Publications,References

The polycomb protein Ezh2 regulates differentiation and plasticity ...
Published: November, 2013

Abstract: After antigen encounter by CD4(+) T cells, polarizing cytokines induce the expression of master regulators that control differentiation. Inactivati... Read more »

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Antibody

Structural variation-associated expression changes are paralleled b...
Published: November, 2013

Abstract: UNLABELLED: Copy number variants (CNVs) influence the expression of genes that map not only within the rearrangement, but also to its flanks. To as... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Drosophila UTX Coordinates with p53 to Regulate ku80 Expression in ...
Published: November, 2013

Abstract: UTX is known as a general factor that activates gene transcription during development. Here, we demonstrate an additional essential role of UTX in ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Dynamic reprogramming of 5-hydroxymethylcytosine during early porci...
Published: November, 2013

Abstract: DNA active demethylation is an important epigenetic phenomenon observed in porcine zygotes, yet its molecular origins are unknown. Our results show... Read more »

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Antibody

Frequent alteration of the protein synthesis of enzymes for glucose...
Published: November, 2013

Abstract: BACKGROUND: Cancer cells show enhanced glycolysis and inhibition of oxidative phosphorylation, even in the presence of sufficient oxygen (aerobic g... Read more »

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Bioruptor Tissue Homogenization

Comparative analysis of affinity-based 5-hydroxymethylation enrichm...
Published: November, 2013

Abstract: The epigenetic modification of 5-hydroxymethylcytosine (5hmC) is receiving great attention due to its potential role in DNA methylation reprogrammi... Read more »

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DNA shearing Bioruptor

High-resolution microbial community reconstruction by integrating s...
Published: November, 2013

Abstract: The emergence of massively parallel sequencing technology has revolutionized microbial profiling, allowing the unprecedented comparison of microbia... Read more »

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DNA shearing Bioruptor

Repression of RNA polymerase I upon stress is caused by inhibition ...
Published: November, 2013

Abstract: Sirtuins are NAD(+)-dependent protein deacetylases that connect metabolism and cellular homeostasis. Here we show that the nuclear Sirtuin SIRT7 ta... Read more »

MAP Kinase Signaling Mediates Phosphorylation of Polycomb Ortholog ...
Published: November, 2013

Abstract: Cbx7 is one of five mammalian orthologs of the Drosophila Polycomb (Pc). Cbx7 recognizes methylated lysine residues on the histone H3 tail and cont... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Integrated analysis of transcript-level regulation of metabolism re...
Published: November, 2013

Abstract: Metabolic diseases and comorbidities represent an ever-growing epidemic where multiple cell types impact tissue homeostasis. Here, the link between... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

LXRs regulate ER stress and inflammation through dynamic modulation...
Published: November, 2013

Abstract: The fatty acyl composition of phospholipids determines the biophysical character of membranes and impacts the function of membrane proteins. Here, ... Read more »

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Master Mix

Insulin-dependent transcriptional control in L6 rat myotubes is ass...
Published: November, 2013

Abstract: Besides its direct metabolic effects, insulin induces transcriptional alterations in its target tissues. However, whether such changes are accompan... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Dynamic CCAAT/Enhancer Binding Protein-Associated Changes of DNA Me...
Published: November, 2013

Abstract: DNA methylation patterns are maintained in adult somatic cells. Recent findings, however, suggest that all methylation patterns are not preserved. ... Read more »

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Antibody LowCell ChIP kit

Coupling transcription factor occupancy to nucleosome architecture ...
Published: November, 2013

Abstract: It is currently not possible to resolve the genome-wide relationship of transcription factors (TFs) and nucleosomes at the level of individual chro... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Histone deacetylase 3 coordinates commensal-bacteria-dependent inte...
Published: November, 2013

Abstract: The development and severity of inflammatory bowel diseases and other chronic inflammatory conditions can be influenced by host genetic and environ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vi...
Published: November, 2013

Abstract: The Atlantic cod (Gadus morhua) is an economically important species commonly consumed by humans. The widespread distribution of cod in the North A... Read more »

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Bioruptor Tissue Homogenization Bioruptor Plus

Pattern of heat shock factor and heat shock protein expression in l...
Published: November, 2013

Abstract: Bipolar disorder (BD), a stress-related disease, is characterized by altered glucocorticoid receptor (GR) signalling. Stress response includes acti... Read more »

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Antibody

Promiscuous RNA binding by Polycomb repressive complex 2.
Published: November, 2013

Abstract: Polycomb repressive complex 2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long noncoding... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidyl...
Published: November, 2013

Abstract: The MEF2-class IIa histone deacetylase (HDAC) axis operates in several differentiation pathways and in numerous adaptive responses. We show here th... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Regulation of hypothalamic corticotropin-releasing hormone transcri...
Published: November, 2013

Abstract: Negative glucocorticoid feedback is essential for preventing the deleterious effects of excessive hypothalamic pituitary adrenal axis axis activati... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genomic and proteomic analyses of prdm5 reveal interactions with in...
Published: November, 2013

Abstract: PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess hi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus

A chromatin immunoprecipitation (ChIP) protocol for use in whole hu...
Published: November, 2013

Abstract: Chromatin immunoprecipitation (ChIP) has become a central method when studying in vivo protein-DNA interactions, with the major challenge being the... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Expression and regulation of intergenic long noncoding RNAs during ...
Published: November, 2013

Abstract: Although intergenic long noncoding RNAs (lincRNAs) have been linked to gene regulation in various tissues, little is known about lincRNA transcript... Read more »

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DNA shearing Bioruptor

Lipopolysaccharide Increases the Incidence of Collagen-Induced Arth...
Published: November, 2013

Abstract: OBJECTIVE: The protease HTRA-1 is closely associated with rheumatoid arthritis (RA). The molecular mechanisms that control HTRA-1 expression are cu... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

PRC2 binds active promoters and contacts nascent RNAs in embryonic ...
Published: November, 2013

Abstract: EZH2 is the catalytic subunit of PRC2, a central epigenetic repressor essential for development processes in vivo and for the differentiation of em... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Live visualization of chromatin dynamics with fluorescent TALEs.
Published: November, 2013

Abstract: The spatiotemporal organization of genomes in the nucleus is an emerging key player to regulate genome function. Live imaging of nuclear organizati... Read more »

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Antibody

Mitochondrial-related proteomic changes during obesity and fasting ...
Published: November, 2013

Abstract: Although mitochondrial dysfunction is implicated in the pathogenesis of obesity, the molecular mechanisms underlying obesity-related metabolic abno... Read more »

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Bioruptor

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer ...
Published: November, 2013

Abstract: Prostate cancers remain indolent in the majority of individuals but behave aggressively in a minority. The molecular basis for this clinical hetero... Read more »

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Bioruptor Chromatin Shearing

Dynamics of 1α,25-dihydroxyvitamin D3-dependent chromatin accessibi...
Published: November, 2013

Abstract: The signaling cascade of the transcription factor vitamin D receptor (VDR) is triggered by its specific ligand 1α,25-dihydroxyvitamin D3 (1α,25(OH)... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Mouse BAZ1A (ACF1) is dispensable for double-strand break repair bu...
Published: November, 2013

Abstract: ATP-dependent chromatin remodelers control DNA access for transcription, recombination, and other processes. Acf1 (also known as BAZ1A in mammals) ... Read more »

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Bioruptor Cell Lysis Western Blot

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