Publications,References

The Emerging Role of SOX2 in Cell Proliferation and Survival and It...
Published: December, 2013

Abstract: Tumor cells have long been observed to share several biological characteristics with normal stem/progenitor cells; however, the oncogenic mechanism... Read more »

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LowCell ChIP kit

ZRF1 controls the retinoic acid pathway and regulates leukemogenic ...
Published: December, 2013

Abstract: Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell p... Read more »

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Bioruptor Cell Lysis Antibody

Distinctive patterns of epigenetic marks are associated with promot...
Published: December, 2013

Abstract: BACKGROUND: The long terminal repeat (LTR) retrotransposons and the non-LTR retrotransposons (LINE-1 or L1) make up more than one-third of the mous... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Elevated levels of FOXA1 facilitate androgen receptor chromatin bin...
Published: December, 2013

Abstract: Castration-resistant prostate cancer (CRPC) continues to pose a significant clinical challenge with new generation second-line hormonal therapies a... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Transcription factor occupancy can mediate active turnover of DNA m...
Published: December, 2013

Abstract: Distal regulatory elements, including enhancers, play a critical role in regulating gene activity. Transcription factor binding to these elements c... Read more »

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DNA shearing Bioruptor

The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pat...
Published: December, 2013

Abstract: Cyclin-dependent kinase 9 (Cdk9) promotes elongation by RNA polymerase II (RNAPII), mRNA processing, and co-transcriptional histone modification. C... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide analysis of DNA methylation changes induced by gestatio...
Published: December, 2013

Abstract: Inorganic arsenic is known to be a human carcinogen. Previous studies have reported that DNA methylation changes are involved in arsenic-induced ca... Read more »

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Antibody

Rapid Transposon Liquid Enrichment Sequencing (TnLE-seq) for Gene F...
Published: December, 2013

Abstract: Whole-genome fitness analysis in microbes that uses saturating transposon mutagenesis combined with massively parallel sequencing (Tn-seq) is provi... Read more »

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DNA shearing Bioruptor

Alternative End-Joining and Classical Nonhomologous End-Joining Pat...
Published: December, 2013

Abstract: Classical nonhomologous end-joining (C-NHEJ) and alternative end-joining (A-EJ) are the main DNA double-strand break (DSB) repair pathways when a s... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Hitchhiker antigens: Inconsistent ChIP results, questionable immuno...
Published: December, 2013

Abstract: Questionable data and poor antibody performance may have a common factor: antigens "hitchhiking" on the very antibodies designed to target them. He... Read more »

A key role for EZH2 in epigenetic silencing of HOX genes in mantle ...
Published: December, 2013

Abstract: The chromatin modifier EZH2 is overexpressed and associated with inferior outcome in mantle cell lymphoma (MCL). Recently, we demonstrated preferen... Read more »

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Antibody H3K27me3 (C15410069)

The T antigen locus of merkel cell polyomavirus downregulates human...
Published: December, 2013

Abstract: Establishment of a chronic infection is a key event in virus-mediated carcinogenesis. Several cancer-associated, double-stranded DNA (dsDNA) viruse... Read more »

Two Histone Deacetylases, FfHda1 and FfHda2, Are Important for Fusa...
Published: December, 2013

Abstract: Histone modifications are crucial for the regulation of secondary metabolism in various filamentous fungi. Here we studied the involvement of histo... Read more »

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Bioruptor Bioruptor Plus

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone t...
Published: December, 2013

Abstract: Individuals carrying (GGGGCC) expanded repeats in the C9orf72 gene represent a significant portion of patients suffering from amyotrophic lateral s... Read more »

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Antibody

Genome-wide chromatin analysis in mature mouse and human spermatozoa.
Published: December, 2013

Abstract: At the end of mammalian spermatogenesis, chromatin in differentiating germ cells is extensively remodeled, with the majority of nucleosomes being r... Read more »

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Bioruptor Bioruptor Plus

The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-...
Published: December, 2013

Abstract: The TGF-β/Smad3 pathway plays a major role in tissue fibrosis, but the precise mechanisms are not fully understood. Here we identified microRNA miR... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mediator links transcription and DNA repair by facilitating Rad2/XP...
Published: December, 2013

Abstract: Mediator is a large multiprotein complex conserved in all eukaryotes. The crucial function of Mediator in transcription is now largely established.... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Oral administration of transforming growth factor-β1 (TGF-β1) prote...
Published: November, 2013

Abstract: Inflammatory immune responses play an important role in mucosal homeostasis and gut diseases. Nuclear factor κB (NF-κB), central to the proinflamma... Read more »

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Bioruptor Chromatin Shearing

BORIS/CTCFL is an RNA-binding protein that associates with polysomes.
Published: November, 2013

Abstract: BACKGROUND: BORIS (CTCFL), a paralogue of the multifunctional and ubiquitously expressed transcription factor CTCF, is best known for its role in t... Read more »

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Bioruptor Cell Lysis

A closed-loop synthetic gene circuit for the treatment of diet-indu...
Published: November, 2013

Abstract: Diet-induced obesity is a lifestyle-associated medical condition that increases the risk of developing cardiovascular disease, type 2 diabetes and ... Read more »

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Bioruptor Bioruptor Plus

Toxoplasma gondii inhibits IFN-γ- and IFN-β-induced host cell STAT1...
Published: November, 2013

Abstract: The IFN-γ response, mediated by the STAT1 transcription factor, is crucial for host defense against the intracellular pathogen Toxoplasma gon... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star

A quantitative telomeric chromatin isolation protocol identifies di...
Published: November, 2013

Abstract: Telomere composition changes during tumourigenesis, aging and in telomere syndromes in a poorly defined manner. Here we develop a quantitative telo... Read more »

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Bioruptor Chromatin Shearing

Reactive Oxygen Species Induce Epigenetic Instability through the F...
Published: November, 2013

Abstract: Chronic hepatitis C (CHC) triggers oxidative stress and contributes to the emergence of hepatocellular carcinoma (HCC). We previously reported that... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star

The nuclear receptor Rev-erbα controls circadian thermogenic plasti...
Published: November, 2013

Abstract: Circadian oscillation of body temperature is a basic, evolutionarily conserved feature of mammalian biology. In addition, homeostatic pathways allo... Read more »

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Bioruptor Tissue Homogenization

Transcriptome surveillance by selective termination of noncoding RN...
Published: November, 2013

Abstract: Pervasive transcription of eukaryotic genomes stems to a large extent from bidirectional promoters that synthesize mRNA and divergent noncoding RNA... Read more »

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Bioruptor Cell Lysis

The cohesin complex regulates immunoglobulin class switch recombina...
Published: November, 2013

Abstract: Immunoglobulin (Ig) class switch recombination (CSR) is initiated by the transcription-coupled recruitment of activation-induced cytidine deaminase... Read more »

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IPure kit

Suggestive linkage of familial mesial temporal lobe epilepsy to chr...
Published: November, 2013

Abstract: PURPOSE: To describe the clinical findings in a family with a benign form of mesial temporal lobe epilepsy and to identify the causative genetic fa... Read more »

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DNA shearing Bioruptor

PRH/HHex inhibits the migration of breast and prostate epithelial c...
Published: November, 2013

Abstract: PRH/HHex (proline-rich homeodomain protein) is a transcription factor that controls cell proliferation and cell differentiation in a variety of tis... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Pluripotency factors and Polycomb Group proteins repress aryl hydro...
Published: November, 2013

Abstract: The aryl hydrocarbon receptor (AHR) is a transcription factor and environmental sensor that regulates expression of genes involved in drug-metaboli... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Promoter Hypomethylation of EpCAM-Regulated Bone Morphogenetic Prot...
Published: November, 2013

Abstract: PURPOSE: Epigenetic regulation by promoter methylation plays a key role in tumorigenesis. Our goal was to investigate whether altered DNA methylati... Read more »

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Antibody

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