Publications,References

LL37/self-DNA complexes mediate monocyte reprogramming
Published: August, 2024

Abstract: LL37 alone and in complex with self-DNA triggers inflammatory responses in myeloid cells and plays a crucial role in the development of systemic au... Read more »

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Antibody

Epigenetic alterations affecting hematopoietic regulatory networks ...
Published: July, 2024

Abstract: Leukemias with ambiguous lineage comprise several loosely defined entities, often without a clear mechanistic basis. Here, we extensively profile t... Read more »

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Antibody Microplex Library Preparation kit

The landscape of RNA-chromatin interaction reveals small non-coding...
Published: June, 2024

Abstract: RNA constitutes a large fraction of chromatin. Spatial distribution and functional relevance of most of RNA-chromatin interactions remain unknown. ... Read more »

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Bioruptor Antibody iDeal ChIP-seq Kit for Transcription Factors iDeal ChIP-seq Kit for Histones

Epigenomic signatures of sarcomatoid differentiation to guide the t...
Published: June, 2024

Abstract: Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and a heightened response to immune checkpoint inhibi... Read more »

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MagMeDIP kit Antibody IPure kit

KRAS promotes GLI2-dependent transcription during pancreatic carcin...
Published: June, 2024

Abstract: Aberrant activation of GLI transcription factors has been implicated in the pathogenesis of different tumor types including pancreatic ductal adeno... Read more »

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Antibody

Detecting small cell transformation in patients with advanced EGFR ...
Published: June, 2024

Abstract: Purpose: Histologic transformation to small cell lung cancer (SCLC) is a mechanism of treatment resistance in patients with advanced oncogene-drive... Read more »

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MagMeDIP kit IPure kit

Single-cell epigenomic reconstruction of developmental trajectories...
Published: June, 2024

Abstract: Cell fate progression of pluripotent progenitors is strictly regulated, resulting in high human cell diversity. Epigenetic modifications also orche... Read more »

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Bioruptor Antibody

Prostate cancer detection through unbiased capture of methylated ce...
Published: June, 2024

Abstract: Prostate cancer screening using prostate-specific antigen (PSA) has been shown to reduce mortality but with substantial overdiagnosis, leading to u... Read more »

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MagMeDIP kit IPure kit

The ETO2 transcriptional cofactor maintains acute leukemia by drivi...
Published: June, 2024

Abstract: Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating tran... Read more »

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IPure kit

Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024

Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »

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Antibody

Master corepressor inactivation through multivalent SLiM-induced po...
Published: June, 2024

Abstract: While the elucidation of regulatory mechanisms of folded proteins is facilitated due to their amenability to high-resolution structural characteriz... Read more »

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Antibody

Brassica rapa CURLY LEAF is a major H3K27 methyltransferase regulat...
Published: June, 2024

Abstract: Main conclusion In Brassica rapa, the epigenetic modifier BraA.CLF orchestrates flowering by modulating H3K27me3 levels at the floral integra... Read more »

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Antibody

Disease related changes in ATAC-seq of iPSC-derived motor neuron li...
Published: May, 2024

Abstract: Amyotrophic Lateral Sclerosis (ALS), like many other neurodegenerative diseases, is highly heritable, but with only a small fraction of cases expla... Read more »

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ATAC-seq

Positive and negative feedback regulation of the TGF-β1 explains tw...
Published: April, 2024

Abstract: During aging, skin homeostasis is essential for maintaining appearance, as well as biological defense of the human body. In this study, we identi... Read more »

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iDeal ChIP-seq Kit for Histones

Cis-regulatory interfaces reveal the molecular mechanisms underlyin...
Published: April, 2024

Abstract: Tissue-specific gene expression is fundamental in development and evolution, and is mediated by transcription factors and by the cis-regulator... Read more »

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CRISPR

Systematic mapping of TF-mediated cell fate changes by a pooled ind...
Published: April, 2024

Abstract: Transcriptional regulation controls cellular functions through interactions between transcription factors (TFs) and their chromosomal targets. Howe... Read more »

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ATAC-seq

Differential DNA methylation in iPSC-derived dopaminergic neurons: ...
Published: April, 2024

Abstract: Introduction A microdeletion including the SNORD116 gene (SNORD116 MD) has been shown to drive the Prader-Willi syndrome (PWS) feat... Read more »

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Premium RRBS Kit

Epigenetics and suicide: investigating altered H3K14ac unveiled dif...
Published: March, 2024

Abstract: Background: Environmental factors make an important contribution to suicide. Histone tails are prone to different modifications, leading to ch... Read more »

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ChIPmentation

TET2 Deficiency Increases the Competitive Advantage of Hematopoieti...
Published: March, 2024

Abstract: Ten-Eleven Translocation-2 (TET2) mutations drive the expansion of mutant hematopoietic stem cells (HSCs) in clonal hematopoiesis (CH). However, th... Read more »

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Chromatin Shearing

Integrative network analysis of differentially methylated regions t...
Published: March, 2024

Abstract: Integrative network analysis (INA) is important for identifying gene modules or epigenetically regulated molecular pathways in diseases. This study... Read more »

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Infinium Human MethylationEPIC Array Service

High-throughput sequencing of insect specimens with sub-optimal DNA...
Published: March, 2024

Abstract: Entomological sampling and storage conditions often prioritise efficiency, practicality and conservation of morphological characteristics, and may ... Read more »

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Tagmentase

Technical considerations for cost-effective transposon directed ins...
Published: March, 2024

Abstract: Transposon directed insertion-site sequencing (TraDIS), a variant of transposon insertion sequencing commonly known as Tn-Seq, is a high-throughput... Read more »

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Tagmentase

Protocol to isolate nuclei from Chlamydomonas reinhardtii for ATAC ...
Published: March, 2024

Abstract: Highlights Optimized isolation of nuclei from the green model alga Chlamydomonas reinhardtii Tag-free isolation from both cell-w... Read more »

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ATAC-seq

Chromatin profiling reveals TFAP4 as a critical transcriptional reg...
Published: March, 2024

Abstract: Background Satellite cells are myogenic precursor cells in adult skeletal muscle and play a crucial role in skeletal muscle regeneration, maintena... Read more »

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Antibody iDeal ChIP-seq Kit for Histones

On the identification of differentially-active transcription factor...
Published: March, 2024

Abstract: ATAC-seq has emerged as a rich epigenome profiling technique, and is commonly used to identify Transcription Factors (TFs) underlying given phenome... Read more »

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Tagmentase

SURVIVIN IN SYNERGY WITH BAF/SWI COMPLEX BINDS BIVALENT CHROMATIN R...
Published: March, 2024

Abstract: This study explores a regulatory role of oncoprotein survivin on the bivalent regions of chromatin (BvCR) characterized by concomitant deposition o... Read more »

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Antibody

Focal cortical dysplasia type II-dependent maladaptive myelination ...
Published: March, 2024

Abstract: Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of intractable epilepsy. FCDs are classified in... Read more »

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IPure kit iDeal ChIP-seq Kit for Transcription Factors

Pervasive translation of Xrn1-sensitive unstable long non-coding RN...
Published: March, 2024

Abstract: Despite being predicted to lack coding potential, cytoplasmic long non-coding (lnc)RNAs can associate with ribosomes. However, the landscape and bi... Read more »

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D-Plex small RNA-seq

A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at ...
Published: March, 2024

Abstract: Purpose: DNA methylation alterations are widespread in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), some of which appear to hav... Read more »

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MagMeDIP kit

Making Biological Ageing Clocks Personal
Published: February, 2024

Abstract: Background Age is the most important risk factor for the majority of human diseases. Addressing the impact of age-related diseases has becom... Read more »

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Infinium Human MethylationEPIC Array Service

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