependent transcriptional regulation of cell cycle and nucleo...
Published: February, 2014

Abstract: Oligodendrocyte progenitor cells (OPCs) have the ability to divide or to growth arrest and differentiate into myelinating oligodendrocytes in the d... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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